A5102027745- Ovarian cancer diagnosis and treatment
- Neuroinflammation and Neurodegeneration Mechanisms
- Endometrial and Cervical Cancer Treatments
- Graphene and Nanomaterials Applications
- Total Knee Arthroplasty Outcomes
- Spinal Cord Injury Research
- Orthopaedic implants and arthroplasty
- Nerve injury and regeneration
- Nanoparticles: synthesis and applications
- COVID-19 Clinical Research Studies
- Hip disorders and treatments
- Intensive Care Unit Cognitive Disorders
- Neurogenesis and neuroplasticity mechanisms
- Bone Tissue Engineering Materials
- Genetic Associations and Epidemiology
- Long-Term Effects of COVID-19
- Uterine Myomas and Treatments
- Knee injuries and reconstruction techniques
- Multiple and Secondary Primary Cancers
- Spondyloarthritis Studies and Treatments
- S100 Proteins and Annexins
- Pelvic floor disorders treatments
- Ferroptosis and cancer prognosis
- Orthopedic Infections and Treatments
- Carbon and Quantum Dots Applications
Xi'an Honghui Hospital
2017-2024
Xi'an Jiaotong University
2014-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Xijing Hospital
2021-2024
Shandong Provincial Hospital
2024
Shandong First Medical University
2024
Peking Union Medical College Hospital
2024
Air Force Medical University
2021
Beijing Obstetrics and Gynecology Hospital
2019-2020
Capital Medical University
2019-2020
Abstract Microglia/macrophages are major contributors to neuroinflammation in the central nervous system (CNS) injury and exhibit either pro- or anti-inflammatory phenotypes response specific microenvironmental signals. Our latest vivo vitro studies demonstrated that curcumin-treated olfactory ensheathing cells (aOECs) can effectively enhance neural survival axonal outgrowth, transplantation of aOECs improves neurological outcome after spinal cord (SCI). The therapeutic effect is largely...
Background. Diabetic retinopathy (DR) is a diabetic microvascular complication and leading cause of vision loss. However, there lack effective strategies to reduce the risk DR currently. The present study aimed at assessing causal effect lipid-regulating targets on using two-sample Mendelian randomization (MR) study. Method. Genetic variants within or near drug target genes, including eight for LDL-C (HMGCR, PCSK9, NPC1L1), HDL-C (CETP, SCARB1, PPARG), TG (PPARA LPL), were selected as...
To describe the clinical and pathological features of endometrial carcinoma with extraperitoneal metastasis examine whether surgery could improve prognosis.The Surveillance, Epidemiology, End Results database was used to analyze 730 patients who were diagnosed cancer from 2010 2015, including lung, bone, or brain.Of patients, 372 (50.96%) had single lung metastases, 196(26.85%) multiple organ metastases that included pulmonary invasion. Therefore, most common target for cancer. In...
Hip ankylosis is a prevalent condition in patients with Ankylosing spondylitis (AS) that can significantly impact their psychological well-being. This study aimed to investigate the of Total Arthroplasty (THA) on anxiety and depression among AS patients.62 undergoing primary THA were recruited separated into two groups based preoperative hip motion. The 40 mobility 0° assigned group A, others NA. Self-rating Anxiety Scale (SAS), Depression scale (SDS), Harris scores (HHS) 36-Item Short Form...
The aim of this study was to clarify the features and prognostic significance isolated para-aortic lymphatic metastasis endometrial cancer.A retrospective patients with stage IIIC cancer performed based on Surveillance, Epidemiology, End Results (SEER) database. A total 2767 were divided into three groups according patterns: pelvic metastasis, dual metastasis. clinic-pathological characteristics prognosis compared among groups.The proportion 13.70%. Patients or shared similar histological...
The present study was to investigate whether the HEART score can be used evaluate cardiovascular risks and reduce unnecessary cardiac imaging in China. Acute coronary syndrome patients with thrombosis myocardial infarction risk < 2 were enrolled emergency department. Baseline data collected a determined each participant during indexed visit. Participants follow-up for 30 days after discharge studied endpoints included acute infarction, mortality all-cause mortality. A total of 244 loss...
Ti6Al4V is a widely used orthopedic implant material in clinics. Due to its poor antibacterial properties, surface modification required prevent peri-implantation infection. However, chemical linkers for have generally been reported detrimental effects on cell growth. In this work, by optimizing parameters related electrodeposition, composite structural coating with graphene oxide (GO) compact films the inner layer and 35 nm diameter strontium (Sr) nanoparticles outer was constructed of...
Abstract Microglia play a central role in maintenance of brain homeostasis. Microglial polarization plays an important the recovery homeostasis after acute ischemic stroke (AIS). DCPIB, as blocker volume-regulated ion channel maintaining intracellular But relationship between DCPIB and microglial M1/M2 is currently unclear. This study to investigate AIS. C57BL/6 mice were subjected transient middle cerebral artery occlusion (tMCAO). was given within 5 min reperfusion. Behavior assessments...
Colpocleisis is one of traditional surgical procedures for elderly and frail women with advanced pelvic organ prolapse. The occurrence de novo urinary incontinence following colpocleisis was considered to impair the postoperative quality life. incidence after has been reported be ranging from 6.6 % 27 %. There an absence prospective large-sample study investigate accurate impact on life till now.
Summary Objective To investigate the genetic level causal association among hyperthyroidism, hypothyroidism, and rheumatoid arthritis (RA). Methods We utilized genome-wide studies (GWAS) summary data for exposure (hyperthyroidism hypothyroidism) outcome (RA) from IEU OpenGWAS database. used two different sets of (test cohort validation cohort) assessment outcome. establish a relationship between these conditions, we conducted two-sample Mendelian randomization (MR) analysis. Subsequently,...
Introduction:This study used single-center data to analyze the clinicopathological features of site-specific endometrial cancer.Methods: Patients with carcinoma who had undergone surgery at Peking Union Medical College Hospital, China, between March 2016 and January 2022 were enrolled.Clinical information pathological characteristics summarized, microsatellite status was analyzed using immunohistochemical method.Patient prognoses measured in terms rates overall survival progression-free...