Wenying Zhang

ORCID: 0000-0002-9926-4115
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About
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Research Areas
  • Structural Load-Bearing Analysis
  • Plant Gene Expression Analysis
  • Plant Stress Responses and Tolerance
  • Plant biochemistry and biosynthesis
  • Wheat and Barley Genetics and Pathology
  • Lymphoma Diagnosis and Treatment
  • CAR-T cell therapy research
  • Chronic Lymphocytic Leukemia Research
  • Plant Molecular Biology Research
  • Plant responses to water stress
  • Structural Engineering and Vibration Analysis
  • Seismic Performance and Analysis
  • Plant-Microbe Interactions and Immunity
  • Plant Reproductive Biology
  • Photosynthetic Processes and Mechanisms
  • Environmental remediation with nanomaterials
  • Structural Behavior of Reinforced Concrete
  • Rice Cultivation and Yield Improvement
  • Crop Yield and Soil Fertility
  • MicroRNA in disease regulation
  • Structural Analysis and Optimization
  • Genetic Mapping and Diversity in Plants and Animals
  • Viral Infectious Diseases and Gene Expression in Insects
  • Lipid metabolism and biosynthesis
  • Plant nutrient uptake and metabolism

Changchun University of Chinese Medicine
2025

Yangtze University
2015-2024

Jilin Engineering Normal University
2019-2024

Beijing University of Technology
2019-2024

University of Chinese Academy of Sciences
2019-2024

Beijing Botanical Garden
2021-2024

Institute of Botany
2021-2024

Zhejiang University
2009-2024

Chinese Academy of Sciences
2017-2024

Changchun Institute of Applied Chemistry
2022-2024

Abstract Owing to the high depth of tissue penetration, non‐invasiveness, and controllability, ultrasound (US)‐mediated sonodynamic therapy (SDT) has shown broad application prospects for tumor treatment. However, electron‐hole separation inefficiency sonosensitizers hypoxia remain two major challenges limiting effect SDT. Here, ultrafine photoetched bismuth vanadate (BiVO 4 ) nanorods modified with DSPE‐PEG 2000 (PEBVO@PEG NRs) were fabricated achieve in situ self‐supply oxygen (O 2...

10.1002/anie.202209484 article EN Angewandte Chemie International Edition 2022-09-09

The desirable curative effect in clinical immunotherapy has been challenging due to the immunosuppressive tumor microenvironment (TME) with high lactic acid (LA) metabolism solid tumors. Although targeting metabolic reprogramming of cells can restore survival and function immune TME, it is also plagued by insufficient immunogenicity. Herein, an activatable immunomodulatory nanoadjuvant CuSe/CoSe2@syrosingopine (CSC@Syro) constructed for simultaneously relieving TME boosting response....

10.1021/jacs.2c12772 article EN Journal of the American Chemical Society 2023-03-23

Abstract Single‐atom nanozyme (SAzyme) has sparked increasing interest for catalytic antitumor treatment due to their more tunable and diverse active sites than natural metalloenzymes in complex physiological conditions. However, it is usually a hard task precisely conduct catalysis at tumor after intravenous injection of those SAzyme with high reactivity. Moreover, the explorations SAzymes anticancer application are still its infancy need be developed. Herein, an situ synthesis strategy Cu...

10.1002/anie.202402397 article EN Angewandte Chemie International Edition 2024-02-23

MicroRNAs (miRNAs) are important regulators of many physiological and pathological processes, including cell proliferation, apoptosis, cycle arrest. In this study, we aimed to investigate the biological role miR-155 in cervical cancer underlying molecular mechanism involved tumorigenesis. The expression human tissues was detected by real-time PCR. MTT assay BrdU incorporation were used measure proliferation cells. Apoptosis cells distribution analyzed flow cytometry. We found that...

10.1007/s13277-014-2479-7 article EN Tumor Biology 2014-08-26

Drought stress is one of the most severe environmental constraints to plant growth and crop productivity. Plant greatly affected by drought stress, plants, survive, adapt this invoking different pathways. Piriformospora indica, a root-colonizing endophytic fungus Sebacinales, promotes confers resistance biotic abiotic stresses, including affecting physiological properties host plant. The strongly colonizes roots maize (Zea mays L.) shoot root under both normal conditions stress. We used...

10.1016/j.cj.2016.10.002 article EN cc-by-nc-nd The Crop Journal 2016-11-12

Arsenic (As) toxicity can be a hazardous threat to sustainable agriculture and human health. Piriformospora indica (P. indica), as beneficial endophytic fungus, is involved in the plant tolerance stressful conditions. Here, biochemical molecular responses of rice plants As (50 μM) phytotoxicity P. inoculation well role improving adaptation stress were evaluated. The results showed that reduced chlorophylls content, chlorophyll fluorescence yield (Fv/Fm), electron transport rate (ETR) growth....

10.1016/j.ecoenv.2020.111793 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2020-12-22

As an endophytic fungus of Sebacinales, Piriformospora indica promotes plant growth and resistance to abiotic stress, including drought. Colonization maize roots promoted the leaf size, root length number tap roots. Under drought seedlings profited from presence performed visibly better than uncolonized controls. To identify genes biological processes involved in promotion tolerance conferred by P. indica, transcriptome colonized was analyzed 0, 6 12 h after stress (20% polyethylene glycol...

