Mihaela Paula Toader

ORCID: 0000-0002-9838-836X
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About
Contact & Profiles
Research Areas
  • Oral Health Pathology and Treatment
  • Autoimmune Bullous Skin Diseases
  • Dermatology and Skin Diseases
  • Psoriasis: Treatment and Pathogenesis
  • Skin Diseases and Diabetes
  • Head and Neck Cancer Studies
  • Oral and Maxillofacial Pathology
  • Urticaria and Related Conditions
  • Dermatologic Treatments and Research
  • Oral and gingival health research
  • Acne and Rosacea Treatments and Effects
  • Cutaneous Melanoma Detection and Management
  • Dermatological and COVID-19 studies
  • Asthma and respiratory diseases
  • NF-κB Signaling Pathways
  • Diet and metabolism studies
  • Retinoids in leukemia and cellular processes
  • Parvovirus B19 Infection Studies
  • Contact Dermatitis and Allergies
  • Linguistics and Discourse Analysis
  • Bariatric Surgery and Outcomes
  • Salivary Gland Disorders and Functions
  • Female Genital Mutilation/Cutting Issues
  • Eosinophilic Esophagitis
  • Ocular Oncology and Treatments

Grigore T. Popa University of Medicine and Pharmacy
2005-2025

Institutul de Urgenţă pentru Boli Cardiovasculare "Prof.Dr. C.C. Iliescu"
2025

Clinical Emergency Hospital Bucharest
2022-2023

Spitalul Clinic Judeţean de Urgenţe "Sf. Spiridon" Iaşi
2019-2021

Amita Health St. Mary's Hospital
2019-2021

Erosive oral lichen planus (EOLP) represents a significant challenge in dental and medical management due to its chronic inflammatory nature, painful symptoms, impact on quality of life. This study aims evaluate the current diagnostic approach with novel non-invasive techniques, such as dermoscopy, also landscape treatment options for EOLP, focusing efficacy, safety, challenges that it present clinical practice. Through comprehensive literature review, we explored use topical...

10.3390/diagnostics14070692 article EN cc-by Diagnostics 2024-03-26

Background and Objectives: Oral cancer remains a critical global health concern, with oral squamous cell carcinoma (OSCC) being the most prevalent form. potentially malignant disorders (OPMDs), such as leukoplakia (OLK), lichen planus (OLP), actinic cheilitis (AC), often precede OSCC. Identifying reliable biomarkers is vital for assessing transformation risk. The present study aimed to evaluate immunohistochemical expression of differentiated embryonic chondrocyte 1 (DEC1), marker dysplasia...

10.3390/medicina61020251 article EN cc-by Medicina 2025-02-01

Background/Objectives: Atopic dermatitis (AD) and alopecia areata (AA) frequently coexist due to shared immune-mediated mechanisms. Treatments targeting AD, including Janus kinase (JAK) inhibitors dupilumab, may impact AA outcomes in unpredictable ways. This study aims evaluate the effects of advanced therapies on patients with concurrent AD inform treatment strategies. Methods: A retrospective cohort was conducted six diagnosed both AA. included systemic corticosteroids, JAK (baricitinib...

10.3390/diagnostics15050520 article EN cc-by Diagnostics 2025-02-20

Although schwannoma (neurilemmoma) is the most common tumor of peripheral nerve, its low incidence, slow growth and vague symptoms often lead to misdiagnosis or delayed diagnosis. The aim study present a series with large number schwannomas in upper limbs, some very rare occurrence.We report 17 patients mean age 58.5 years limb schwannomas, located on median, ulnar radial nerves, but also posterior interosseous nerve digital collateral nerves. diagnosis was made by clinical examination...

10.3390/diagnostics12061319 article EN cc-by Diagnostics 2022-05-26

Oral lichen planus (OLP) is a complex chronic inflammatory disorder in which autocytotoxic CD8<sup>+</sup> T cells, locally present the affected tissue, induce basal keratinocyte apoptosis, through release of several cytokines, such as interleukin‑6 (IL‑6). IL‑6 proinflammatory cytokine that related to alterations lipid metabolism psoriasis patients. Impaired together with high serum levels triglycerides have been found association OLP. However, correlation between and dyslipidemia has not...

10.3892/etm.2021.10419 article EN Experimental and Therapeutic Medicine 2021-07-13

The study aimed to present the characteristics of three most prevalent oral potentially malignant disorders, leukoplakia, lichen planus (OLP), and actinic cheilitis, using data from 62 patients collected at “Sfântul Spiridon” Emergency Clinical Hospital in Iași, Romania, between January 2015 2023. results revealed a higher prevalence these lesions among older adults, particularly those over 50 years old, significant gender disparity incidence which was more common males (68%). Leukoplakia...

10.62610/rjor.2024.2.16.29 article EN cc-by 2024-03-15

Colchicine has been known and used for over a millennium its anti‑inflammatory properties, being the treatment of choice gout familial Mediterranean fever. A tricyclic alkaloid extracted from herbaceous plant, <em>Colchicum autumnale</em>, colchicine blocks multiple inflammatory pathways, antimitotic antifibrotic action. Although there are insufficient data on beneficial mechanism action, is widely in dermatology, one morbid conditions with more evidence efficacy recurrent aphthous...

10.3892/etm.2021.9712 article EN Experimental and Therapeutic Medicine 2021-01-25

Acne treatment during pregnancy is challenging and should be adapted to the clinical form, lesions severity their impact on patient�s quality of life. The therapeutic decision in such cases need based risk / benefit ratio take into account FDA categories drugs used breastfeeding. Iodine solution a valuable formula useful for different dermatological diseases due its immunomodulatory features. Even actually, it less frequent dermatologic prescriptions, purpose this article highlight benefits...

10.37358/rc.18.9.6530 article EN Revista de Chimie 2018-10-15
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