A5053216293- Microtubule and mitosis dynamics
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Sedative Agents
- Photosynthetic Processes and Mechanisms
- Antiplatelet Therapy and Cardiovascular Diseases
- Renal function and acid-base balance
- Anesthesia and Pain Management
- Intensive Care Unit Cognitive Disorders
- Electrolyte and hormonal disorders
- Venous Thromboembolism Diagnosis and Management
- Respiratory Support and Mechanisms
- Plant nutrient uptake and metabolism
- Dental Anxiety and Anesthesia Techniques
- Cellular transport and secretion
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Pneumothorax, Barotrauma, Emphysema
- Retinoids in leukemia and cellular processes
- Electroconvulsive Therapy Studies
- Atrial Fibrillation Management and Outcomes
- Potassium and Related Disorders
- Cardiac and Coronary Surgery Techniques
- Photodynamic Therapy Research Studies
- Burn Injury Management and Outcomes
- Cancer, Hypoxia, and Metabolism
- Genetics, Aging, and Longevity in Model Organisms
Kobe University Hospital
2017-2025
Kobe University
2021-2022
Fukuyama City Hospital
2012-2016
National Cerebral and Cardiovascular Center
2012
Microtubules are dynamic polymers consisting of αβ-tubulin heterodimers. The initial polymerization process, called microtubule nucleation, occurs spontaneously via αβ-tubulin. Since a large energy barrier prevents nucleation in cells, the γ-tubulin ring complex is recruited to centrosome overcome barrier. However, considerable number microtubules can polymerize independently various cell types. Here, we present evidence that minus-end-binding calmodulin-regulated spectrin-associated protein...
Under general anesthesia, lidocaine shortens the onset time of vecuronium but it does not affect that rocuronium. We suspected dose rocuronium used in previous reports, 0.6 mg/kg, was too high to detect any difference due lidocaine's effect. investigated effects 1.5 mg/kg on time, 50% depression 100% and duration action 0.4 Sixty adult patients who underwent elective operation under anesthesia without tracheal intubation were randomly divided into two groups: including a group (LG) placebo...
Abstract Background Although 5-aminolevulinic acid is useful for the photodynamic diagnosis of bladder tumors, it often causes severe intraoperative hypotension. We report a case postoperative cardiac arrest in addition to hypotension, probably owing use acid. Case presentation An 81-year-old Japanese man was scheduled undergo transurethral resection tumor. The patient took orally 2 hours before entering operating room. After induction anesthesia, his blood pressure decreased 47/33 mmHg....
Kinesin superfamily proteins are microtubule-based molecular motors driven by the energy of ATP hydrolysis. Among them, kinesin-4 family is a unique motor that inhibits microtubule dynamics. Although mutations cause several diseases, its mechanism unclear because difficulty visualizing high-resolution structure working at plus-end. Here, we report KLP-12, C. elegans ortholog KIF21A and KIF21B, essential for proper length control axons, domain represses polymerization in vitro. The crystal...
No consensus exists whether to continue or withdraw aspirin therapy perioperatively in patients undergoing major laparoscopic abdominal surgery. To investigate preoperative continuation of increases blood loss and associated morbidity during cholecystectomy colorectal cancer resection, we compared duration surgical procedures, amount intraoperative loss, rate transfusion, length postoperative stay, conversion open surgery, reoperation within 48 hours between with without preoperatively....
Abstract Microtubules are dynamic polymers consisting of αβ-tubulin heterodimers. The initial polymerization process, called microtubule nucleation, occurs spontaneously via αβ-tubulin. Since a large energy barrier prevents nucleation in cells, the γ-tubulin ring complex is recruited to centrosome overcome barrier. However, detachment considerable number microtubules from known contribute fundamental processes cells. Here, we present evidence that minus-end-binding calmodulin-regulated...
Introduction: Abdominal aortic aneurysm (AAA) has been traditionally managed with open repair and the indication of endovascular remains to be limited for considerable cases AAA. Postoperative care including pain relief early recovery as well stable hemodynamic control are essential after Hypothesis: We hypothesize that oral clonidine premedication reduces postoperative establishes postoperatively. Methods: Consecutive twenty-three ASA Grade 2-3 patients scheduled elective AAA, were assigned...
Abstract Kinesin superfamily proteins are microtubule-based molecular motors driven by the energy of ATP hydrolysis. Among them, kinesin-4 family is a unique motor that inhibits microtubule dynamics. Although mutations cause several diseases, its mechanism unclear because difficulty visualizing high-resolution structure working at plus-end. Here, we report KLP-12, C. elegans ortholog KIF21A and KIF21B, essential for proper length control axons, domain represses polymerization in vitro . The...