A5100606638- Remote Sensing and LiDAR Applications
- PARP inhibition in cancer therapy
- 3D Surveying and Cultural Heritage
- Ovarian cancer diagnosis and treatment
- Satellite Image Processing and Photogrammetry
- Remote Sensing in Agriculture
- Cancer Immunotherapy and Biomarkers
- Climate variability and models
- Species Distribution and Climate Change
- Optical measurement and interference techniques
- Electrocatalysts for Energy Conversion
- Esophageal Cancer Research and Treatment
- Plant Ecology and Soil Science
- Colorectal Cancer Treatments and Studies
- Immune Cell Function and Interaction
- Advanced Breast Cancer Therapies
- Video Surveillance and Tracking Methods
- Immunotherapy and Immune Responses
- Proteins in Food Systems
- Hydrology and Drought Analysis
- 3D Shape Modeling and Analysis
- Coastal wetland ecosystem dynamics
- Environmental Changes in China
- Advanced Optical Sensing Technologies
- Forest ecology and management
Zhejiang University
2024
Huazhong University of Science and Technology
2024
Tongji Hospital
2024
Xi'an Railway Survey and Design Institute
2016-2024
Sir Run Run Shaw Hospital
2024
Zhongshan Hospital
2023
Oregon Health & Science University
2021-2023
Fudan University
2023
Sichuan University of Science and Engineering
2022
Nanjing University of Finance and Economics
2022
Abstract T cells are fundamental components in tumour immunity and cancer immunotherapies, which have made immense strides revolutionized treatment paradigm. However, recent studies delineate the predicament of cell dysregulation microenvironment compromised efficacy immunotherapies. CRISPR screens enable unbiased interrogation gene function revealed functional determinators, genetic regulatory networks, intercellular interactions life cycle, thereby providing opportunities to revamp In this...
(2021). An active-passive fusion strategy and accuracy evaluation for shallow water bathymetry based on ICESat-2 ATLAS laser point cloud satellite remote sensing imagery. International Journal of Remote Sensing: Vol. 42, No. 8, pp. 2783-2806.
Two-media photogrammetry appears to be a useful technology for mapping shallow water depth. The objective of this paper is explore the feasibility bathymetry using satellite two-media photogrammetry. This presents technique WorldView-2 stereo multispectral imagery. In method, near-infrared band used sun glint elimination. A combination Scale Invariant Feature Transform and Semi-Global Matching algorithm adopted dense matching. Rational Function Model applied raw Digital Elevation generation...
Neoadjuvant chemotherapy (nCT) has been the recommended treatment for locally advanced esophageal squamous cell carcinoma (ESCC). The addition of programmed death protein 1 (PD-1) inhibitor to nCT may improve oncologic outcome and survival. However, high-level evidence neoadjuvant immunotherapy (nIT) combined with in resectable ESCC patients are still lacking. Hence, we describe this randomized controlled trial order assess efficacy safety nivolumab combination (stage II-III) patients.This...
Multispectral Lidar System can emit simultaneous laser pulses at the different wavelengths. The reflected multispectral energy is captured through a receiver of sensor, and return signal together with position orientation information sensor recorded. These recorded data are solved GNSS/IMU for further post-processing, forming high density 3D point clouds. As first commercial airborne Optech Titan system capable collecting clouds from all three channels 532nm visible (Green), 1064 nm near...
The new-generation photon-counting laser altimeter aboard the Ice, Cloud, and Land Elevation Satellite-2 (ICESat-2) has acquired unprecedented high-density data on global surface. continuous analysis calibration of potential systematic biases in are important for generating highly accurate products. Current studies mainly calibrate absolute bias altimeters based external reference data. There few that focus relative long-term This paper explores a method ICESat-2 track crossovers first time....
Abstract Changes in precipitation storm characteristics especially extreme events have been frequently reported during recent years, which poses great challenges for flood controls of reservoir basins. In this study, we present a comprehensive examination on the evolution properties two distinct rainy seasons Changtan Reservoir Basin located southeastern coast China. We compare differences duration, inter-storm period, average intensity, and with-in pattern between Meiyu season (MFS) typhoon...
With the rapid developments of sensor technology, high spatial resolution imagery and airborne Lidar point clouds can be captured nowadays, which make classification, extraction, evaluation analysis a broad range object features available. High imagery, dataset parcel map widely used for classification as information carriers. Therefore, refinement objects is made possible urban land cover. The paper presents an approach to based image (OBIA) combing clouds. advanced workflow cover designed...
Automatic large-scale building extraction from the LiDAR point clouds and remote sensing images is a growing focus in fields of sensor applications sensing. However, this task remains highly challenging due to complexity sizes, shapes, surrounding environments. In addition, discreteness, sparsity, irregular distribution clouds, lighting, shadows, as well occlusions images, also seriously affect accuracy extraction. To address above issues, we propose new unsupervised algorithm PBEA (Point...
The Ice, Cloud and Land Elevation Satellite (ICESat-2) offers an unprecedented high density of laser data on the Earth’s surface. Evaluation calibration geolocation errors are important for scientific application data. In this study, a crossover method is proposed to evaluate calibrate errors. This mainly relies small-scale reference consistency conditions at trajectory crossovers. By matching profile measurements ascending descending altimeter tracks find location where discrepancy...
Abstract Background Combining poly (ADP-ribose) polymerase (PARP) with phosphatidylinositol-3-kinase (PI3K) pathway inhibitors is supported by strong preclinical rationale. We sought to assess safety and determine a recommended phase 2 dose (RP2D) for PARP inhibitor olaparib combined the AKT inhibitor, capivasertib, evaluate molecular markers of response resistance. Methods As part larger 1b trial, we performed lead in capivasertib followed expansion (n=24) endometrial, triple negative...
<p>Supplementary Figure S4</p>
<p>Supplementary Figure S2</p>
<p>Supplementary Figure S1</p>
<p>Supplementary Figures Legends</p>
<div>AbstractPurpose:<p>On the basis of strong preclinical rationale, we sought to confirm recommended phase II dose (RP2D) for olaparib, a PARP inhibitor, combined with AKT inhibitor capivasertib and assess molecular markers response resistance.</p>Patients Methods:<p>We performed safety lead-in followed by expansion in endometrial, triple-negative breast, ovarian, fallopian tube, or peritoneal cancer. Olaparib 300 mg orally twice daily on 4-day 3-day off schedule...
The photon-counting Advanced Terrain Laser Altimeter System (ATLAS) onboard the Ice, Cloud, and Land Elevation Satellite (ICESat-2) provides high-density laser point data on Earth's surface. Previous calibration methods for geolocation errors required fields or large-scale reference data. In this study, a error method based crossovers is proposed, which mainly relies consistency conditions at trajectory crossovers. results show that proposed can be used to estimate of data, total 3.57m,...
<div>AbstractPurpose:<p>On the basis of strong preclinical rationale, we sought to confirm recommended phase II dose (RP2D) for olaparib, a PARP inhibitor, combined with AKT inhibitor capivasertib and assess molecular markers response resistance.</p>Patients Methods:<p>We performed safety lead-in followed by expansion in endometrial, triple-negative breast, ovarian, fallopian tube, or peritoneal cancer. Olaparib 300 mg orally twice daily on 4-day 3-day off schedule...