A5032629653- Invertebrate Immune Response Mechanisms
- CRISPR and Genetic Engineering
- Hip and Femur Fractures
- Protist diversity and phylogeny
- Plant-Microbe Interactions and Immunity
- Mosquito-borne diseases and control
- Viral Infectious Diseases and Gene Expression in Insects
- Metastasis and carcinoma case studies
- Biotin and Related Studies
- Pituitary Gland Disorders and Treatments
- Parasitic Infections and Diagnostics
- Bone health and osteoporosis research
- Cellular transport and secretion
- Echinoderm biology and ecology
- Glioma Diagnosis and Treatment
- Adrenal and Paraganglionic Tumors
- Gastrointestinal Tumor Research and Treatment
- Nutrition and Health in Aging
- Gastric Cancer Management and Outcomes
Boston University
2021-2025
Quinnipiac University
2022-2023
The death and clearance of nurse cells is a consequential milestone in Drosophila melanogaster oogenesis. In preparation for oviposition, the germline-derived bequeath to developing oocyte all their cytoplasmic contents undergo programmed cell death. controlled non-autonomously precipitated by epithelial follicle somatic origin acquiring squamous morphology acidifying externally. Alternatively, stressors such as starvation can induce earlier mid-oogenesis, manifesting apoptosis signatures,...
Abstract The death and clearance of nurse cells is a consequential milestone in Drosophila melanogaster oogenesis. In preparation for oviposition, the germline-derived bequeath to developing oocyte all their cytoplasmic contents undergo programmed cell death. controlled non-autonomously precipitated by epithelial follicle somatic origin acquiring squamous morphology acidifying externally. Alternatively, stressors such as starvation can induce earlier mid-oogenesis, manifesting apoptosis...
We provide a functional characterization of transcription factor NF-κB in protists and information about the evolution diversification this biologically important protein. characterized two using phylogenetic, cellular, biochemical techniques. holozoan Capsaspora owczarzaki (Co) has an N-terminal DNA-binding domain C-terminal Ankyrin repeat (ANK) domain, its specificity is more similar to metazoan proteins than Rel proteins. Removal ANK allows Co-NF-κB enter nucleus, bind DNA, activate...
Abstract Background Distinguishing between a pituitary adenoma and pituicytoma can be challenging. Hormonal changes in pituicytomas are uncommon, the tumor's mass effect has triggered most symptoms. There were only two reported cases of with elevated hormonal levels patients who presented Cushing syndrome as 2017. Case presentation This report describes rare case patient had from pituitary-related hypercortisolism, likely neuroendocrine features benefit early detection surgical resection....
Apoptosis and the engulfment of dead cells are essential processes for proper development maintenance an organism. While apoptosis is well‐characterized, many modulatory signals that control apoptotic cell have not been well described. We use Drosophila ovary as a model death clearance, where follicle act non‐professional phagocytes engulf dying germline. In this system, several transmembrane receptors, such Draper, found to be nurse clearance by cells. However, large‐scale approaches used...
Carcinosarcoma is a rare malignant neoplasm that composed of both epithelial and mesenchymal tumor components. Gastric carcinosarcoma even more often diagnosed at late stage. In this report, we investigate case early gastric with regional lymph node metastasis in 78-year-old woman. The patient underwent partial gastrectomy, lymphadenectomy, splenectomy. was confined to the submucosa, biopsy specimen led histological diagnosis adenocarcinoma, squamous-cell carcinoma, undifferentiated...