10.1080/15592324.2017.1414121 article EN Plant Signaling & Behavior 2017-12-08

The dwarfing gene sdw1 has been widely used throughout the world to develop commercial barley varieties. There are at least four different alleles locus. Mutations in gibberellin 20-oxidase (HvGA20ox2) resulted multiple sdw1.d allele from Diamant is due a 7-bp deletion exon 1, while sdw1.c Abed Denso 1-bp and 4-bp insertion 5' untranslated region. sdw1.a Jotun total of HvGA20ox2 gene. structural changes result lower expression lack sdw1.a. three HvGA20ox genes genome. partial or loss...

10.1186/s12870-016-0964-4 article EN cc-by BMC Plant Biology 2017-01-13

Intracerebral hemorrhage (ICH) induces high mortality and disability. Neuronal death is the principal factor to unfavourable prognosis in ICH. However, mechanisms underlying this association remain unclear. In study, we investigated molecular by which neuronal ferroptosis occurs after ICH whether use of corresponding modulators can inhibit improve early outcomes a rat model. Our findings indicated that Nox4 TF/TfR were upregulated perihematomal tissues rats. Oxidative stress iron overload...

10.1016/j.freeradbiomed.2023.02.015 article EN cc-by-nc-nd Free Radical Biology and Medicine 2023-02-18

Abstract Linalool and caryophyllene are the main monoterpene sesquiterpene compounds in lavender; however, genes regulating their biosynthesis still remain many unknowns. Here, we identified LaMYC7, a positive regulator of linalool biosynthesis, confers plant resistance to Pseudomonas syringae. LaMYC7 was highly expressed glandular trichomes, overexpression could significantly increase contents reduce susceptibility P. syringae Nicotiana. In addition, possessed antimicrobial activity against...

10.1093/hr/uhae044 article EN cc-by Horticulture Research 2024-02-06

Manure application is considered a good way to modify soil structure and hydraulic properties has the potential promote water productivity. Therefore, for improving savings productivity through use of manure as substitute mineral fertilizer worth further exploration in deficit irrigation regions. A field experiment with four regimes types inputs was conducted North China Plain. The included W0 (no irrigation), W1 (irrigation at presowing stage only), W2 jointing stages), W3 presowing,...

10.1016/j.agwat.2024.108731 article EN cc-by-nc-nd Agricultural Water Management 2024-02-29

Pinus taeda is an important forest tree species for plantations because of its rapid growth and high yield oleoresins. Although P. distribute in warm wet southern China, drought, sometime serious long time, often occurs the region. To explore drought tolerance usage beneficial microorganisms, seedlings were planted pots inoculated with root endophytic fungus Serendipita indica finally treated stress 53 d. Metabolome proteome their needles analyzed. The results showed that S. inoculation...

10.3389/fmicb.2024.1294833 article EN cc-by Frontiers in Microbiology 2024-03-15

We have examined the role that transcription factor gut-enriched Krüppel-like (KLF4 or GKLF) plays in activating enterocyte differentiation marker gene intestinal alkaline phosphatase (IAP). A yeast one-hybrid screen was used to identify proteins interacting with a previously identified cis-element (IF-III) located within human IAP promoter. DNA-protein interactions were determined by using EMSA. Northern blot analysis study RNA expression colon cancer RKO cells engineered overexpress KLF4....

10.1152/ajpgi.00203.2003 article EN AJP Gastrointestinal and Liver Physiology 2004-01-01

Abstract Understanding drought-tolerance mechanisms and identifying genetic dominance are important for crop improvement. Setaria italica , which is extremely drought-tolerant, has been regarded as a model plant studying stress biology. Moreover, different genotypes of S. have evolved various drought-tolerance/avoidance that should be elucidated. Physiological transcriptomic comparisons between drought-tolerant cultivar ‘Yugu1’ drought-sensitive ‘An04’ were conducted. had higher yields more...

10.1038/s41598-017-08854-6 article EN cc-by Scientific Reports 2017-08-24

Wheat seed development is an important physiological process of maturation and directly affects wheat yield quality. In this study, we performed dynamic transcriptome microarray analysis elite Chinese bread cultivar (Jimai 20) during grain using the GeneChip Genome Array. Grain morphology scanning electron microscope observations showed that period 11–15 days post-anthesis (DPA) was a key stage for synthesis accumulation starch. Genome-wide transcriptional profiling significance microarrays...

10.1016/j.cj.2016.01.006 article EN cc-by-nc-nd The Crop Journal 2016-02-14

AbstractThe paper presents experimental and numerical investigation of cold-formed steel (CFS)–framed walls sheathed with corrugated sheets. The new wall technology is considered as an alternative shear configuration for midrise buildings at strong earthquake high-wind regions because its attributes noncombustibility higher structural performance than the conventional types. However, design provisions such CFS-framed have not been included in current standards. To establish comprehensive...

10.1061/(asce)st.1943-541x.0001681 article EN Journal of Structural Engineering 2016-10-17
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