A5031265819- Bladder and Urothelial Cancer Treatments
- LGBTQ Health, Identity, and Policy
- Urological Disorders and Treatments
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Urinary and Genital Oncology Studies
- Urinary Bladder and Prostate Research
- Ureteral procedures and complications
- Sexual Differentiation and Disorders
- Pelvic floor disorders treatments
- Sexual function and dysfunction studies
- Genital Health and Disease
- Reproductive Health and Technologies
- Tissue Engineering and Regenerative Medicine
- Potato Plant Research
- Medical and Health Sciences Research
- Plant nutrient uptake and metabolism
- Agriculture, Plant Science, Crop Management
- Sexuality, Behavior, and Technology
- Plant Pathogens and Resistance
- Environmental Science and Technology
- Agronomic Practices and Intercropping Systems
- Glycosylation and Glycoproteins Research
- Frailty in Older Adults
- Body Image and Dysmorphia Studies
Essen University Hospital
2015-2025
Deutschen Konsortium für Translationale Krebsforschung
2021-2024
Klinik und Poliklinik für Urologie
2014-2024
German Cancer Research Center
2024
Servier (Germany)
2022
University of Duisburg-Essen
2010-2021
University of Kassel
2006-2017
University of Utah
2016
Lake City VA Medical Center
2016
Deutsches Herzzentrum der Charité
2006-2014
The frequency of gender identity disorder is hard to determine; the number reassignment operations and court proceedings in accordance with German Law on Transsexuality almost certainly do not fully reflect underlying reality. There have been only a few studies patient satisfaction male-to-female surgery.254 consecutive patients who had undergone surgery at Essen University Hospital's Department Urology retrospectively filled out questionnaire about their subjective postoperative...
Background: Transgender individuals experience a high level of distress over the lifespan and are at higher risk experiencing mental health conditions.Objective: The present study mainly aimed to investigate complex relationship between early maladaptive schemas (EMSs), adverse childhood experiences conditions in adulthood among transgender individuals.Method: 220 participants completed an anonymous online assessing sociodemographic medical status, adversity (CTQ), EMSs (YSQ-S3), specific...
Male-to-Female (MtF) gender affirmation surgery (GAS) comprises the creation of a functional and aesthetic perineogenital complex. This study aimed to evaluate effect GAS on sexuality. We retrospectively surveyed all 254 MtF transsexual patients who had undergone with penile inversion vaginoplasty at Department Urology, University Hospital Essen, Germany, between 2004 2010. In total, we received 119 completed questionnaires after median 5.05 years since surgery. Of participants, 33.7%...
Objective To describe the surgical outcomes of ileal vaginoplasty in transgender women and patients with disorders sex development ( DSD ). Patients Methods Transgender , who underwent at VU University Medical Center Amsterdam, Hospital Trieste, Essen, Belgrade Hospital, were retrospectively identified. A chart review was performed, recording technique, intraoperative characteristics, complications, re‐operations. Results We identified a total 32 (27 five non‐transgender), median (range) age...
Abstract Background The extent of pelvic lymphadenectomy (PLND) as part radical cystectomy (RC) for bladder cancer (BC) remains unclear. Sentinel‐based and lymphangiographic approaches could lead to reduced morbidity without sacrificing oncologic safety. Objective To evaluate the feasibility diagnostic value fluorescence‐guided template sentinel region dissection (FTD) using a handheld near‐infrared fluorescence (NIRF) camera in open cystectomy. Design, Setting, Participants After...
Hyaluronan (HA) is a carbohydrate of the extracellular matrix with tumor promoting effects in variety cancers. The present study addressed role HA for progression and prognosis human bladder cancer by studying expression function HA-related genes. MethodsTissue samples 120 patients different stages transitional cell cancer, who underwent surgical treatment at University Hospital Essen were analysed. mRNA-expression levels synthases (HAS1-3) HA-receptors (RHAMM CD44) evaluated real time...
The Polo-like Kinase 1 (PLK1) protein regulates cell cycle progression and is overexpressed in many malignant tissues. Overexpression associated with poor prognosis several cancer entities, whereby expression of PLK1 shows high inter-individual variability. Although extensively studied, not much known about the genetic variability gene. function corresponding gene could be influenced by genomic variations. Hence, we investigated for functional polymorphisms. Such polymorphisms useful to...
•First patient-reported HRQoL and post-authorisation efficacy safety data from German mCRC patients receiving FTD/TPI.•Results were consistent with results of pivotal phase III other studies.•FTD/TPI prolonged survival delayed progression manageable toxicity profile.•Treatment FTD/TPI was associated maintained HRQoL. IntroductionTrifluridine/tipiracil (FTD/TPI) improved both overall progression-free (OS, PFS) pre-treated metastatic colorectal cancer (mCRC) in the RECOURSE trial. However,...
To achieve long-term improvement in health care of transgender women, it is necessary to analyze all aspects gender-confirming surgery, especially the relation risks and benefits occurring these procedures. While there are many studies presenting data on urologic part just few about complications satisfaction with breast augmentation.This a retrospective study using parts BREAST-Q Augmentation Questionnaire additional questions for symptoms capsular contracture re-operations analyzing...
Chemotherapy resistance is a main cause of therapeutic failure and death in bladder cancer. With the approval immune checkpoint inhibitors, prediction platinum treatment became great clinical importance. Matrix metalloproteinase-7 (MMP-7) was shown to be involved cisplatin resistance. Therefore, tissue circulating MMP-7 levels were evaluated 124 cancer patients who received postoperative platinum-based chemotherapy. Tissue analyzed by immunohistochemistry 72 formalin-fixed, paraffin-embedded...
The main objective of gender reassignment surgery (GRS) in male to female (MtF) transgender people is create a functional and aesthetic vagino-clitoral complex. Here we report on modified preparation the neurovascular bundle (NVB).Between May 2011 September 2014, 96 consecutive MtF patients underwent GRS at our department. Sensitivity neoclitoris was assessed afterwards. Results were compared with historical cohort from department (2004-2010, n = 119) which perioperative treatment same...
Abstract Factorial field trials were carried out on an experimental farm near Kassel, Germany, in two consecutive seasons (2003 and 2004) order to examine the impact of leguminous cereal preceding crops (i) soil N availability under subsequent potatoes (ii) effect crop pre‐sprouting seed tubers development, uptake, utilization efficiency total size‐graded tuber yields relevant for processing into either crisps or French fries. In addition, approach analyse complex experiments using mixed...