Yan Leykin

ORCID: 0000-0002-9851-0142
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About
Contact & Profiles
Research Areas
  • Digital Mental Health Interventions
  • Mental Health Research Topics
  • Mental Health Treatment and Access
  • Impact of Technology on Adolescents
  • Suicide and Self-Harm Studies
  • Child and Adolescent Psychosocial and Emotional Development
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Smoking Behavior and Cessation
  • Treatment of Major Depression
  • Attachment and Relationship Dynamics
  • Mental Health via Writing
  • COVID-19 and Mental Health
  • Mobile Health and mHealth Applications
  • Behavioral Health and Interventions
  • Health Literacy and Information Accessibility
  • Patient-Provider Communication in Healthcare
  • Neurological disorders and treatments
  • Social Media in Health Education
  • Health Systems, Economic Evaluations, Quality of Life
  • Ethics in Clinical Research
  • Decision-Making and Behavioral Economics
  • Optimism, Hope, and Well-being
  • Cancer survivorship and care
  • Family Support in Illness
  • Media Influence and Health

University of California, San Francisco
2014-2024

Palo Alto University
2016-2024

Training Programs in Epidemiology and Public Health Interventions Network
2022-2024

Palo Alto Institute
2017-2021

Palo Alto Veterans Institute for Research
2021

San Francisco General Hospital
2010-2020

Global Brain Health Institute
2014

University of Pennsylvania
2007

Worldwide automated Internet health interventions have the potential to greatly reduce disparities. High attrition from is ubiquitous, and presents a challenge in evaluation of their effectiveness. Our objective was evaluate variables hypothesized be related attrition, by modeling predictors secondary data analysis two cohorts an international, dual language (English Spanish) smoking cessation intervention. The were identical except for approach follow-up (FU): one cohort employed only fully...

10.1093/heapro/das029 article EN Health Promotion International 2012-07-10

Concern about the contamination of psychotherapy outcome studies by “allegiance bias”—distortion findings because investigators’ preferences—has led to proposal that date should not be used make inferences relative efficacies psychotherapies. It has also been proposed results from all such adjusted cancel presumed distorting effects allegiances. We argue although much effort devoted towards establishing existence statistical associations between allegiances and outcomes, causal...

10.1111/j.1468-2850.2009.01143.x article EN Clinical Psychology Science and Practice 2009-02-18

Abstract Difficulty making decisions is one of the symptoms depressive illness. Previous research suggests that depressed individuals may make differ from those made by non-depressed, and they use sub-optimal decision-making strategies. For this study we constructed an instrument aims to measure a variety styles as well respondent’s view him or herself decision-maker (decisional self-esteem). These estimates decisional self-esteem were then related symptoms. Depressive symptomatology...

10.1017/s1930297500001674 article EN cc-by-nc-nd Judgment and Decision Making 2010-12-01

Difficulty making decisions is a core symptom of depressive illness, but the nature these difficulties has not been well characterized. The two studies presented herein use same hypothetical scenarios that call for decision. In Study 1, participants were asked to make and explain their in free-response format, as describe prior experiences with similar situations. results suggest those more symptoms are less likely further interests. We also identified several interesting associations...

10.1007/s10608-010-9308-0 article EN cc-by-nc Cognitive Therapy and Research 2010-05-03

Background The past few decades saw considerable advances in research and dissemination of evidence-based psychotherapies, yet available treatment resources are not able to meet the high need for care individuals suffering from depression or anxiety. Blended psychotherapy, which combines strengths therapist-led internet interventions, can narrow this gap be clinically effective efficient, but has rarely been evaluated outside controlled settings. Objective This study effectiveness a blended...

10.2196/18723 article EN cc-by Journal of Medical Internet Research 2020-06-14

Recent research suggests that there may be a reduction in therapeutic response after multiple administrations of antidepressant drug (AD) therapy patients with major depressive disorder. This study assessed the to AD and cognitive (CT) history prior exposures. A sample 240 moderate-to-severe disorder entered randomized controlled trial comparing pharmacotherapy paroxetine CT. Treatment was administered for 16 weeks. History exposure structured interviews, self-report, medical records....

