Saarang Deshpande

ORCID: 0000-0002-9824-9052
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About
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Research Areas
  • Advanced Radiotherapy Techniques
  • Lung Cancer Diagnosis and Treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Music Therapy and Health
  • CAR-T cell therapy research
  • Lymphoma Diagnosis and Treatment
  • Medical Imaging Techniques and Applications
  • Colorectal Cancer Screening and Detection
  • Neuroscience and Music Perception
  • Multiple Myeloma Research and Treatments
  • Viral-associated cancers and disorders
  • Innovations in Medical Education
  • Chronic Lymphocytic Leukemia Research
  • Lung Cancer Treatments and Mutations
  • Phonocardiography and Auscultation Techniques
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Prostate Cancer Diagnosis and Treatment
  • MRI in cancer diagnosis
  • Grit, Self-Efficacy, and Motivation
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Multiple and Secondary Primary Cancers
  • Virus-based gene therapy research
  • Advanced Causal Inference Techniques
  • Blood disorders and treatments

University of Pennsylvania
2022-2025

Hospital of the University of Pennsylvania
2023-2024

Case Western Reserve University
2019-2023

University of Pennsylvania Health System
2023

University Hospitals Seidman Cancer Center
2022-2023

University School
2019-2022

University Hospitals of Cleveland
2019-2020

P. D. Hinduja Hospital and Medical Research Centre
2019

National Hospital
2019

Indian Institute of Information Technology Vadodara
2017

Anti-PD-1 based therapies and brentuximab vedotin (BV) have significantly improved survival in patients with classic Hodgkin lymphoma (cHL) been incorporated into earlier lines of therapy. However, there is insufficient data regarding the clinical outcomes who develop refractory disease or become intolerant BV anti-PD-1 (double refractory/intolerant; DR/INT). Here, we evaluated DR/INT cHL from 15 US academic medical centers. A total 173 were identified as DR/INT. The median overall time...

10.1038/s41408-025-01257-1 article EN cc-by-nc-nd Blood Cancer Journal 2025-03-26

The proportion of gastroesophageal junction adenocarcinoma is increasing. This study evaluated trends in early-onset gastric and esophageal cancers compared socioeconomic clinical characteristics between versus late-onset disease.We included all patients with cancer from 2004 to 2015 the National Cancer Database. Patients were categorized by age < 50, 50-69, ≥ 70 years. Differences pathologic factors assessed using chi-square test. effects demographic on overall survival (OS) Cox models.The...

10.1200/op.21.00692 article EN JCO Oncology Practice 2022-05-01

Aims: The flipped classroom (FC) model utilizes pre-class foundational learning with in-class higher-order application exercises. FC approaches have reported positive perceptions and mixed academic performance outcomes in medical education; however, little evidence exists on their impact the 56-week didactic curriculum of Physician Assistant (PA) education.Methods: A 4-week was piloted a PA behavioral medicine course (n = 34). Before class, students completed online video modules. During...

10.1080/0142159x.2019.1679360 article EN Medical Teacher 2019-10-21

Colorectal cancer (CRC) is a common cause of death and disproportionately affects non-Hispanic Black patients. Routine screening with the fecal immunochemical test (FIT) decreases CRC incidence mortality, previous literature suggests pairing FIT live outreach. Screening delays due to COVID-19 pandemic will likely increase especially in underserved communities. We implemented quality improvement (QI) project at an urban community health center (CHC) which was paired telephone The intervention...

10.1353/hpu.2022.0075 article EN Journal of Health Care for the Poor and Underserved 2022-05-01

von Willebrand disease (VWD), the most common inherited bleeding disorder, results when patients either do not make enough factor (VWF) or defective VWF. The pathophysiology of this disorder is complex but needs to be understood interpret diagnostic tests. Most have mild moderate symptoms and can adequately counseled managed by a general internist, some need consult hematologist. We review VWD, its subtypes, presentations each subtype, testing, management as well severe clinical manifestations VWD.

10.3949/ccjm.91a.22033 article EN Cleveland Clinic Journal of Medicine 2024-02-01

Objective: The aim of this study was to evaluate music therapy (MT), in conjunction with standard care, as a complementary option for asthma management pediatric patients.Methods: 173 children were randomly assigned one three groups: 1) Music: single individualized MT session along recorder and journal instructions home use; 2) Music Plus: weekly group sessions or 3) Control: care. Primary endpoints included pulmonary function tests (FEV1, FVC, FEF25-75, PEF), hospitalizations, ER visits,...

10.1080/02770903.2020.1712725 article EN Journal of Asthma 2020-01-07

A randomized control trial investigated perceived waiting time in patient and caregivers, live music’s effects on anxiety levels prior to daily radiation therapy (RT). Environmental Music Therapy (EMT) is a music intervention by therapists meant modify perception of potentially stressful environments through constructing dynamic soundscapes provide enhanced comfort safety. This study (a) rated participants’ state distress experienced the area pre-RT, (b) determined if EMT protocol moderated...

10.47513/mmd.v15i1.911 article EN Music and Medicine 2023-01-30

Background: Stereotactic body radiotherapy (SBRT) is considered the standard of care for medically inoperable early-stage non-small cell lung cancer (NSCLC). There mixed evidence on prognostic significance tumor metabolic activity assessed by FDG-PET/CT. The objectives this study were to evaluate maximum standardized uptake value (SUVmax) pretreatment and at 3 6 months after SBRT prediction control survival outcomes.Methods: Consecutive patients from a single institution with T1-2N0M0 NSCLC...

10.1016/j.adro.2023.101313 article EN cc-by-nc-nd Advances in Radiation Oncology 2023-07-09

Background: ABVD alone or in combination with radiotherapy(CMT) is the mainstay of therapy for Hodgkin lymphoma (HL). We retrospectively evaluated outcome HL patients followed up at Haemato Oncology Care Centre, Vadodara, India, between 2007 to 2016. Methods: Sixty-three were analysed this study, males 65% (n = 41), females 35% 22). The median age was 28 years (range, 8 y 75 y). Classical 93% 59) and nodular lymphocyte predominant (NLPHL) 7% 04). Stage I 1.6% 1), II 25.4%(n 16), III 58.6%(n...

10.1002/hon.2439_56 article EN Hematological Oncology 2017-06-01

Results: Whereas for machines younger than 10 years agreement between measured and stated dose was 90% overall, those over 30 old dropped to 70%.However, this picture varied with region.Linac dosimetry always better 60 Co multi-machine centres generally performed single machine institutions.We interpret latter observation as a reflection of more substantial physics infrastructure in larger centres.The data suggest virtually no dependence on the time elapsed since last system calibration at...

10.1016/s0167-8140(15)40382-2 article EN cc-by-nc-nd Radiotherapy and Oncology 2015-04-01

Introduction: TP53 alterations are associated with poor prognosis in mantle cell lymphoma (MCL). In trials of intensive chemotherapy and autologous hematopoietic transplant (auto-HCT), patients (pts) mutations had an overall survival (OS) 1.8 years (yrs) compared to 12.7 yrs for unmutated. Optimal treatment achieve durable remission is unknown. We report cellular therapy outcomes a large cohort pts altered MCL. Methods: conducted multi-site retrospective study MCL harboring mutation,...

10.1002/hon.3163_103 article EN Hematological Oncology 2023-06-01
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