A5040308109- Ocular Surface and Contact Lens
- Corneal Surgery and Treatments
- Intraocular Surgery and Lenses
- Surgical Sutures and Adhesives
- Glaucoma and retinal disorders
- Pain Mechanisms and Treatments
- Urticaria and Related Conditions
- Advanced Drug Delivery Systems
- Synthesis and properties of polymers
- Parasitic Infections and Diagnostics
- Corneal surgery and disorders
- Facial Trauma and Fracture Management
- Bee Products Chemical Analysis
- Ocular Infections and Treatments
- Nanoparticle-Based Drug Delivery
- Protist diversity and phylogeny
- Retinal and Macular Surgery
- Ocular Disorders and Treatments
- Echinoderm biology and ecology
- Mast cells and histamine
- Traumatic Ocular and Foreign Body Injuries
Smith-Kettlewell Eye Research Institute
2019-2025
Massachusetts Eye and Ear Infirmary
2019-2025
Harvard University
2019-2025
Boston University
2021
National Eye Institute
2019
To report the outcomes of cyanoacrylate tissue adhesive (CTA) application in corneal thinning and perforation.A retrospective interventional case series 137 patients receiving CTA for perforation 140 eyes between 2001 2018 at a single center was reviewed. Success rate factors associated with glue failure were analyzed.Median age cohort 63 years 69 (50%) women. One hundred fifteen (84%) had least 1 systemic condition, 46 (34%) autoimmune diseases. Eighty-nine (64%) presented 51 (36%)...
Micelles loaded in a photocrosslinkable gelatin based hydrogel as non-invasive suture-free approach for corneal tissue regeneration after injury with infection.
Abstract Introduction: Ocular pain is a common complaint to eye care providers, associated with variety of ocular conditions, among which dry disease (DED) affecting millions people worldwide. Despite being highly prevalent, not managed adequately in the clinic. Objectives: The aim this study was investigate analgesic potential neurokinin-1 receptor (NK1R) antagonism DED. Methods: Dry induced mice, and an NK1R antagonist L-733,060 topically administered twice daily throughout for 14 days....
Adhesive hydrogels based on chemically modified photocrosslinkable polymers with specific physicochemical properties are frequently utilized for sealing wounds or incisions. These adhesive offer tunable characteristics such as tailorable tissue adhesion, mechanical properties, swelling ratios, and enzymatic degradability. In this study, we developed optimized a patch, GelPatch, high burst pressure, minimal swelling, application an ocular (sclera subconjunctival) adhesive. To achieve this,...
We provide a functional characterization of transcription factor NF-κB in protists and information about the evolution diversification this biologically important protein. characterized two using phylogenetic, cellular, biochemical techniques. holozoan Capsaspora owczarzaki (Co) has an N-terminal DNA-binding domain C-terminal Ankyrin repeat (ANK) domain, its specificity is more similar to metazoan proteins than Rel proteins. Removal ANK allows Co-NF-κB enter nucleus, bind DNA, activate...