10.1037/0022-006x.75.2.267 article EN Journal of Consulting and Clinical Psychology 2007-01-01

Research on deep brain stimulation (DBS) for treatment‐resistant depression appears promising, but concerns have been raised about the decisional capacity of severely depressed patients and their potential misconceptions research. We assessed 31 DBS research participants with MacArthur Competence Assessment Tool Clinical (MacCAT‐CR), a well‐validated measure, scale to measure therapeutic misconception, which occurs when subjects do not recognize key differences between treatment clinical...

10.1111/j.1749-6632.2012.06596.x article EN Annals of the New York Academy of Sciences 2012-07-19

10.1016/j.jad.2017.12.085 article EN publisher-specific-oa Journal of Affective Disorders 2018-01-03

<sec> <title>BACKGROUND</title> Most patients are not at elevated risk for suicide and active interview assessment of may be reasonable. </sec> <title>OBJECTIVE</title> This paper describes passive monitoring factors from (a) text conversations with the AI system or (b) medical history events reported to system. We report relationship between number replicate judgment two experts regarding suicide. <title>METHODS</title> The adequacy was assessed by agreement in classification LLM a trained...

10.2196/preprints.75272 preprint EN 2025-03-31

Background The number of individuals looking for health information on the Internet continues to expand. purpose this study was understand prevalence major depression among English-speaking worldwide online. Methods An automated online Mood Screener website created and advertised via Google AdWords, 1 year. Participants (N = 24,965) completed a screening measure received feedback based their results. were then invited participate in longitudinal mood study. Results Of 24,965 who screening,...

10.1002/da.20848 article EN Depression and Anxiety 2011-06-16

Background: Internet interventions have the potential to address many of health problems that produce greatest global burden disease. We present a study illustrating this potential. The Spanish/English San Francisco Stop Smoking site, which yielded quit rates 20% or more at 12 months in published randomized controlled trials (RCTs), was modified make it accessible Spanish- and English-speaking smokers 18 years age older anywhere world. Objective: To illustrate designed conduct RCTs can be...

10.2196/jmir.1852 article EN cc-by Journal of Medical Internet Research 2012-06-27

Background Personal health records (PHR) may improve patients' by providing access to and context for information. Among patients receiving care at a safety-net HIV/AIDS clinic, we examined the hypothesis that mental (MH) or substance use (SU) condition represents barrier engagement with web-based information, as measured consent participate in trial provided personal general (non-PHR) information portals completion of baseline study surveys posted there. Methods Participants were...

10.1371/journal.pone.0031888 article EN cc-by PLoS ONE 2012-02-20

Untreated depression remains one of the largest public health concerns. However, barriers such as unavailability mental providers and high cost services limit number people able to benefit from traditional treatments. Though unsupported Internet interventions have proven effective at bypassing many these given their reach scalability, attrition has been an ongoing concern. Microinterventions, or ultra-brief online tools meant produce a rapid improvement in mood, may offer way provide...

10.1016/j.invent.2017.08.004 article EN cc-by-nc-nd Internet Interventions 2017-09-02

Background: Google AdWords, the placement of sponsored links in search results, is a potent method recruitment to Internet-based health studies and interventions. However, performance AdWords varies considerably depending on language location target audience. Objective: Our goal was describe differences when recruiting participants same study conducted four languages determine whether campaigns can be optimized order increase while decreasing costs. Methods: were used recruit Mood Screener,...

10.2196/jmir.2986 article EN cc-by Journal of Medical Internet Research 2014-01-20

Background Adherence to self-guided interventions tends be very low, especially in people with depression. Prior studies have demonstrated that enhancements may increase adherence, but little is known about the efficacy of various comparison to, or combination with, one another. Objective The aim our study test whether 3 enhancements—facilitator contact (FC), an online discussion board, and virtual badges (VB)—alone, combination, improve adherence a self-guided, web-based intervention for We...

10.2196/25922 article EN cc-by Journal of Medical Internet Research 2021-05-24
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