A5013026839- Nanoparticle-Based Drug Delivery
- Conducting polymers and applications
- Microfluidic and Bio-sensing Technologies
- Polymer Surface Interaction Studies
- 3D Printing in Biomedical Research
- Luminescence and Fluorescent Materials
- Electrospun Nanofibers in Biomedical Applications
- Supramolecular Self-Assembly in Materials
- Ultrasound and Hyperthermia Applications
- Micro and Nano Robotics
- Analytical Chemistry and Sensors
- Organic Electronics and Photovoltaics
- Metabolism and Genetic Disorders
- Modular Robots and Swarm Intelligence
- Force Microscopy Techniques and Applications
- Pickering emulsions and particle stabilization
- Hemoglobin structure and function
- Lipid Membrane Structure and Behavior
- Photochromic and Fluorescence Chemistry
- Traumatic Ocular and Foreign Body Injuries
- Intraocular Surgery and Lenses
- Protein purification and stability
- Surgical Sutures and Adhesives
- Spectroscopy and Quantum Chemical Studies
- Genetic Neurodegenerative Diseases
Max Planck Institute for Medical Research
2023-2024
Heidelberg University
2023
University of California, Los Angeles
2021
Hasselt University
2016-2020
IMEC
2018-2020
Johannes Gutenberg University Mainz
2018
Max Planck Institute for Polymer Research
2018
Acoustic waves exert forces when they interact with matter. Shaping ultrasound fields precisely in 3D thus allows control over the force landscape and should permit particulates to fall into place potentially form whole objects "one shot." This is promising for rapid prototyping, most notably biofabrication, since conventional methods are typically slow apply mechanical or chemical stress on biological cells. Here, we realize generation of compact holographic demonstrate one-step assembly...
The development of stimuli-responsive nanomaterials, that possess tailored functional properties for the release specific compounds, is particular interest.
The authors report on the effect of ionic strength formation supported vesicle layers anionic phospholipids 1,2-dimyristoyl-sn-glycero-3-phospho-rac-glycerol (DMPG) and dimyristoylphosphatidylserine (DMPS) onto gold. Using quartz crystal microbalance with dissipation monitoring show that adsorption is mainly governed by NaCl concentration, reflecting importance electrostatic interactions in lipids, as compared to zwitterionic 1,2-dimyristoyl-sn-glycero-3-phosphocholine. At low strength, or...
The morphology and release properties of aqueous core nanocapsules for the pH-responsive hydrophilic payload was investigated by systematically varying number biodegradable segments.
Fluorescent conjugated polymers formulated in nanoparticles show attractive properties to be used as bioimaging probes. However, their fluorescence brightness is generally limited by quenching phenomena due interchain aggregation the confined nanoparticle space. In this work, branched polymer networks are investigated a way enhance photoluminescence quantum yield of resulting (CPNs). 1,3,5-Tribromobenzene and 2,2′,7,7′-tetrabromo-9,9′-spirobifluorene chosen branching moieties added 3 or 5...
The lipid organization of microbubbles is important in many applications.
Abstract It is now well‐established that the surface chemistry and “stealth” functionalities such as poly(ethylene glycol) (PEG) chains of nanocarriers play an important role to decrease unspecific protein adsorption opsonizing proteins, increase enrichment specific stealth prolong circulation times nanocarriers. At same time, PEG are used provide colloidal stability for nanoparticles. However, it not clear how chain length density influence keeping at time nanoparticles in a biological...
The extracellular matrix (ECM) plays an immense role in the homeostasis of tissues and organs, can function as a barrier for infectious agents, but is also exploited by pathogens during infection. Therefore, development well-defined 3D ECM models form microcapsules to elucidate interactions between components confinement study disease infectivity important, albeit challenging. Current limitations are mainly attributed lack biocompatible methods production protein-based microcapsules. Herein,...
The creation of whole 3D objects in one shot is an ultimate goal for rapid prototyping, most notably biofabrication, where conventional methods are typically slow and apply mechanical or chemical stress on biological cells. Here, we demonstrate one-step assembly matter to form compact shapes using acoustic forces, which enabled by the superposition multiple holographic fields. technique contactless shown work with solid microparticles, hydrogel beads cells inside standard labware. structures...