A5073666310- Pharmacovigilance and Adverse Drug Reactions
- HIV/AIDS drug development and treatment
- Drug-Induced Adverse Reactions
- Pharmaceutical industry and healthcare
- Schizophrenia research and treatment
- Biochemical and Molecular Research
- HIV Research and Treatment
- Pharmaceutical Economics and Policy
- Treatment of Major Depression
- Bacterial Infections and Vaccines
- Health Systems, Economic Evaluations, Quality of Life
- Vaccine Coverage and Hesitancy
- Hepatitis C virus research
- Antimicrobial Resistance in Staphylococcus
- Adenosine and Purinergic Signaling
- Gastroesophageal reflux and treatments
- Functional Brain Connectivity Studies
- Peripheral Neuropathies and Disorders
- Suicide and Self-Harm Studies
- Academic integrity and plagiarism
- Sarcoidosis and Beryllium Toxicity Research
- Infectious Diseases and Tuberculosis
- Sympathectomy and Hyperhidrosis Treatments
- Helicobacter pylori-related gastroenterology studies
- Neurotransmitter Receptor Influence on Behavior
Institut de Neurosciences des Systèmes
2018-2022
Inserm
2016-2022
Assistance Publique Hôpitaux de Marseille
2015-2019
Hôpital de la Timone
2018
Institut de Neurosciences de la Timone
2016-2017
Centre National de la Recherche Scientifique
2016-2017
Aix-Marseille Université
2016-2017
Délégation Régionale Provence-Alpes-Côte d’Azur et Corse
2017
Pharmac
2017
Centre de Recherche en Cancérologie de Lyon
2016
The study aim was to assess the abuse/misuse potential of second-generation antipsychotics (SGAPs) using VigiBase data. We extracted individual case safety reports "Drug abuse, dependence and withdrawal" involving SGAPs up June 2018. assessed disproportionate reporting by calculating information component, considering lower end 95% credibility interval for component (IC025 ), proportional ratio. identified 1683 recorded as "abuse, SGAPs, mainly quetiapine (n = 1089) olanzapine 209)....
Introduction : La notification spontanée des effets indésirables médicamenteux (EIMs) est un piliers de la surveillance en post-AMM. Une principales limites cette dernière concerne qualité l’information ces notifications. L’objectif principal étude était d’évaluer l’informativité observations d’EIMs enregistrées dans Base Nationale PharmacoVigilance (BNPV) à partir déclarations médecins généralistes (MGs). secondaire d’identifier les facteurs associés une déclaration complète. Méthode Toutes...
Objectives: Ribavirin (RBV) induced anemia may be influenced by host genetic factors affecting RBV transport solute carrier (SLC) or metabolism inosine triphosphatase (ITPA), as already reported. We investigated the influence of single nucleotide polymorphisms (SNPs) on SLC genes anemia, trough concentration (Ctrough) and response in HIV–hepatitis C virus coinfected patients receiving triple therapy with boceprevir telaprevir. Methods: Patients from ANRS HC26/HC27 studies were genotyped for...
Background We aimed to determine the impact of inosine triphosphatase (ITPA) deficiency on ribavirin (RBV)-induced anaemia in HIV–HCV-coinfected patients receiving a triple therapy including haematotoxic direct-acting antiviral agent boceprevir (BOC). Methods Patients ANRS HC27 BocepreVIH study were genotyped for two ITPA single nucleotide polymorphisms involved deficiency. RBV trough concentration (C ) was determined at week (W)4 and W8. Impact anaemia, C , response haematotoxicity (grade...