A5003699311- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Congenital Heart Disease Studies
- Aortic Disease and Treatment Approaches
- Cardiovascular Function and Risk Factors
- Cardiac pacing and defibrillation studies
- Aortic aneurysm repair treatments
- Cardiac Imaging and Diagnostics
- Peripheral Artery Disease Management
- Cardiac and Coronary Surgery Techniques
- Infectious Aortic and Vascular Conditions
- Atrial Fibrillation Management and Outcomes
- Pericarditis and Cardiac Tamponade
- Pulmonary Hypertension Research and Treatments
- Coronary Interventions and Diagnostics
- Vascular anomalies and interventions
- Mechanical Circulatory Support Devices
- Angiogenesis and VEGF in Cancer
- Cardiac, Anesthesia and Surgical Outcomes
- Trauma Management and Diagnosis
- Vascular Procedures and Complications
- Coronary Artery Anomalies
- Cardiac tumors and thrombi
- Cardiac Arrhythmias and Treatments
Kobe City Medical Center General Hospital
2006-2017
Hiroshima Kyoritsu Hospital
2016
Anjo Kosei Hospital
2013
Toyooka Hospital
2003-2013
Aichi Medical University
2013
Nagano Prefecture Forestry Research Center
2012
Hamamatsu Medical Center
2008
Kobe Asahi Hospital
1995-2007
Foundation for Biomedical Research and Innovation
2005
Mie University
2003
Abstract A number of preclinical studies have indicated the therapeutic potential endothelial progenitor cells for vascular regeneration in ischemic diseases. phase I/IIa clinical trial transplantation autologous CD34+ cells, and hematopoietic progenitor-enriched fraction, was performed no-option patients with atherosclerotic peripheral artery disease or Buerger's critical limb ischemia (CLI). were isolated from G-CSF-mobilized apheresis product using a magnetic cell sorting system. (105/kg,...
The management of aortic intramural hematoma (IMH) involving the ascending aorta (type A) has not been well-established. purpose this study was to clarify long-term clinical outcomes patients with type A IMH who were treated medical therapy and timely operation.Clinical data including operative mortality, IMH-related events, survival retrospectively reviewed in 66 IMH, admitted our institution from 1986 2006. Emergent surgical repair performed 16 (24%) because severe complications, whereas...
Background— Although animal studies showed that annular remodeling may be related to the pathogenesis of chronic ischemic mitral regurgitation (CIMR), little was known in humans. A better understanding precise 3D geometry valvular-ventricular complex CIMR is needed devise a surgical technique. The purpose study elucidate patients with using cardiac MRI. Methods and Results— Thirty-eight previous inferior or posterior myocardial infarction were studied. With reconstruction annulus subvalvular...
Background: A prior phase I/IIa clinical trial provided evidence for safety, feasibility and potential efficacy of i.m. injection granulocyte colony-stimulating factor (G-CSF)-mobilized CD34+ cells in patients with critical limb ischemia (CLI). Methods Results: II cell therapy was conducted CLI to explore endpoint selection timing. No-option (n=11) underwent transplantation G-CSF-mobilized isolated by magnetic sorting. Ischemic rest pain scales improved from week 2 vs. baseline (P<0.05)....
The frequency of primary cardiac tumors is rare at about 0.3% by autopsy. Our objective was to investigate the characteristics and locations provide a prognostic analysis in our hospital.We collected data on 95 patients with echocardiographic diagnosis or detection prospective from 1999 2014. median follow-up period 43 months (0.5-183 months).The subjects included 56 men 39 women mean age 65 years. Clinical revealed 61 (64%) secondary metastatic 34 (36%). In patients, 41 (67%) underwent...
Objective The management of asymptomatic severe and very aortic stenosis (AS) remains unestablished. This study aimed to investigate the clinical outcomes versus AS patients. Design A single centre, retrospective cohort study. Patients Methods retrospectively reviewed 108 conservatively treated patients with (a maximal jet velocity ≥4.0 m/s, or mean pressure gradient (MPG) ≥40 mm Hg, an valve area (AVA) <1.0 cm2) 58 ≥5.0 MPG ≥50 Hg AVA <0.6 cm2). Clinical were compared between two groups,...
<h3>Objective</h3> Many patients with aortic stenosis (AS) have coexisting regurgitation (AR). However, few data exist regarding its clinical significance and prognostic value. The aim of this study was to examine the effect concomitant significant AR on outcomes in non-surgically treated severe AS. <h3>Design</h3> A single centre, retrospective cohort study. <h3>Patients methods</h3> We retrospectively reviewed 306 consecutive (age, 72±11 years) AS whom non-surgical management primarily...
The aim of this study is to elucidate the impact preoperative and postoperative pulmonary hypertension (PH) on long-term clinical outcomes after mitral valve repair for degenerative regurgitation.A total 654 patients who underwent regurgitation between 1991 2010 were retrospectively reviewed. Patients divided into PH(+) group (137 patients) PH(-) (517 patients). Follow-up was complete in 99.0%. median follow-up duration 7.5 years.Patients older, more symptomatic had higher tricuspid grade....
Background: Limited data are available for gender-based differences in patients undergoing coronary revascularization. This study aimed to identify risk factor profiles and outcomes among Japanese Methods Results: The subjects consisted of 2,845 women 6,843 men who underwent first percutaneous intervention or artery bypass grafting 2000-2002. outcome measures were all-cause death, major adverse cardiovascular events (MACE) as the composite myocardial infarction stroke, any females older than...
Background: Atopic dermatitis (AD) is a common skin condition in which Staphylococcus (S.) aureus can cause native valve destruction patients with infective endocarditis (IE). The aim of this study was to determine the early and late outcomes IE AD. Methods Results: medical records AD who presented between January 1997 September 2010 were analyzed retrospectively. compared those without mean follow-up period 5.5±3.4 years. incidence among 6.7% they significantly younger than (28.4 years vs....
Purpose: We investigated the long-term outcomes of suture/ring tricuspid valve annuloplasty for functional regurgitation associated with degenerative mitral regurgitation.Methods: retrospectively reviewed patients who underwent flexible ring (n = 120) or suture 42) concomitant surgery (mean follow-up duration, 5.3 ± 5.1 years).Results: The mean age was 62.5 13.1 years. Thirty-day mortality zero in group, and 0.8% group. Tricuspid grade at discharge lower group ( p 0.002). No difference...
Background: We reviewed our 20-year experience of mitral valve (MV) repair for degenerative regurgitation (MR) and analyzed the mechanisms risk factors reoperation. Methods Results: Six hundred fifty-four patients who underwent MV MR between 1991 2010 were retrospectively reviewed. The mean follow-up duration was 7.5±4.9 years. Late echocardiography obtained at a fixed schedule. Standard procedures resection suture posterior prolapse, artificial chordal reconstruction anterior prolapse...
Three-dimensional echocardiography (3DE) can simultaneously assess left ventricular (LV) regional systolic motion and global LV mechanical dyssynchrony.We used 3DE to measure dyssynchrony index (SDI) (standard deviation of the time from cardiac cycle onset minimum volume in 17 segments) 100 patients analyzed association SDI with other parameters for function or dyssynchrony. Eighteen who underwent resynchronization therapy (CRT) were also evaluated at 6 months after CRT, baseline tissue...