Léo Nava Piorsky Dominici Cruz

ORCID: 0000-0003-0010-6692
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About
Contact & Profiles
Research Areas
  • Research on Leishmaniasis Studies
  • Trypanosoma species research and implications
  • Insect and Pesticide Research
  • Genetics, Aging, and Longevity in Model Organisms
  • Circadian rhythm and melatonin
  • Neurobiology and Insect Physiology Research
  • Insect symbiosis and bacterial influences
  • Insect Pest Control Strategies

Fundação Oswaldo Cruz
2021-2023

Universidade Federal do Maranhão
2021

Leishmaniasis is a serious public health concern in the Northeastern region of Brazil, where sand fly fauna well studied, although few species have been identified as competent vectors. The detection Leishmania spp. parasites wild-caught flies could help sanitary authorities draw strategies to avoid transmission and, therefore, incidence leishmaniases. We detected DNA and correlated that data with aspects ecology Caxias municipality, Maranhao State, Brazil. were sampled peridomicile (open...

10.1590/s1678-9946202264032 article EN cc-by-nc Revista do Instituto de Medicina Tropical de São Paulo 2022-01-01

Lutzomyia longipalpis is the natural vector of Leishmania (Leishmania) infantum, but it also permissive for several species that are related to cutaneous leishmaniasis (CL). Maranhao State (Northeast Brazil) endemic CL and has highest number cases diffuse (DCL) in country. It a rare disease associated with defective immune response mainly caused by L. (L.) amazonensis. Additionally, immunosuppressed patients infected etiologic agents increased, including regions which main vectors rare....

10.1590/s1678-9946202163081 article EN cc-by-nc Revista do Instituto de Medicina Tropical de São Paulo 2021-01-01

Abstract Wolbachia pipientis (Hertig) is an endosymbiotic microorganism widespread among arthropods and other invertebrate hosts, employed in strategies to reduce the incidence of arthropod-borne diseases. Here, we used a PCR-based approach for 16S RNA wsp genes investigate prevalence, geographical distribution, strains sand flies (Diptera: Psychodidae: Phlebotominae), main vectors causative agents leishmaniasis, from three biomes Brazil: Amazon, Cerrado, Caatinga. We found that: 1) DNA...

10.1093/jme/tjab130 article EN Journal of Medical Entomology 2021-08-27

Circadian oscillators (i.e., circadian clocks) are essential to producing the rhythms observed in virtually all multicellular organisms. In arthropods, many rhythmic behaviors generated by oscillations of central pacemaker, specific groups neurons protocerebrum which oscillator molecular machinery is expressed and works; however, located other tissues peripheral could also contribute certain rhythms, but not well known non-model Here, we investigated whether eight clock genes that likely...

10.1371/journal.pone.0287237 article EN cc-by PLoS ONE 2023-10-19

Abstract Studies on experimental sand fly infection require the availability of colonies and laboratory conditions. In Brazil, Lutzomyia longipalpis (Diptera: Psychodidae) (Lutz Neiva 1912) is responsible for highest rates by Leishmania spp. this species one most suitable colonization. study, we describe a method growing Lu. in conditions (10 generations) from natural populations sampled region high endemicity visceral leishmaniasis state Maranhão, Northeastern Brazil. Using two methods...

10.1093/jme/tjab053 article EN Journal of Medical Entomology 2021-04-02
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