A5085701863- Glioma Diagnosis and Treatment
- Ferroptosis and cancer prognosis
- Radiopharmaceutical Chemistry and Applications
- Transcranial Magnetic Stimulation Studies
- Neural dynamics and brain function
- Functional Brain Connectivity Studies
- Advanced Chemical Sensor Technologies
- RNA modifications and cancer
- Nanoplatforms for cancer theranostics
- Neural and Behavioral Psychology Studies
- Glycosylation and Glycoproteins Research
- Neurological disorders and treatments
- Vestibular and auditory disorders
- Nanoparticle-Based Drug Delivery
- Barrier Structure and Function Studies
- Supramolecular Self-Assembly in Materials
- Chemical Synthesis and Analysis
- Olfactory and Sensory Function Studies
- Color perception and design
- Pain Management and Treatment
- Tactile and Sensory Interactions
- Brain Metastases and Treatment
- Neuroscience and Neural Engineering
- Peptidase Inhibition and Analysis
- EEG and Brain-Computer Interfaces
Stanford University
2021-2025
Neurosciences Institute
2021-2025
Stanford Medicine
2021-2023
VA Palo Alto Health Care System
2022
Mental Illness Research, Education and Clinical Centers
2022
University of Oxford
2022
University of Southern California
2017
The sensory experience of transcranial magnetic stimulation (TMS) evokes cortical responses measured in electroencephalography (EEG) that confound interpretation TMS-evoked potentials (TEPs). Methods for masking have been proposed to minimize contributions the TEP, but most effective combination suprathreshold TMS dorsolateral prefrontal cortex (dlPFC) is unknown. We applied suppression techniques and quantified electrophysiology perception from dlPFC identify best TEP. In 21 healthy adults,...
Abstract Purpose: Despite optimal local therapy, tumor cell invasion into normal brain parenchyma frequently results in recurrence patients with solid tumors. The aim of this study was to determine whether microvascular inflammation can be targeted better delineate the tumor-brain interface through vascular adhesion molecule-1 (VCAM-1)-targeted MRI. Experimental Design: Intracerebral xenograft rat models MDA231Br-GFP (breast cancer) metastasis and U87MG (glioblastoma) were used...
ABSTRACT Objective To characterize early TEPs anatomically and temporally (20-50 ms) close to the TMS pulse (EL-TEPs), as well associated muscle artifacts (<20 ms), across dlPFC. We hypothesized that location angle influence EL-TEPs, EL-TEP amplitude is inversely related artifact. Additionally, we sought determine an optimal group-level target angle, while investigating potential benefits of a personalized approach. Methods In 16 healthy participants, applied single-pulse six targets...
How does a train of TMS pulses modify neural activity in humans? Despite adoption repetitive (rTMS) for the treatment neuropsychiatric disorders, we still do not understand how rTMS changes human brain. This limited understanding stems part from lack methods noninvasively measuring effects single train-a fundamental building block treatment-as well as cumulative consecutive trains. Gaining this would provide foundational knowledge to guide next generation treatments. Here, overcome...
ABSTRACT Objective We currently lack a robust noninvasive method to measure prefrontal excitability in humans. Concurrent TMS and EEG the cortex is usually confounded by artifacts. Here we asked if real-time optimization could reduce artifacts enhance TMS-EEG of left excitability. Methods This closed-loop procedure adjusts dlPFC coil location, angle, intensity based on response TMS. Our outcome was early (20-60 ms) local TMS-evoked potential (EL-TEP). Results In 18 healthy participants, this...
Atherosclerosis is a major contributor to cardiovascular disease, the leading cause of death worldwide, which claims 17.3 million lives annually. also sudden and myocardial infarction, instigated by unstable plaques that rupture occlude blood vessel without warning. Current imaging modalities cannot differentiate between stable rupture. Peptide amphiphiles micelles (PAMs) can overcome this drawback as they be modified with variety targeting moieties bind specifically diseased tissue....
How does a train of TMS pulses modify neural activity in humans? Despite adoption repetitive (rTMS) for the treatment neuropsychiatric disorders, we still do not understand how rTMS changes human brain. This limited understanding stems part from lack methods noninvasively measuring effects single - fundamental building block as well cumulative consecutive trains. Gaining this would provide foundational knowledge to guide next generation treatments. Here, overcome limitation, developed...
Atherosclerosis is a major contributor to cardiovascular disease, the leading cause of death worldwide, which claims 17.3 million lives annually. also sudden and myocardial infarction, instigated by unstable plaques that rupture occlude blood vessel without warning. Current imaging modalities cannot differentiate between stable rupture. Peptide amphiphiles micelles (PAMs) can overcome this drawback as they be modified with variety targeting moieties bind specifically diseased tissue....
Abstract Background The sensory experience of transcranial magnetic stimulation (TMS) evokes cortical responses measured in EEG that confound interpretation TMS-evoked potentials (TEPs). Methods for masking have been proposed to minimize contributions the TEP, but most effective combination suprathreshold TMS dorsolateral prefrontal cortex (dlPFC) is unknown. Objective We applied suppression techniques and quantified electrophysiology perception from dlPFC identify best TEP. In 21 healthy...
Supplementary Figure from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface
Supplementary Figure from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface
Supplementary Figure from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface
Supplementary Figure from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface
Supplementary Figure from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface
Supplementary Data from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface
Supplementary Figure from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface
Supplementary Figure from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface
Supplementary Figure from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface