A5015541583- Nanoplatforms for cancer theranostics
- Advanced Nanomaterials in Catalysis
- Advanced biosensing and bioanalysis techniques
- Luminescence and Fluorescent Materials
- Nanoparticle-Based Drug Delivery
- Nanocluster Synthesis and Applications
- Electrochemical sensors and biosensors
- MXene and MAX Phase Materials
- Wound Healing and Treatments
- Biosensors and Analytical Detection
- Advanced Photocatalysis Techniques
- Electrospun Nanofibers in Biomedical Applications
- Hemostasis and retained surgical items
- Synthesis and properties of polymers
- Photoacoustic and Ultrasonic Imaging
- Dendrimers and Hyperbranched Polymers
- Magnetic Properties and Synthesis of Ferrites
- Photodynamic Therapy Research Studies
- Flame retardant materials and properties
- Graphene and Nanomaterials Applications
- Bone and Joint Diseases
- Cancer Research and Treatments
- Electromagnetic wave absorption materials
- Advancements in Battery Materials
- Therapeutic Uses of Natural Elements
First Affiliated Hospital of Xi'an Jiaotong University
2021-2025
Xi'an Jiaotong University
2014-2024
China XD Group (China)
2017-2021
Chemical Synthesis Lab
2017-2020
Equilibrium Research
2020
Abstract Nanozymes are considered as the promising antimicrobial agents due to enzyme‐like activity for chemo‐dynamic therapy (CDT). However, it remains a challenge develop novel nanozyme systems achieving stimuli‐responsive, and efficient catalysis with multimodal synergistic enhancement. In this work, near‐infrared (NIR) plasmonic‐enhanced photothermal performance effective applications proposed. A Ti 3 C 2 MXene/Fe‐MOFs composite (MXM) NIR CDT combined properties is successfully developed...
Multifunctional nanodrugs with the integration of precise diagnostic and effective therapeutic functions have shown great promise in improving efficacy cancer therapy.
A highly efficient dual-modal imaging platform by using bright AIE dots was constructed to achieve precise cancer diagnostics.
Metal–organic frameworks (MOFs) are significant useful molecular materials as a result of their high surface area and flexible catalytic activities by tuning the metal centers ligands. MOFs have attracted great attention efficient nanozymes recently; however, it is still difficult to understand polymetallic for enzymatic catalysis because complicated structure interactions. Herein, bimetallic NiFe2 MOF octahedra were well prepared exhibited enhanced peroxidase-like activities. The...
Metal–organic frameworks (MOFs) are widely used to mimic enzymes for catalyzing chemical reactions; however, low enzyme activity limit their large-scale application. In this work, gold nanorods/metal–organic (Au NRs/Fe-MOF) hybrids were successfully synthesized photo-enhanced peroxidase-like catalysis and surface-enhanced Raman spectroscopy (SERS). The enzyme-like of Au NRs/Fe-MOF was significantly enhanced under localized surface plasmon resonance (LSPR), because the hot electrons produced...
Aggregation-induced emission (AIE) nanoparticles have been widely applied in photodynamic therapy (PDT) over the past few years. However, amorphous nanoaggregates usually occur their preparation, resulting loose packing with disordered molecular structures. This still allows free intramolecular motions, thus leading to limited brightness and PDT efficiency. Herein, we report deep-red AIE nanocrystals (NCs) of DTPA-BS-F by following facile method nanoprecipitation. It is observed that NCs...
Multistage pH/H<sub>2</sub>O<sub>2</sub>/redox-responsive 3D nanoflowers that fully exploit the tumor microenvironment achieve highly specific guided multimode diagnosis with excellent synergistic chemotherapy and photodynamic therapy effects both<italic>in vitro</italic>and<italic>in vivo</italic>.
The COVID-19 pandemic has spread to every corner of the world and seriously affected our health daily activities in past three years; thereby, it is still urgent develop various simple, quick, accurate methods for early detection severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. Nanozymes, a kind nanomaterial with intrinsic enzyme-mimicking activity, have emerged as suitable alternative both therapy diagnosis SARS-CoV-2. Here, ultrasensitive ultrafast...
To achieve super-resolution imaging in biological research using stimulated emission depletion (STED) nanoscopy, organic luminescent materials and their corresponding fluorescent nanoparticles with high brightness photostability are of great significance. Herein, donor-acceptor-typed DBTBT-4C8 bearing flexible alkyl chains was developed, not only to afford deep-red from 600 800 nm but also obtain the absolute photoluminescence quantum yields 25%. After that, well-defined monodispersed...
Nicotinamide adenine dinucleotide (NADH) is central to metabolism and implicated in various diseases. Herein, nanohybrids of gold nanostars metal–organic frameworks are devised demonstrated as a dual-mode NADH sensor, for which colorimetric detection enabled by its peroxidase-like nanozyme property Raman realized surface-enhanced scattering with the limit low 28 pM. More importantly, this probe enables real-time SERS monitoring living cells, providing unique tool investigate dynamic cellular...
Abstract Burn wound healing continues to pose significant challenges due excessive inflammation, the risk of infection, and impaired tissue regeneration. In this regard, an antibacterial, antioxidant, anti‐inflammatory nanocomposite (called HPA) that combines a nanosystem using hexachlorocyclotriphosphazene natural polyphenol Phloretin with silver nanoparticles (AgNPs) is developed. HPA effectively disperses AgNPs mitigate any toxicity caused by aggregation while also showing pharmacological...
Liver cancer is currently among the most challenging cancers to diagnose and treat. It of prime importance minimize side effects on healthy tissues reduce drug resistance for precise diagnoses effective treatment liver cancer. Herein, we report a facile but high-yield approach fabricate multifunctional nanomaterial through loading chitosan metformin Mn-doped Fe3O4@MoS2 nanoflowers. Fe3O4 cores are used as simultaneous T1/T2 magnetic resonance imaging (MRI) agents sensitive accurate...
Multifunctional intelligent theranostics agents are promising for next-generation oncotherapy. We fabricated a tumor-microenvironment (TME)-responsive carbon nanotube (CNT)-based nanoplatform T1 weighted magnetic resonance imaging (MRI)-guided synergistic photodynamic and photothermal therapy (PDT PTT). CNTs convert near infrared (NIR) radiation into hyperthermia PTT, can effectively deliver their cargo cells due to unique 1D nanostructure. The CNT@MnO2-PEG@Ce6 nanomedicine was internalized...
SRY-related high-mobility-group box 9 (Sox9) gene is a cartilage-specific transcription factor that plays essential roles in chondrocyte differentiation and cartilage formation. The aim of this study was to investigate the feasibility genetic delivery Sox9 enhance chondrogenic human umbilical cord blood-derived mesenchymal stem cells (hUC-MSCs). After they were isolated from blood within 24 h after neonates, hUC-MSCs untreated or transfected with Sox9-expressing plasmid an empty vector....
Highly tunable Fe<sub>3</sub>O<sub>4</sub> nanocrystals and nanoclusters with water-dispersible superparamagnetic properties were successfully synthesized by a facile effective microwave-assisted solvothermal method.