A5059173291- Animal Virus Infections Studies
- Animal Disease Management and Epidemiology
- Plant Virus Research Studies
- Viral gastroenteritis research and epidemiology
- Herpesvirus Infections and Treatments
- Virus-based gene therapy research
- Influenza Virus Research Studies
- Viral Infections and Immunology Research
- Cytomegalovirus and herpesvirus research
- HIV Research and Treatment
- Vector-Borne Animal Diseases
- Viral-associated cancers and disorders
- T-cell and Retrovirus Studies
- Respiratory viral infections research
- Viral Infections and Vectors
- Toxoplasma gondii Research Studies
- Soil Management and Crop Yield
- Salmonella and Campylobacter epidemiology
- Plant and Fungal Interactions Research
- Microbial infections and disease research
Concordia University Wisconsin
2023-2024
Universidade Federal do Rio Grande do Sul
2016-2023
Secretaria de Agricultura e Abastecimento
2020-2023
Brazilian Agricultural Research Corporation
2022-2023
Instituto de Saúde
2022
Two full-genome sequences of porcine circovirus type 3 (PCV3) are reported. The genomes were recovered from pooled serum samples sows who had just delivered litters with variable numbers stillbirths. two circular (PCV3-BR/RS/6 and PCV3-BR/RS/8) 2,000 nucleotides long contain open reading frames (ORFs) oriented in opposite directions that encode the putative capsid (Cap) replicase (Rep) proteins. intergenic region contains a stem-loop motif, as reported for other circoviruses. Rolling circle...
In South America, the evolutionary history of influenza A virus (IAV) in swine has been obscured by historically low levels surveillance, and this hampered assessment zoonotic risk emerging viruses. The extensive genetic diversity IAV observed globally attributed mainly to bidirectional transmission between humans pigs. We conducted surveillance Brazil during 2011–2020 characterized 107 H1N1, H1N2, H3N2 IAVs. Phylogenetic analysis based on HA NA segments revealed that human seasonal IAVs...
Once established in the human population, 2009 H1N1 pandemic virus (H1N1pdm09) was repeatedly introduced into swine populations globally with subsequent onward transmission among pigs. To identify and characterize human-to-swine H1N1pdm09 introductions Brazil, we conducted a large-scale phylogenetic analysis of 4,141 H1pdm09 hemagglutinin (HA) 3,227 N1pdm09 neuraminidase (NA) gene sequences isolated from humans between 2022. Phylodynamic revealed that during period 2011, there rapid to...
A study was conducted to investigate the serum virome of sows with and without stillbirths after farrowing. Sera from at least one stillbirth or normal litters were collected immediately Viral DNA extracted pools submitted high throughput sequencing. No differences in proportion virus-related reads found both groups (p > 0.05). variety viral genomes identified, mostly representative three families: Anelloviridae, Circoviridae Smacoviridae. Besides, a number novel unclassified circular...
Wild birds carry a number of infectious agents, some which may have pathogenic potential for the host and others species, including humans. Domestic pigeons (Columba livia) are important targets study since these increasingly cohabit urban spaces, being possible spillover sources pathogens to In present study, two genomes (PiGyV_Tq/RS/Br PiGyV_RG/RS/Br), representative Gyrovirus genus, family Anelloviridae, were detected in sera free-living collected Southern Brazil. The exhibit less than...
(SVA) is a picornavirus that endemic in swine, causing vesicular disease clinically indistinguishable from other diseases, like foot-and-mouth disease. The widespread viral circulation, constant evolution, and economic losses caused to the swine industry emphasize need for measures control agent. In this study, we evaluated immunogenicity of whole-virus-inactivated vaccine using representative contemporary Brazilian SVA strain Balb/ByJ mice. animals were vaccinated with two doses by an...
