Alexis B. Lyons

ORCID: 0000-0003-0799-5680
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About
Contact & Profiles
Research Areas
  • Hidradenitis Suppurativa and Treatments
  • Skin Protection and Aging
  • Colorectal and Anal Carcinomas
  • melanin and skin pigmentation
  • Dermatologic Treatments and Research
  • Acne and Rosacea Treatments and Effects
  • Infection Control and Ventilation
  • COVID-19 and healthcare impacts
  • Chemotherapy-related skin toxicity
  • Nonmelanoma Skin Cancer Studies
  • Microscopic Colitis
  • Anorectal Disease Treatments and Outcomes
  • Cutaneous Melanoma Detection and Management
  • Photodynamic Therapy Research Studies
  • Facial Rejuvenation and Surgery Techniques
  • Infection Control in Healthcare
  • Atherosclerosis and Cardiovascular Diseases
  • Laser Applications in Dentistry and Medicine
  • Reconstructive Facial Surgery Techniques
  • Cancer Immunotherapy and Biomarkers
  • Dermatology and Skin Diseases
  • Inflammasome and immune disorders
  • Oral Health Pathology and Treatment
  • Genetic and rare skin diseases.
  • Healthcare Systems and Technology

Forefront of Dermatology
2025

Henry Ford Health System
2019-2024

University of California, Irvine
2024

Henry Ford Hospital
2018-2022

Moy, Fincher, Chipps Medical Group
2018-2019

UCLA Medical Center
2019

Harbor–UCLA Medical Center
2019

Hidradenitis Suppurativa Foundation
2019

Michigan United
2019

Eastern Virginia Medical School
2015-2017

<h3>Importance</h3> Hidradenitis suppurativa (HS) disproportionately affects women of childbearing potential. There is a paucity data regarding the HS disease course during pregnancy and in postpartum period. <h3>Objective</h3> To explore <h3>Design, Setting, Participants</h3> A retrospective cohort study was conducted on patients Henry Ford Health System, Detroit, Michigan—a large, academic, urban referral center. Women with diagnosis who became pregnant between January 1, 2008, December...

10.1001/jamadermatol.2020.0777 article EN JAMA Dermatology 2020-04-29

<ns4:p>Hidradenitis suppurativa (HS) is a chronic, inflammatory, recurrent, and debilitating skin disease of the hair follicle unit that typically develops after puberty. HS has significant negative impact on both quality life (QOL) patients affected by this as well family members caregivers. However, pathogenesis multifactorial still remains to be fully elucidated, which makes development treatments difficult. The last 10 years have seen surge in research, many new findings come light, yet...

10.12688/f1000research.26083.1 preprint EN cc-by F1000Research 2020-08-26

Human skin is exposed to visible light (VL; 400-700 nm) and long-wavelength ultraviolet A1 (UVA1) radiation (370-400 after the application of organic broad-spectrum sunscreens. The biologic effects these wavelengths have been demonstrated; however, a dose-response has not investigated. Ten subjects with Fitzpatrick phototype IV-VI were enrolled. Subjects irradiated 2 sources (80-480 J cm-2 ): one comprising VL less than 0.5% UVA1 (VL+UVA1) other pure VL. Skin responses evaluated for weeks...

10.1111/php.13157 article EN Photochemistry and Photobiology 2019-08-29

The role of topical antioxidants (AOs) on visible light plus ultraviolet A1 (VL+UVA1)-induced skin changes were evaluated. Twenty subjects with phototypes (SPTs) I-VI had placebo and concentrations an AO blend applied to their back (AO 0.5%, 1.0% 2.0%). Treated control sites irradiated VL+UVA1. Colorimetric diffuse reflectance spectroscopy (DRS) assessments performed immediately, 24 h 7 days after irradiation. Subjects SPT I-III erythema that faded within h, while IV-VI persistent...

10.1111/php.13525 article EN Photochemistry and Photobiology 2021-09-22

Large surgical defects after Mohs micrographic surgeries (MMS) often require rotation or advancement flaps, skin grafts, delayed reconstruction use of tissue expanders. For patients with limited redundancy, wounds may also heal by secondary intention. Elderly undergoing MMS full-thickness exposing bone pose a unique set healing barriers, such as immunosuppression, increased infection risk, poor tolerance to chiseling for pinpoint bleeding, and difficulty in reaching apply dressings successfully.

10.1016/j.jdcr.2018.03.015 article EN cc-by-nc-nd JAAD Case Reports 2018-08-01
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