A5026519336- Thyroid Cancer Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Science and Science Education
- Biomarkers in Disease Mechanisms
- Hedgehog Signaling Pathway Studies
- Lung Cancer Research Studies
- Bioinformatics and Genomic Networks
- Academic Research in Diverse Fields
- BRCA gene mutations in cancer
Instituto do Câncer do Estado de São Paulo
2019-2024
Universidade de São Paulo
2019-2021
Genetic analysis of sporadic medullary thyroid carcinoma (MTC) has revealed somatic variants in
Abstract Thyroid cancer is one of the most common types worldwide. It a spectrum different diseases, ranging from very indolent to lethal tumors. Differentiated Carcinoma (DTC), thyroid malignancy, has often an excellent prognosis, but some patients develop metastatic Radioiodine-Refractory disease (RAIR) that cannot be controlled locally. In this setting, and for with Medullary (MTC) Anaplastic (ATC), systemic treatment non-selective Multikinase Inhibitors (MKIs) employed improve survival...