Zoonotic infections (swine-human) caused by influenza A viruses (IAVs) have been reported and linked to close contact between these species. Here, we describe eight human IAV variant (6 mild 2 severe cases, including 1 death) detected in Paraná, Brazil, during 2020-2023. Genomes recovered were closely related Brazilian swIAVs of three major lineages (1 A.3.3.2/pdm09, 1B/human-like, H3.1990.5), H1N1v, two H1N2v, H3N2v one H1v. Five H1v pdm09 lineage, (H1N2v) grouped within 1B.2.3 clade, the...
Feline immunodeficiency virus (FIV), like other retroviruses, displays large genomic divergence when different isolates are compared. In this study, 31 FIV positive samples of domestic cats from Porto Alegre, RS, Brazil were used aiming at a detailed characterization and better understanding the molecular epidemiology in Brazil. The proviral env genes partially amplified, sequenced compared with another 237 sequences continents. We identified several Brazilian highly supported clades (A, B1,...
Since its first identification in 2016, porcine circovirus 3 (PCV3) has been detected healthy and/or diseased swine many countries worldwide. In a previous study by our group, PCV3 was sera of sows which had at least one stillborn piglet the last parturition. As such, it became important to investigate if presence sows' could be associated occurrence stillbirths. With that aim, frequency infections and viral DNA loads investigated through real-time quantitative PCR 89 serum samples just...
In the present study, complete nucleotide sequence of porcine circovirus 3 (PCV3) recovered from wild boars lymph nodes is described. The full genome was named PCV3-wb/Br/RS and comprises 2,000 nucleotides with two open reading frames (ORFs) a stem-loop motif in intergenic region. ORFs are oriented opposite directions encode putative capsid (Cap) replicase (Rep) proteins. Based on amino acid analysis, as well most sequences classified PCV3b. Phylogenetic analysis including 97 PCV3 available...
The surface envelope (SU) protein determines the cell tropism and consequently pathogenesis of feline leukemia virus (FeLV) in felids. Recombination exogenous FeLV (exFeLV) with endogenous retroviruses (enFeLV) allows emergence more pathogenic variants. Currently, phenotypic testing through interference assays is only method to distinguish among subgroups—namely, FeLV-A, -B, -C, -E, -T. This study proposes a new for classification based on molecular analysis SU gene. A total 404 publicly...
Bovine alphaherpesvirus 1 (subtypes 1.1, 1.2a, and 1.2b), type 5 5a, 5b, 5c), bubaline herpesvirus (BuHV-1) induce highly, though not fully cross-reactive serological responses. Most types subtypes of these viruses circulate particularly in countries the southern hemisphere, notably Brazil Argentina. Therefore, detection infected animals is important defining prevention control strategies, when flocks are destined for international trade. Identification herds most often achieved by assays...
Abstract Background Influenza A virus (IAV) circulates within human and swine populations, pigs are considered intermediate hosts for the generation of IAV with pandemic potential. Surveillance characterization IAVs circulating in pig populations crucial to strain match vaccines control transmission quantify potential humans. Methods Here, we characterized genetic antigenic diversity Brazilian between 2010-2018. Phylogenetic maximum-likelihood trees were generated 84 hemagglutinin (HA) gene...
Over the last decade, viral metagenomics has been established as a non-targeted approach for identifying viruses in stock animals, including pigs. This led to identification of vast diversity small circular ssDNA viruses. The present study focuses on investigation eukaryotic Rep-encoding single-stranded (CRESS) DNA genomes serum commercially reared pigs from southern Brazil. Several CRESS were detected, representatives families Smacoviridae (n=5), Genomoviridae (n=3), Redondoviridae (n=1),...
A leucose enzootica bovina e uma enfermidade cronica que acarreta prejuizos economicos ao produtor. Detectar a presenca de animais infectados etapa importante no controle desta doenca. Portanto, neste trabalho procurou-se investigar prevalencia do virus na regiao Alto Uruguai Catarinense e, paralelamente, desenvolver um ensaio imunoenzimatico (ELISA) capaz discriminar sorologicamente positivos negativos para o da (BLV). Para padronizacao ELISA foram realizadas titulacoes em bloco antigeno...