Denise F. Chen

ORCID: 0000-0002-9827-3351
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About
Contact & Profiles
Research Areas
  • Epilepsy research and treatment
  • Liver Disease and Transplantation
  • Liver Disease Diagnosis and Treatment
  • EEG and Brain-Computer Interfaces
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Organ Transplantation Techniques and Outcomes
  • Bartonella species infections research
  • Venomous Animal Envenomation and Studies
  • Neonatal and fetal brain pathology
  • Pharmacological Effects and Toxicity Studies
  • Parkinson's Disease Mechanisms and Treatments
  • Multiple Sclerosis Research Studies
  • Herpesvirus Infections and Treatments
  • Intensive Care Unit Cognitive Disorders
  • Peripheral Neuropathies and Disorders
  • Systemic Lupus Erythematosus Research
  • Balance, Gait, and Falls Prevention
  • Intraoperative Neuromonitoring and Anesthetic Effects
  • Renal function and acid-base balance
  • Botulinum Toxin and Related Neurological Disorders

Emory University
2020-2025

University of Washington
2024-2025

Grady Memorial Hospital
2021

Abstract Background Seizure detection is challenging outside the clinical environment due to lack of comfortable, reliable, and practical long-term neurophysiological monitoring devices. We developed a novel, discreet, unobstructive in-ear sensing system that enables electroencephalography (EEG) recording. This first study we are aware systematically compares seizure utility EEG with simultaneously recorded intracranial EEG. In addition, present similar comparison between scalp Methods this...

10.1186/s42234-023-00135-0 article EN cc-by Bioelectronic Medicine 2024-02-07

<title>Abstract</title> Background and Objectives: Neurologic complications contribute significantly to morbidity mortality in acute liver failure (ALF). However, clinical assessment of neurologic function this population is often challenging. Continuous electroencephalography (cEEG) a low-risk, noninvasive diagnostic tool which can monitor real-time cerebral function. We aimed investigate cEEG findings prognostic significance specific EEG features cohort strictly defined ALF patients....

10.21203/rs.3.rs-4608462/v2 preprint EN cc-by Research Square (Research Square) 2025-02-06

Parkinson's disease (PD) is associated with gait and visuomotor abnormalities, but it not clear where PD patients look during ambulation. We sought to characterize the visual areas of interest explored by patients, without freezing (FOG), compared healthy volunteers (HVs). Using an eye-tracking device, we fixation patterns in 17 HVs 18 FOG, ambulatory a nonambulatory, computer-based task. During ambulation, FOG fixated more on proximal ground less target destination. displayed pattern...

10.1002/mds.28917 article EN Movement Disorders 2022-01-08

<title>Abstract</title> <bold>Background and Objectives:</bold> Neurologic complications contribute significantly to morbidity mortality in acute liver failure (ALF) present a major obstacle transplant-free survival transplantation. Preservation of cerebral function is key achieving good outcomes this population, but neurologic assessment these patients challenging. Continuous electroencephalography (cEEG) low-risk, noninvasive diagnostic tool which monitors real-time function. We aimed...

10.21203/rs.3.rs-4608462/v1 preprint EN Research Square (Research Square) 2024-07-18

Abstract BACKGROUND AND IMPORTANCE Intraoperative neurophysiological monitoring of the motor pathways during epilepsy surgery is essential to safely achieve maximal resection epileptogenic zone. Motor evoked potential (MEP) recording usually performed intermittently using a handheld stimulator or continuously through an electrode array placed on cortex. We present novel variation continuous MEP acquisition previously implanted depth electrodes in perirolandic CLINICAL PRESENTATION A...

10.1093/ons/opaa463 article EN Operative Neurosurgery 2021-01-20
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