A5007308108- Head and Neck Cancer Studies
- Cervical Cancer and HPV Research
- Tracheal and airway disorders
- Meningioma and schwannoma management
- Lymphadenopathy Diagnosis and Analysis
- Facial Nerve Paralysis Treatment and Research
- Salivary Gland Tumors Diagnosis and Treatment
- Neurofibromatosis and Schwannoma Cases
- Radiomics and Machine Learning in Medical Imaging
- Sarcoma Diagnosis and Treatment
- Dysphagia Assessment and Management
- Esophageal and GI Pathology
- Viral Infections and Outbreaks Research
- Pneumothorax, Barotrauma, Emphysema
- Medical Education and Admissions
- Urban Agriculture and Sustainability
- Lung Cancer Treatments and Mutations
- Medicinal Plants and Bioactive Compounds
- Thyroid and Parathyroid Surgery
- Frailty in Older Adults
- Vascular Tumors and Angiosarcomas
- Cerebrospinal fluid and hydrocephalus
- Ferroptosis and cancer prognosis
- Nigella sativa pharmacological applications
- Congenital Ear and Nasal Anomalies
University of California, Los Angeles
2020-2024
Dartmouth–Hitchcock Medical Center
2024
APLA Health
2024
University of Nevada, Reno
2019-2020
Thyroid cancer presents significant diagnostic challenges due to its complex anatomy and diverse tissue types. This study leverages Dynamic Optical Contrast Imaging (DOCI), a label-free, real-time imaging technology, with machine learning enhance tumor detection segmentation. Using 23 DOCI filters, we applied Principal Component Analysis (PCA) for dimensionality reduction, k-nearest neighbors (k-NN) classification, U-Net models The approach achieved high accuracy in distinguishing types, PCA...
Objective To validate the efficacy of a virtual, interdisciplinary workshop in improving HPV knowledge, and vaccination practices among primary care dental trainees. Methods A virtual platform was utilized to hold educational workshops with Online surveys were distributed before after 1‐h interactive workshop, led by otolaryngology residents. Surveys included workshop's impact on (a) knowledge HPV‐associated oropharyngeal squamous cell carcinoma (OPSCC) (b) affecting change practices. The...
Anaplastic thyroid cancer (ATC) is the most aggressive and fatal malignancy. Currently, there still exists a paucity of literature studying relationship between available ATC-targeted therapy, immunotherapy, survival. We aim to investigate how systemic therapies affect survival outcomes in ATC.
Abstract Objective To investigate the state and trajectory of gender, racial, academic authorship diversity in otolaryngology clinical trial literature over past 2 decades. Study Design Bibliometric analysis. Setting Otolaryngology literature. Methods Clinical trials published 9 major journals between 2000 2020 were included. The race, seniority first, senior, corresponding authors recorded for each trial. Multivariable regression models assessed temporal time disparity citations across...
The aim of the study was to present a case mixed olfactory neuroblastoma (ONB) and carcinoma, an extremely rare tumor with only few cases in published literature.An otherwise healthy 27-year-old male presented sinus complaints, headache, unilateral eye discharge. Imaging endoscopy revealed mass presumed represent juvenile nasopharyngeal angiofibroma. Unexpectedly, final pathology report high grade ONB carcinoma. This is sixth youngest documented patient carcinoma.Physicians should remain...
ABSTRACT Objective: The authors aim to demonstrate that the current drive-through testing model at a health district was improved in certain parameters compared with previous protocol, and provide methodology of for other coronavirus disease (COVID-19) sites potentially emulate. Methods: Initially, small site constructed converted tuberculosis clinic, but due an increase needs, expanded point screening (POST) system developed event center parking lot administer tests higher volume patients....
The authors obtained curriculum needs analysis data from second-year medical students and compared these with nonpsychiatrist physicians psychiatrists. All groups felt that interviewing skills, the doctor-patient relationship, managing dying patient, evaluation of suicidal patients were important topics. gave psychological testing, behavior modification, mental retardation, psychoanalytic theory lowest teaching priority. a higher rating to all topics than did other groups. suggest this kind...
