A5038204118- Anesthesia and Pain Management
- Pain Management and Opioid Use
- Epilepsy research and treatment
- Anesthesia and Sedative Agents
- Pediatric Pain Management Techniques
- Total Knee Arthroplasty Outcomes
- Pharmacovigilance and Adverse Drug Reactions
- Antibiotics Pharmacokinetics and Efficacy
- Schizophrenia research and treatment
- Opioid Use Disorder Treatment
- Dental Anxiety and Anesthesia Techniques
- Orthopaedic implants and arthroplasty
- Nausea and vomiting management
- Pharmacological Effects and Toxicity Studies
Frederiksberg Hospital
2024-2025
Copenhagen University Hospital
2024-2025
Næstved Sygehus
2018-2022
Zealand University Hospital
2022
Zealand University Hospital Køge
2018-2019
<h3>Importance</h3> Multimodal postoperative analgesia is widely used but lacks evidence of benefit. <h3>Objective</h3> Investigate beneficial and harmful effects 4 nonopioid analgesics regimens. <h3>Design, Setting, Participants</h3> Randomized, blinded, placebo-controlled, 4-group trial in 6 Danish hospitals with 90-day follow-up that included 556 patients undergoing total hip arthroplasty (THA) from December 2015 to October 2017. Final date was January 1, 2018. <h3>Interventions</h3>...
Abstract Objective The aim of the study is to provide insight into real‐world use therapeutic drug monitoring ( TDM ) for most common antiseizure medications ASMs ). Methods In total, 137 586 samples from period 2019–2023 were collected five main Danish laboratories performing TDM. A previously described algorithm developed exclude abnormal results patient data was applied. This resulted in inclusion 84 951 53 406 patients. Concentration ranges calculated as 10th 90th percentiles datasets...
We report a poisoning with paliperidone palmitate, once‐monthly, long‐acting injectable antipsychotic. The patient suffered from deep sedation and dystonia. She had been treated extended release intramuscular for several years received her last injection 8 days prior to admission. plasma was nearly five times higher than the upper reference range. Paliperidone is substrate of p‐glycoprotein we therefore aimed increase its elimination by inducing through treatment St John's wort. This seemed...
Nerve block of the lateral femoral cutaneous nerve (LFCN) is a predominantly sensory block. It reduces pain following total hip arthroplasty (THA), but non-responder rate high. We hypothesized, that an increased volume ropivacaine, would result in greater coverage incisions used for THA. conducted randomized, blinded trial 20 healthy volunteers. Participants were randomized to receive bilateral LFCN-blocks with 8 mL ropivacaine 0.75% on left side and 16 right side, or vice versa. Allocation...
Background The lateral femoral cutaneous nerve ( LFCN ) block may be used for post‐operative pain management in patients undergoing total hip arthroplasty. aim of this trial was to investigate the sensory coverage posterior and incision lines involvement after an block. Methods study a randomised, blinded 20 healthy volunteers. All subjects received bilateral randomised 8 ml ropivacaine on right side isotonic saline left side, or vice versa. An orthopaedic surgeon depicted (invisible...
Evidence suggests that available antiemetics are equal to intravenous fluid treatment against acute nausea of other causes than motion sickness, pregnancy, anaesthesia, chemo- or radiation therapy. Each antiemetic is associated with adverse effects, which include movement disorders, sedation, and QT prolongation. Intravenous directed underlying pathology recommended as a first-line in these patients. If an clinically warranted, ondansetron has the most favourable ratio between side effects...