A5051317536- Synthesis and Catalytic Reactions
- Organic Chemistry Cycloaddition Reactions
- Oxidative Organic Chemistry Reactions
- Synthesis of β-Lactam Compounds
- Essential Oils and Antimicrobial Activity
- Synthesis and Biological Evaluation
- Crystallization and Solubility Studies
- Chemical Synthesis and Reactions
- X-ray Diffraction in Crystallography
- Phytochemicals and Antioxidant Activities
- Catalytic Cross-Coupling Reactions
- Synthesis and Reactions of Organic Compounds
- Crystallography and molecular interactions
- Fluorine in Organic Chemistry
- Catalytic C–H Functionalization Methods
- Asymmetric Synthesis and Catalysis
- Crystal structures of chemical compounds
- Click Chemistry and Applications
- Sulfur-Based Synthesis Techniques
- Synthesis of heterocyclic compounds
- Ziziphus Jujuba Studies and Applications
- Synthesis and Biological Activity
- Allelopathy and phytotoxic interactions
- Advanced Glycation End Products research
- Chemical Reactions and Isotopes
University of Sfax
2012-2024
Institut Supérieur de Biotechnologie de Sfax
2019
Centre of Biotechnology of Sfax
2015-2016
Institut National Agronomique de Tunisie
2000-2007
Centre National de la Recherche Scientifique
2002-2003
Institut de Chimie des Substances Naturelles
2002-2003
AbstractAbstractThis study was designed to examine chemical composition and antioxidant activity as well the in vitro α-amylase pancreatic lipase angiotensin-converting enzyme inhibitory activities of essential oil various extracts Eucalyptus globules leaves collected from Sfax (Tunisia). The main constituents (≥ 7%) identified by GC-MS E. globulus are 1,8-cineole (48.2%), α-pinene (16.1%), γ-terpinene (8.9%) p-cymene (8.8%). IC50 values oil, hexane, ethyl acetate methanolic against were...
The chemical composition, the antioxidant activity as well antibacterial of essential oil and various extracts Ephedra alata alenda grows in Tunisia were evaluated. GC-MS analysis resulted identifying 19 compounds representing 93.9 % oil, linalool (19.3 %), (Z)-3-tridecene (7.8 n-pentadecane (7.6 1,8-cineole (7.1 major compounds. (IC50 = 0.027 mg /ml) methanolic extract highest comparison with other extracts.
Abstract The N-alkyl oxaziridines may be used as reagents for the oxidation of sulfides in acid-promoted reactions. present work describes behavior two newly synthesized dihydroisoquinoline-derived with respect to methanesulfonic acid. An isomerization reaction was observed absence sulfide.
Oleuropein is the major phenolic compound extracted from olive leaves and it also present in fruits virgin oil. It has already demonstrated a wide range of pharmacological activities, but new derivatives have to be designed order obtain useful Structure–Activity Relationships for this family products, as well analogs with improved and/or different biological properties. However, taking into account multiple OH groups (catechol sugar) oleuropein, selective modification natural product...
N-Alkyl oxaziridines may be used as reagents for the oxidation of sulfides in acid-promoted reactions. This article reports on a simple and efficient synthesis two new trichloromethyl substituted dihydroisoquinoline oxaziridines, family organic oxidizing agents. Their oxygen transfer capability with respect to model substrates absence acid is investigated.
Abstract Treatment of N‐methylcarbonyl 1, N‐phenylthioamido 2, and N‐cyano 3 iminoethers with perfluoroalkylated hydrazines leads to 1‐perfluoroalkyl‐5‐methyl‐1,2,4‐ triazoles, 4,1‐perfluoroalkyl‐5‐phenylamino‐1,2,4‐triazoles 5, 1‐perfluoroalkyl‐5‐amino‐1,2,4‐triazoles 6 in good yields. These compounds are screened for their biological activities.
Abstract N-Alkyl-oxaziridines react in the presence of a nucleophile as an oxygenating agent; absence nucleophile, isomerization reaction is observed. This study describes synthesis two new dihydroisoquinoline oxaziridines and their reactivity acid-promoted sulfides.
Palladium-catalyzed oxidative C-H halogenation and acetoxylation reactions of S-unprotected sulfides, selectively directed by pyridinyl groups, allows the formation C-X bonds (X = I, Br, Cl, OAc) using simple halosuccinimide or phenyliodine diacetate (PIDA) oxidants. The undesired sulfoxides and/or sulfones, which are usually observed under conditions, is fully obviated. Under solvent-dependent conditions that we proposed, sulfide functionalization achieved in less than 1 h without any...
This paper describes the synthesis of a series dihydroisoquinoline nitrones by isomerization corresponding oxaziridines. Nitrones 4a–c were obtained in excellent yields and high purity simple effective method from The synthesized compounds also evaluated for their antibacterial activity against Gram-positive Gram-negative bacteria fungus.
N-Alkyl oxaziridines react as oxygenating reagents in the presence of a nucleophile.In this work, we describe synthesis new dihydroisoquinoline oxaziridines, and their reactivity an acid-promoted reaction both absence sulfides.In sulfides, nitrone is produced.
We report here the synthesis and X-ray crystallography of dihydroisoquinoline oxaziridines with methyl substitute in position 1 nitro group 7 (compound 3b). also synthesized compound 3a without nitro. These compounds have been prepared by peracidic oxidation imines m-chloroperbenzoic (m-CPBA) like oxidizing agent. This two exhibit higher antifungal activity.
Abstract The reaction of 3,3-dimethyl-7-nitro-3,4-dihydroisoquinoline 1 with m-chloroperbenzoic acid (m-CPBA) mainly yielded oxaziridine and nitrone, their selectivities being dependent on the solvents. 2.5 equivalents m-CPBA gave small amounts oxaziridines hydroxamic acids as well isolated O-acylhydroxamate compounds.
The heck reaction of aryl bromide with styrene in N,N-dimethyl formamide/water as solvent has been studied using different catalysts under ultrasonic irradiation at room temperature. effect the solvent, base, and catalyst transfer phase were studied. results show that increases yield becomes faster amount aliquat-336.