A5020649562- Advanced biosensing and bioanalysis techniques
- RNA Interference and Gene Delivery
- Protease and Inhibitor Mechanisms
- Immune responses and vaccinations
- Zoonotic diseases and public health
- Antimicrobial Peptides and Activities
- Signaling Pathways in Disease
- DNA and Nucleic Acid Chemistry
- Supramolecular Self-Assembly in Materials
- Advanced Proteomics Techniques and Applications
- Blood Coagulation and Thrombosis Mechanisms
- Biosensors and Analytical Detection
- Quantum Dots Synthesis And Properties
State Key Laboratory of Chemobiosensing and Chemometrics
2020-2022
Hunan University
2020-2022
Suzhou Municipal Hospital
2018-2020
Nanjing Medical University
2018
G-quadruplex (G4) is a noncanonical nucleic acid secondary structure that has implications for various physiological and pathological processes thus essential to exploring new approaches G4 detection in live cells. However, the deficiency of molecular imaging tools makes it challenging visualize ex vivo tissue samples. In this study, we established probe design strategy presented red fluorescent benzothiazole derivative, ThT-NA, detect image structures living cells By enhancing...
DESMIN is a novel prognostic predictor and therapeutic target for colorectal cancer (CRC). Enzyme-linked immunosorbent assay (ELISA) electrochemiluminescence (ELC) assays are large-scale highcost projects; therefore, it necessary to develop new, fast, simple yet highly sensitive specific method detect in serum. Semiconducting quantum dots (QDs) possess high fluorescence yield, stability against photobleaching, size-controlled luminescence properties, thus being utilized photoelectrochemical...
Lipid transferase-catalyzed protein lipidation plays critical roles in many physiological processes and it has been an increasingly attractive therapeutic target from cancer to neurodegeneration, while sensitive detection of lipid transferase activity biological samples remains challenging. Here, we presented AuNP-based colorimetric method with dual-product synergistically enhanced sensitivity for convenient activity. Homo sapiens N-myristoyltransferase 1 (HsNMT1), a key transferase, was...
Enzyme-activated membrane insertion peptide probes were developed for selectively lighting up target cells.
The demographic features, epidemiology, diagnosis and treatment of two cases with falciparum malaria imported into Suzhou City in 2019 were reported. These findings indicate a risk visitors besides high prevalence migrant labors, much attention should be paid to children that are at infections.［摘要］ 对苏州市 年报告的 2 例输入性恶性疟病例的基本信息、流行病学史以及诊治过程资料进行收集、整理和分析。结果 显示, 苏州市输入性疟疾不仅在劳务输出人群中高发, 在探亲访友人群中也存在感染风险, 尤其是儿童感染风险应引起重视。.