A5073773508- Herbal Medicine Research Studies
- Ion channel regulation and function
- Inflammatory Bowel Disease
- Ion Transport and Channel Regulation
- Pharmacological Effects of Medicinal Plants
- Inflammatory mediators and NSAID effects
- Gastrointestinal motility and disorders
- Pancreatic function and diabetes
- Microbial Metabolites in Food Biotechnology
Universidad San Jorge
2016-2019
Jasonia glutinosa is an endemic plant species of the Iberian Peninsula and Southern France traditionally used in infusions as a spasmolytic; this also known "té de roca" (rock tea) but there no scientific evidence about effects plant.To evaluate spasmolytic effect rock tea.We have studied vitro tea extract on rat duodenum spontaneous contractions vivo mice gastrointestinal transit.Rock reduced duodenal smooth muscle, inhibited KCl-induced blocked invoked by both extracellular Ca2+ agonist...
Abstract: The epithelial intermediate-conductance calcium/calmodulin-regulated KCa3.1 channel is considered to be a regulator of intestine function by controlling chloride secretion and water/salt balance. Yet, little known about the functional importance in intestinal epithelium vivo. Our objective was determine impact epithelial-specific inducible overexpression transgene (KCa3.1+) suppression (KCa3.1-) on homeostasis mice. duodenal doxycycline (DOX)-treated KCa3.1+ mice 40-fold above...