Abstract In cancer patients, psychological distress, which encompasses anxiety, depression, and somatization, arises from the complex interplay of emotional behavioral reactions to diagnosis treatment, significantly influencing their functionality quality life. The aim was investigate factors associated with distress in patients. This prospective multicenter study, conducted by Spanish Society Medical Oncology (SEOM), included two cohorts patients (localized resected or advanced...

A cancer diagnosis can have a substantial impact on patient’s mental health and quality of life. The aim this study was to investigate the prevalence fatigue, emotional distress, uncertainty examine predictive value they life advanced patients. prospective, multicenter conducted between February 2020 May 2021 individuals diagnosed with an advanced, unresectable neoplasm prior initiating systemic antineoplastic treatment. Participants completed questionnaires quantify disease uncertainty,...

Abstract Small-cell lung cancer (SCLC) is a highly aggressive malignancy comprising approximately 15% of cancers. Only one-third patients are diagnosed at limited-stage (LS). Surgical resection can be curative in early stages, followed by platinum–etoposide adjuvant therapy, although only minority with SCLC qualify for surgery. Concurrent chemo-radiotherapy the standard care LS-SCLC that not surgically resectable, prophylactic cranial irradiation (PCI) without progression. For...

Abstract Introduction Anti-neoplastic therapy improves the prognosis for advanced cancer, albeit it is not curative. An ethical dilemma that often arises during patients’ first appointment with oncologist to give them only prognostic information they can tolerate, even at cost of compromising preference-based decision-making, versus giving full force prompt awareness, risk causing psychological harm. Methods We recruited 550 participants cancer. After appointment, patients and clinicians...

Depressive symptoms are common in individuals with advanced cancer.This study sought to analyze the relationship between physical and functional status depressive symptoms, assess role of mental adjustment across these variables people cancer.A prospective, cross-sectional design was adopted. Data were collected from 748 participants cancer at 15 tertiary hospitals Spain. Participants completed self-report measures: Brief Symptom Inventory (BSI), Mini-Mental Adjustment Cancer (Mini-MAC)...

Loss of dignity is one the main reasons for wishing an early death in patients with incurable diseases such as cancer and strongly associated psychological distress loss quality life. The present study aims to analyze perceived advanced undergoing systemic treatment their relationship sociodemographic, clinical, factors.A prospective, cross-sectional, multicenter was conducted 15 oncology departments Spain. Patients locally advanced, unresectable, or metastatic who were candidates included....

As cancer progresses, patients may experience physical decline, which can impair their ability to carry out essential daily tasks. The aim of this study was analyze the levels activity in with advanced undergoing systemic treatment and its relationship sociodemographic, clinical, psychological factors. A prospective, cross-sectional, multicenter carried 15 oncology departments Spain. Patients locally advanced, unresectable, or metastatic who were candidates for included. Participants...

Lung cancer (LC) continues to be the leading cause of cancer-related deaths in both men and women worldwide. After complete tumour resection, around half patients suffer from disease relapse, emphasising critical need for robust relapse predictors this disease. In search such biomarkers, 83 with non-microcytic lung 67 healthy volunteers were studied. Pre-operative levels sSIGLEC5 along other soluble immune-checkpoints measured correlated their clinical outcome. Soluble SIGLEC5 (sSIGLEC5)...

Abstract Purpose Patients with advanced cancer suffer significant decline of their psychological state. A rapid and reliable evaluation this state is essential to detect treat it improve quality life. The aim was probe the usefulness emotional function (EF) subscale European Organization for Research Treatment Cancer Quality Life Questionnaire C30 (EF-EORTC-QLQ-C30) assess distress in patients. Methods This a multicenter, prospective, observational study involving 15 Spanish hospitals....

Financial difficulties experienced by cancer patients negatively impact the mental health of patients. The objective this study was to examine mediating role financial between physical symptoms and depression in with advanced cancer. A prospective, cross-sectional design adopted study. data were collected from 861 participants 15 different tertiary hospitals Spain. participants’ socio-demographic characteristics using a standardized self-report form. Hierarchical linear regression models...