Ectopic thyroid tissue can deposit anywhere in the body. There are several cases reporting papillary carcinoma (PTC) arising from ectopic tissues; however, these largely presented with primary PTC within native gland as well. Alternatively, some report of found solely an thyroglossal duct cyst, but reports isolated malignancy other types normal sparse throughout literature. Here, we present unusual case midline anterior neck that does not appear to be consistent a accompanied by completely...
This study aimed to assess if
Abstract Background Cutaneous angiosarcoma is an aggressive tumor commonly found in the head and neck region. There no consensus regarding definitive treatment for angiosarcoma. Methods This was a retrospective chart review that evaluated 64 patients from 1983 to 2019. Demographic clinical variables were examined impact on recurrence using time overall survival Kaplan–Meier curves. Results Average age at diagnosis 71 (32–95) years, with 2.8 male: female ratio. Surgery utilized 62% of...
Salivary gland choristoma is an extremely rare middle ear mass and hypothesized to be caused by second branchial arch developmental anomalies. We present a 14-year-old girl with Dandy–Walker syndrome conductive hearing loss. Middle exploration revealed large absent incus stapes displaced facial nerve. The was completely excised histological confirmation of salivary choristoma. Her improved bone-anchored aids (BAHA). As nerve involvement common, physicians should consider partial excision...
Positive surgical margins in head and neck cancers (HNC) are associated with poor survival. Standard frozen section analysis for intraoperative assessment of is limited by processing time sampling error. Optical imaging technologies may address these limitations. We identified the following techniques a literature search optical modalities detection tumor margins: autofluorescence imaging, dynamic contrast coherence tomography, narrow band hyperspectral Raman spectroscopy, near-infrared...
Dynamic optical contrast imaging (DOCI) is an method utilizing fluorescence lifetime that our team has developed for identification of margins in head & neck mucosal malignancies. In this paper we demonstrate the first utilization DOCI cutaneous melanoma. We utilized both a 530/30nm band pass filter, as well 400nm long filter to capture autofluorescence tissue fluorophores, after excitation with 365nm wide field LED light source. Imaging was captured, processed via established protocol...
Abstract Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide with approximately 550,000 new cases diagnosed each year. The oropharynx one of sites occurrence, disease in this region often presents palatine tonsil, followed by base tongue soft palate. Human papilloma virus (HPV) a cause HNSCC, giving rise to distinct subset tumors different clinical presentation, course, response treatment. In order further characterize HPV+ HNSCC their therapy response, we...
Abstract The study aims to establish a high throughput ex vivo organoid-based drug screening platform for head and neck squamous cell carcinoma (HNSCC) investigate interactions between radiotherapy different chemotherapies or targeted therapy agents ultimately provide functional precision medicine therapeutic suggestions. HNSCC is the sixth most common cancer worldwide. Both HPV+ HPV- cancers can be treated with surgery, radiotherapy, chemotherapy, combination of these. Cetuximab currently...
The Risk Analysis Index (RAI) score is a screening tool to assess patient frailty. It has been shown be predictive of postoperative outcomes and mortality in orthopedic, urologic, neurosurgical populations. We sought evaluate the ability RAI for surgical an otolaryngology population.
Abstract BACKGROUND Glioblastoma (GBM) is the most common primary brain malignancy in adults. Standard of care (SOC) for suspected GBM begins with maximal safe resection followed by adjuvant radiotherapy and temozolomide, maintenance temozolomide. Imvax has utilized its Goldspire™ platform to create IGV-001, an autologous biologic-device combination product treatment newly diagnosed (ndGBM). IGV-001 consists tumor cells antisense oligonucleotide against IGF-1R mRNA (IMV-001), irradiated...
Abstract Background Intracranial schwannomas are most commonly associated with the vestibulocochlear nerve, often leading to hearing loss, tinnitus, and vestibular dysfunction. Much less often, a schwannoma can arise from trigeminal nerve which lead facial pain, numbness, weakness. Purpose We explored case of patient an magnetic resonance imaging (MRI)-confirmed that was mistaken for because myriad ipsilateral symptoms. Research Design This is retrospective chart review study, no statistics...