A5016943104- Stress Responses and Cortisol
- Hormonal Regulation and Hypertension
- Diabetes Treatment and Management
- Phytochemistry and Biological Activities
- Immune Response and Inflammation
- Regulation of Appetite and Obesity
- Apelin-related biomedical research
- Spaceflight effects on biology
- Inflammatory Biomarkers in Disease Prognosis
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Pharmaceutical Economics and Policy
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Hormonal and reproductive studies
- Anesthesia and Neurotoxicity Research
- Vitamin K Research Studies
- Pharmacological Effects of Natural Compounds
- Adipokines, Inflammation, and Metabolic Diseases
- Alcoholism and Thiamine Deficiency
- Coronary Artery Anomalies
- Pharmaceutical Quality and Counterfeiting
- Drug-Induced Hepatotoxicity and Protection
- Vascular anomalies and interventions
- Intellectual Property and Patents
- Medicinal plant effects and applications
- Congenital Heart Disease Studies
Fundação Oswaldo Cruz
2020-2024
Maine Medical Center
2022
Universidade Federal do Estado do Rio de Janeiro
2016
Universidade Federal do Rio de Janeiro
2016
Sepsis is one of the most common comorbidities observed in diabetic patients, associated with a deficient innate immune response. Recently, we have shown that glucagon possesses anti-inflammatory properties. In this study, investigated if hyperglucagonemia triggered by diabetes might reduce migration neutrophils, increasing sepsis susceptibility. 21 days after induction intravenous injection alloxan, induced moderate Swiss-Webster mice through cecum ligation and puncture (CLP). The receptor...
Evidence demonstrates the bidirectional communication and regulation between neuroendocrine immune systems. Thyroid hormones play key roles in nervous system development can exert influence on various cells contributing to pathophysiological conditions. Octyl methoxycinnamate (OMC) is one of most commonly used UV filters, vitro vivo studies have found thyroid disrupting effects. The present study assessed whether OMC administration mice dams during lactational period cause disruption...
Prior investigation shows an increase in the activity of both hypothalamus-pituitary-adrenal (HPA) axis and renin-angiotensin system (RAS) diabetic patients. Moreover, activation angiotensin-II type 1 receptor (AT1) has been associated with adrenal steroidogenesis. This study investigates role RAS on overproduction corticosterone mice. Diabetes was induced by intravenous injection alloxan into fasted Swiss-webster Captopril (angiotensin-converting enzyme inhibitor), Olmesartan (AT1...
Prior research demonstrated that glucagon has protective roles against inflammation, but its effect on the resolution of inflammation remains elusive. Using in vitro and vivo approaches, this study aimed to investigate pro-resolving potential pulmonary neutrophilic caused by lipopolysaccharide. Lipopolysaccharide induced an increase proportions neutrophils positives receptor (GcgR) . In addition, lipopolysaccharide neutrophil accumulation expression GcgR inflammatory cells lungs, however,...
Solidago chilensis Meyen (Compositae) is a species native to South America (Brazil) popularly known as arnica. In Brazilian popular medicine, inflorescences and rhizomes of this plant have been used since the end 19th century replace exogenous hepatotoxic Arnica montana L. in treatment edema inflammatory pathologies. Although anti-inflammatory activity S. evidenced literature, there lack studies with enriched fractions or compounds isolated from it. The objective current study was...
A number of risk factors have been associated to the stroke and many strategies proposed in order control them as well. Vitamin K has largely found brain, which suggests a possible function at that tissue. This study aimed evaluate potential this vitamin on prevention cognitive SHRSP rats. Twelve males, 15 weeks old, were divided into two groups (n= 6 each), receiving vehicle-coconut oil (control group) or 40 μg phylloquinone (treated during 28 days. Biological parameters, systolic blood...