A5101954535- Aerogels and thermal insulation
- Nanoparticle-Based Drug Delivery
- Nanoplatforms for cancer theranostics
- Ultrasonics and Acoustic Wave Propagation
- MXene and MAX Phase Materials
- Advanced biosensing and bioanalysis techniques
- RNA Interference and Gene Delivery
- Advanced Memory and Neural Computing
- Dental materials and restorations
- Dendrimers and Hyperbranched Polymers
- Dental Implant Techniques and Outcomes
- Supramolecular Self-Assembly in Materials
- Graphene and Nanomaterials Applications
- Quasicrystal Structures and Properties
- Educational and Technological Research
- Laser Applications in Dentistry and Medicine
- Synthetic Organic Chemistry Methods
- Hydrogels: synthesis, properties, applications
- Hydrogen Storage and Materials
- Flow Measurement and Analysis
- Nanocluster Synthesis and Applications
- Electron and X-Ray Spectroscopy Techniques
- Biochemical Acid Research Studies
- Polymer composites and self-healing
- High-Velocity Impact and Material Behavior
Beijing Normal University
2025
Shenyang Pharmaceutical University
2022-2024
Beijing Institute of Technology
2023-2024
University of Manchester
2019-2024
Henry Royce Institute
2022-2024
Xuzhou Medical College
2024
University of Electronic Science and Technology of China
2022-2023
National Engineering Research Center of Electromagnetic Radiation Control Materials
2023
Emory and Henry College
2023
Wuhan University
2015-2017
Abstract Additive manufacturing (AM) technologies appear as a paradigm for scalable manufacture of electrochemical energy storage (EES) devices, where complex 3D architectures are typically required but hard to achieve using conventional techniques. The combination these and innovative material formulations that maximize surface area accessibility ion transport within electrodes while minimizing space growing interest. Herein, aqueous inks composed atomically thin (1–3 nm) 2D Ti 3 C 2 T x...
Phenylboronic acid (PBA) is a tumor-targeting molecule, but its nonspecific interaction with normal cells or other components containing cis-diol residues undoubtedly limits potential application in drug delivery. Herein, we developed fructose-coated mixed micelles via PBA-terminated polyethylene glycol monostearate (PBA-PEG-C18) and Pluronic P123 (PEG20-PPG70-PEG20) to solve this problem, as the stability of borate formed by PBA fructose was dramatically dependent on pH. The fluorescence...
When incubating the pH and redox dual-sensitive CCL/SS micelles with MCF-7/ADR cells, they could sufficiently overcome drug resistance to deliver DOX into leading apoptosis of tumor cells.
A reduction-sensitive polymeric prodrug PEG-<italic>b</italic>-PMPMC-<italic>g</italic>-PTX was designed. The self-assemblies of could deliver drugs with different action mechanisms into tumor cells, leading to the apoptosis cells effectively.
CYP199A4 is a cytochrome P450 and can catalyze the hydroxylation of 4-propionylbenzoic acid (4-pIBA) to generate α-hydroxyketone with high stereoselectivity. The F182L mutant (F182L-CYP199A4) has been shown support cleavage C-C bond between carbonyl hydroxyl groups α-hydroxyketone, whereas wild-type cannot. To uncover how Phe182 regulates substrate reactivity, we conducted classical molecular dynamics (MD) quantum mechanics/molecular mechanics (QM/MM) MD simulations on these systems. results...
Aerogels are attracting increasing interest due to their functional properties, such as lightweight and high porosity, which make them promising materials for energy storage advanced composites. Compressive deformation allows the nano- microstructure of lamellar freeze-cast aerogels be tailored toward aforementioned applications, where a 3D nanostructure closely spaced, aligned sheets is desired. Quantitatively characterizing microstructural evolution during compression needed allow...
The study aimed to evaluate the impact of varying modulus elasticity (MOE) values dental implants on deformation and von Mises stress distribution in implant systems peri-implant bone tissues under dynamic cyclic loading. implant-bone interface was characterised as frictional contact, initial induced using interference fit method effectively develop a finite element model for an immediately loaded implant-supported denture. Using Ansys Workbench 2021 R2 software, analysis conducted examine...
Metal fibre reinforcements to polymer matrix composites (PMCs) bolster architectural flexibility and functionality affordably but feature a relatively weak interfacial bonding if not surface treated. This work demonstrates that Plasma Electrolytic Oxidation is promising prepare woven hybrid Al2O3/Al for PMCs. The compressive behaviour (a critical design parameter in structural design) of PMCs reinforced by ∼9 13 vol% γ-Al2O3/Al fibres with different oxide-to-metal ratios (∼20-50 vol%)...
The structures of eight related known intermetallic structure types are the impetus to this paper: Li21Si5, Mg44Rh7, Zn13(Fe,Ni)2, Mg6Pd, Na6Tl, Zn91Ir11, Li13Na29Ba19, and Al69Ta39. All belong F43m space group, have roughly 400 atoms in their cubic unit cells, built up at least partially from gamma-brass structure, exhibit pseudo-tenfold symmetric diffraction patterns. These axes lie {110} directions, thus present a paradox. set is comprised three pairs perpendicular directions. Yet no 3D...
Herein, we prepared folate-targeting core crosslinked polymeric micelles (CCL/FA) containing multiple disulfide bonds located at the interface and of to co-deliver doxorubicin (DOX) P-glycoprotein (P-gp) inhibitor tariquidar (TQR) for reversing drug resistance. The stability redox-responsive behavior CCL/FA was evaluated through changes in morphology, molecular weight hydrodynamic size. On one hand, possessed good stability, which led suppression release from CCL physiological environment....
Using the host-guest interaction between β-cyclodextrin (β-CD) and adamantane (Ad), borate formation phenylboronic acid (PBA) cis-diols, a smart pH-responsible targeting drug delivery nanovehicle, PBA-PEG-CD/Ad-lys(Diol)-PCL, was prepared via one-step self-assembly. Under physiological conditions, targeted PBA function could be restrained by binding with diol components located at interface of self-assemblies, hydrophilic PEG segments shielded simultaneously. When environmental pH decreased,...
In this paper, we first synthesized a novel disulfide-coupled bis-(cyclic carbonate) (TDCSS) monomer. After ring-opening co-polymerization (ROP) of TDCSS and trimethylene carbonate (TMC) initiated by mono-methoxyl poly(ethylene glycol), the crosslinked reduction-sensitive copolymer PEG-P(TMC-co-TDCSS) was obtained via facile one-step procedure for efficient delivery doxorubicin (DOX) into cancer cells. To serve as controls, PEG-P(TMC-co-TDCCC), which has an analogous structure without...
To achieve the goal of neuromorphic computing hardware implementation with extremely high efficiency, low power consumption, and density, it is necessary to develop transistor-free memristors implement differential operation without subtraction circuits. In this study, argon ion irradiation was used during fabrication process a single crystalline LiNbO3 (LN) thin film controllably introduce oxygen vacancies (OVs) into bottom surface, which realized modulation OVs based on excellent...
Abstract One of the key steps toward constructing neuromorphic systems is to develop reliable bio‐realistic synaptic devices. Here, memristors based on single‐crystalline LiNbO 3 (SC‐LNO) thin film are fabricated as artificial synapses. A reservoir oxygen vacancies induced by Ar + irradiation resemble vesicles containing neurotransmitters. Phenomena saturation and adaptivity, short‐term plasticity, paired‐pulse facilitation, depression, long‐term potentiation successfully mimicked. The...
Journal Article High-temperature EDS and EBSD Analysis – Enabling In Situ Heating for Direct Observation of Phase Transformations in the SEM Get access Haithem Mansour, Mansour Oxford Instruments NanoAnalysis, High Wycombe, United Kingdom Corresponding author: Haithem.mansour@oxinst.com Search other works by this author on: Academic Google Scholar Simon Burgess, Burgess Patrick Trimby, Trimby Kim Larsen, Larsen Jack Donoghue, Donoghue Henry Royce Institute, Department Materials, The...
The curing of THEIC-modified polyester and polyamideimide enamels under controlled thermal conditions was discussed. Real-time FTIR microspectroscopy were employed to determine solvent evaporation, crosslinking reactions, retained degree cure wire samples. A possible mechanism suggested based upon the findings.