A5041553347- Cardiac tumors and thrombi
- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Angiogenesis and VEGF in Cancer
- Advanced MRI Techniques and Applications
- Cardiac Structural Anomalies and Repair
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiovascular and Diving-Related Complications
- Congenital heart defects research
- Congenital Heart Disease Studies
- Tracheal and airway disorders
- Lymphatic System and Diseases
- Vascular anomalies and interventions
- Cancer Treatment and Pharmacology
- Cardiac, Anesthesia and Surgical Outcomes
- Apelin-related biomedical research
- Coronary Interventions and Diagnostics
- Global Health and Surgery
- Sarcoma Diagnosis and Treatment
- Cardiovascular Health and Disease Prevention
- Global Health Workforce Issues
- Protease and Inhibitor Mechanisms
- Coronary Artery Anomalies
- Tissue Engineering and Regenerative Medicine
New Tokyo Hospital
2016-2023
University of Tsukuba
2005-2012
Hitachi General Hospital
2008
NorthEast Regional Epilepsy Group
2008
Three-dimensional speckle tracking imaging (3D-STI) has been introduced to assess regional left ventricular (LV) myocardial function. This study was designed validate LV strain measurements by 3D-STI against data obtained sonomicrometry.In each of 10 anesthetized sheep, sonomicrometry crystals were implanted on the endocardium and epicardium at basal, mid, apical anterior lateral walls. sets from approach a frame rate approximately 30 frames/s. Segmental longitudinal (LS), radial (RS),...
Human placenta is an attractive source of mesenchymal stem cells (MSC) for regenerative medicine. The cell surface markers expressed on MSC have been proposed as useful tools the isolation from other populations. However, correlation between expression and ability to support tissue regeneration in vivo has not well examined. Here, we established several lines human examined their differentiate toward lineages. We found that CD349/frizzled-9, a receptor Wnt ligands, was positive...
An isolated coronary sinus (CS) atrial septal defect (ASD) is defined as a CS unroofed in the terminal portion without persistent left superior vena cava or other anomalies. This rare and part of wide spectrum syndrome (URCS). Recently, several reports have described this finding. The database New Tokyo Hospital was searched to determine incidence defect. Additionally, raise awareness condition, findings from five patients with ASD who underwent surgical repair at are discussed.The were...
Abstract Background: Surgical repair for hypoplastic aortic arch in neonates carries a substantial risk of recurrent obstruction. Simple anastomosis is not always solution cases extended hypoplasia. We present our modified technique augmented with subclavian flap aortoplasty. Method: describe two neonates: interrupted and transverse hypoplasia associated coarctation, who underwent modification Results: The patients recovered without any pressure gradient at the anastomotic site....
Introduction: Contrast-induced nephropathy (CIN) is a serious complication associated with angiography and interventional angioplasty. Increased doses of contrast medium are major risk factor CIN. It was assumed that the occurrence CIN could be decreased by reducing dose medium. We investigated effects new high resolution angiographic system on application diluted Method: Contrast to 32% (a stock solution), 24%, 16%, 12%, 8%, 4%. Angiography hindlimb in rats using synchrotron radiation HARP...
Abstract Background : Isolated coronary sinus atrial septal defect (ASD) is defined as a unroofed in the terminal portion without persistent left superior vena cava and other anomalies. This rare part of wide spectrum syndromes. Recently, several reports have described this finding. We searched hospital’s database to determine incidence defect, raise awareness condition, we discussed findings from five patients with ASD who underwent surgical repair. Case presentation: The were three women...
心臓原発腫瘍は稀な疾患であり，組織学的には粘液腫が最も多く，ついで乳頭状弾性線維腫（Papillary fibroelastoma : PFE）が多いと言われている．今回われわれは，左房粘液腫と大動脈弁PFEを同時に認めた1例を経験したので報告する．症例は77歳女性．夜間胸痛で前医を受診され，冠動脈CTにて左房粘液腫を指摘され，当科紹介となった．心臓超音波検査にて左房内に20 mm大の可動性の乏しい腫瘤を認め，待機手術の方針となった．術中の経食道超音波検査（Transesophageal echocardiography...
Purpose: The outcome from therapeutic angiogenesis in diabetes mellitus (DM) is not satisfactory compared with non‐DM patients. In diabetes, protein kinase C (PKC) activated according to intracellular high glucose concentration. And PKC closely related progression of diabetic microangiopathy. Recently, it was reported that blockade brought about beneficial effects on From these backgrounds, we investigated effect inhibitor (bisindolylmaleimide: Bis) mice. Methods: Type I induced by...
Purpose: The importance of non‐invasive measuring vascular endothelial function is widely recognized. However, it has not been established in mice as far we know. From this background, tried to establish a new method measure through nitric oxide (NO) mediated vasodilation. Method: Mouse hindlimb (n = 6) was compressed for short time (30 seconds) and released immediately. arterial blood flow measured continuously using laser Doppler meter at arcus plantaris. Result: Reactive hyperemia...
Purpose: Degeneration of pericytes and acellular capillaries are increased in the feet human diabetic patients. Selective loss adhesion pericyte to endothelial cell is known early event microangiopathy. In diabetes, inflammation due dysfunction augmented. Cilostazol, a PDE III inhibitor, reported reduce oxidative stress Based on these findings, we investigated effect cilostazol endothelial/pericyte ischemic hindlimb mice. Method: Type I diabetes was induced by intraperitoneal administration...
Abstract Background: Isolated coronary sinus atrial septal defect (ASD) is defined as a unroofed in the terminal portion without persistent left superior vena cava and other anomalies. This rare part of wide spectrum syndromes. Recently, several reports have described this finding. We searched hospital’s database to determine incidence defect, raise awareness condition, we discussed findings from five patients with ASD who underwent surgical repair. Case presentation: The were three women...