Objectives Communication regarding prognosis to patients with advanced cancer is fundamental for informed medical decision making. Our objective was analyse (1) the proportion of subjects who prefer know their prognosis, (2) characteristics associated patients’ preference prognostic information, (3) psychological factors that impact and 4) concordance between information perceived among physicians patients. Methods A prospective, cross-sectional design adopted. Data were collected from 748...

Uncertainty in the context of advanced cancer diagnosis often incurs significant psychological distress. The aims were to evaluate incidence distress upon and analyze whether relationship between illness uncertainty can be mediated by coping strategies.A multicenter, prospective, cross-sectional study was conducted 15 medical oncology departments across Spain. Individuals with unresectable completed questionnaires on (Michel Illness Scale, strategies (Mental Adjustment Cancer, M-MAC), (Brief...

Resilience is the capacity to adaptively confront stress. The aim of this study was evaluate psychometric properties, convergent validity, and factorial invariance Spanish version Brief Resilient Coping Scale (BRCS).

Objectives Intolerance of uncertainty (IU) has been linked to greater psychological distress, whereas hope appears act as a protective factor against in patients with cancer. The aim this study is analyse the modifying effect presence anxiety and depression advanced lung Methods Multicentre, prospective, observational, cross-sectional 145 individuals Participants completed following questionnaires: IU Scale, Hert Hope Index, Brief Symptom Inventory. Results Among cancer, were prevalent, 30%...

The purpose of the study was to compare curability expectations between clinicians and patients examine influence sociodemographic clinical variables on these satisfaction within clinician-patient relationship. This prospective study, conducted from February 2020 May 2023, involved 986 advanced cancer patients. completed questionnaires assessing treatment efficacy toxicity predictions Scale Assess Therapeutic Relationship (STAR). Seventy-four percent had an inaccurate perception curability....

Most cancers occur in older individuals, who are more vulnerable due to functional impairment, multiple comorbidities, cognitive and lack of socio-familial support. These can undermine patients' sense dignity. This study seeks compare dignity scores patients with advanced cancer on sociodemographic clinical variables analyze the predictive value anxiety, depression, limitations, social support scores.A prospective, multicenter, observational conducted participation 15 hospitals Spain from...

Patients with advanced gastrointestinal cancer must cope the negative effects of and complications.To evaluate psychological distress, quality life, coping strategies in patients colorectal compared to non-colorectal based on sex.A prospective, transversal, multicenter study was conducted 203 patients; 101 (50%) had a 102 digestive, cancer. Participants completed questionnaires evaluating distress (Brief Symptom Inventory-18), life (EORTC QLQ-C30), (Mini-Mental Adjustment Cancer) before...

Introduction This study seeks to compare expectations regarding systemic cancer treatment for advanced lung from the perspectives of both patient and medical oncologist. Methods A cross-sectional involving 17 oncologists 13 Spanish hospitals between 2021 2022. Patients with advanced, unresectable were recruited prior initiating treatment. Both patients completed NEOetic-EIT STAR. Results Seventeen specializing in participated, a mean age 36.2 years (range 28–56); 65% female. The included 298...

Background: Patients with lung cancer experience higher rates of hospitalization due to their elevated mortality and associated comorbidities. Hospital admissions among oncology patients often indicate organ vulnerability are linked poor prognosis. This study aimed assess the characteristics potential prognostic factors hospitalized patients. Methods: We retrospectively analyzed 646 admitted from June 2021 May 2022 Medical Oncology Service at La Paz University (Madrid, Spain). Results:...

We present a clinical case of solitary fibrous pleural tumor (TFSP) with abnormal behavior due to its high aggressiveness and poor short-term prognosis, where an ALK translocation was identified. TFSP is infrequent tumor, estimated incidence around 8 per 100,000 inhabitants few cases reported in the literature. The most common that it neoplasm benign behavior, debut as localized mass whose treatment choice surgical resection. All data literature contrast our experience, which we report...

Abstract Purpose : Uncertainty surrounding entails significant psychological distress.The aims were to evaluate the incidence of distress at diagnosis advanced cancer and analyze whether relationship between illness uncertainty can be mediated by coping strategies. Methods A multicenter, prospective,cross-sectional study was conducted in 15 medical oncology departments Spain. Individuals with unresectable completed questionnaires on (Michel Illness Scale, MUIS), strategies (Mental Adjustment...