A5051373891- Diet and metabolism studies
- Diet, Metabolism, and Disease
- Cancer-related molecular mechanisms research
- PI3K/AKT/mTOR signaling in cancer
- Mast cells and histamine
- Metabolomics and Mass Spectrometry Studies
- Genomics, phytochemicals, and oxidative stress
- Adipose Tissue and Metabolism
- Pregnancy and Medication Impact
- Cardiac Ischemia and Reperfusion
- RNA modifications and cancer
- Acute Kidney Injury Research
- Epigenetics and DNA Methylation
- Nutritional Studies and Diet
Lomonosov Moscow State University
2021-2024
The positive effects of female sex hormones, particularly estradiol and progesterone, have been observed in treatment various pathologies. Acute kidney injury (AKI) is a common condition hospitalized patients which the molecular mechanisms hormone action are poorly characterized. In this study, we investigated influence progesterone on renal cells during ischemic injury. We performed both vivo experiments male rats vitro tubular (RTCs) obtained from kidneys intact animals different sexes....
Introduction: The study aimed to investigate the effects of low concentrations mitochondrial uncouplers in endothelial cells on CpG dinucleotide methylation ICAM1 gene promoter. excessive inflammatory response endothelium is responsible for development many cardiovascular diseases. Mitochondria are important regulators cell functions. Mild uncoupling oxidative phosphorylation and respiration mitochondria exerts a long lasting anti-inflammatory effect. However, detailed mechanism activity...