A5054458732- Advanced Radiotherapy Techniques
- Cancer, Hypoxia, and Metabolism
- Medical Imaging Techniques and Applications
- Radiation Therapy and Dosimetry
- Lung Cancer Diagnosis and Treatment
- Effects of Radiation Exposure
- Breast Cancer Treatment Studies
- Head and Neck Cancer Studies
- Esophageal Cancer Research and Treatment
- Lymphoma Diagnosis and Treatment
- DNA Repair Mechanisms
- Brain Metastases and Treatment
- Glioma Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Hepatocellular Carcinoma Treatment and Prognosis
- Pancreatic and Hepatic Oncology Research
- Radiation Dose and Imaging
- Gastric Cancer Management and Outcomes
- Carcinogens and Genotoxicity Assessment
- Management of metastatic bone disease
- Nanoplatforms for cancer theranostics
- Radiomics and Machine Learning in Medical Imaging
- Prostate Cancer Diagnosis and Treatment
- Sarcoma Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
Juntendo University
2015-2024
Kansai Electric Power Hospital
2024
Satou Hospital
2022
Juntendo University Hospital
2011-2020
University hospital Medical Information Network
2020
Chinese Academy of Medical Sciences & Peking Union Medical College
2017
Hosei University
2016
Jōetsu General Hospital
2012
Tokyo Metropolitan Komagome Hospital
2011
Niigata University
1969-2010
We investigated the relationship between white-matter alteration and cognitive status in Parkinson's disease (PD) with without dementia by using diffusion tensor imaging.Twenty PD patients, 20 PDD (Parkinson's dementia) patients age-matched healthy controls underwent imaging. The mean diffusivity fractional anisotropy (FA) map of each patient group were compared those control tract-based spatial statistics. Tractography images genu corpus callosum fibre tracts generated, FA measured.FA...
Abstract Purpose: To determine whether quantitative arterial spin labeling (ASL) can be used to evaluate regional cerebral blood flow in Parkinson's disease with dementia (PDD) and without (PD). Materials Methods: Thirty‐five PD patients, 11 PDD 35 normal controls were scanned by using a ASL method 3 Tesla MRI unit. Regional was compared the posterior cortex region‐of‐interest analysis. Results: patients showed lower than ( P = 0.002 0.001, respectively, analysis of variance Bonferroni post...
Poly( ADP ‐ribose) polymerase ( PARP )‐1 promotes base excision repair and DNA strand break repair. Inhibitors of enhance the cytotoxic effects γ‐irradiation X ‐irradiation. We investigated impact inhibition on responses to (low liner energy transfer [ LET ] radiation) carbon‐ion irradiation (high in human pancreatic cancer cell line MIA P a C a‐2. Cell survival was assessed by colony formation assay after combination treatment with inhibitor AZD 2281 single fraction (13 70 keV/μm 13 70])....
PURPOSE: To prospectively investigate whether intracranial germinomas, except large ones, can be cured with radiation doses lower than 50 Gy and to determine 10-year follow-up results. MATERIALS AND METHODS: Between 1985 1995, 38 patients germinoma diagnosed histologically or established criteria were enrolled. Total the primary tumor site 36 after total removal, 40 for tumors less 2.5 cm in diameter, 45 those 2.5–4.0 cm, greater 4.0 1.6–1.8-Gy daily fractions. Patients underwent irradiation...
To determine the patterns of gene expression responsible for radiosensitivity glioblastoma cells, we analyzed transcriptional changes after ionizing radiation in different cell lines. After completing clonogenic survival assays, selected two lines with radiosensitivities. Subsequently, they were investigated by using technique DNA microarray, and then categorized upregulated genes into 10 groups. Between lines, difference percentage repair/replication category was largest, this present at a...
The effects of high-dose irradiation on the morphology haversian bone were studied, over a fifty-two-week period, in seventy-seven adult rabbits, after administration single dose radiation (therapeutic x-ray; twenty-five, fifty, or 100 gray) to one knee joint. specimens examined with microangiography, light and transmission electron microscopy, histomorphometry. Analysis was performed subchondral plate weight-bearing portions femoral condyles. Microangiography demonstrated dilatation...
The radiation response of SCCVII tumor cells in C3H/He mice under various irradiation conditions was studied using an vivo-in vitro assay. When tumor-bearing were irradiated without anesthesia or physical restraint, the had a hypoxic fraction 5.4%. Both and immobilization leg with adhesive tape produced significant increases (23 28%, respectively). Restraining mouse jig immobilizing also increased (13%).
This study investigates the relationship between clinical features of lymphoma in ocular adnexal region and revised European American (REAL) classification. Specimens from 41 patients with lymphoproliferative disease were reassessed pathologically using REAL Thirty-two primary non-Hodgkin's lymphomas (NHL) included study, almost all them having been treated radiotherapy or without chemotherapy. Seven 32 NHL showed distant recurrence after treatment: 3 out 26 extranodal marginal zone B-cell...