A5003464752- Research on Leishmaniasis Studies
- Neurobiology and Insect Physiology Research
- Genetics, Aging, and Longevity in Model Organisms
- Mosquito-borne diseases and control
- Trypanosoma species research and implications
- Circadian rhythm and melatonin
- Dengue and Mosquito Control Research
- Insect and Arachnid Ecology and Behavior
- Leptospirosis research and findings
- Insect symbiosis and bacterial influences
- Brucella: diagnosis, epidemiology, treatment
- Malaria Research and Control
- Vector-borne infectious diseases
Fundação Oswaldo Cruz
2018-2023
Instituto de Biologia do Exército
2018
Phlebotomine sand flies are of global significance as important vectors human disease, transmitting bacterial, viral, and protozoan pathogens, including the kinetoplastid parasites genus Leishmania , causative agents devastating diseases collectively termed leishmaniasis. More than 40 pathogenic species transmitted to humans by approximately 35 fly in 98 countries with hundreds millions people at risk around world. No approved efficacious vaccine exists for leishmaniasis available...
Zika has emerged as a new public health threat after the explosive epidemic in Brazil 2015. It is an arbovirus transmitted mainly by Aedes aegypti mosquitoes. The knowledge of physiological, behavioural and biological features virus-infected vectors may help understanding transmission dynamics elucidate their influence vector capacity. We aimed to investigate effects virus (ZIKV) infection behaviour Ae. females analysing locomotor activity, egg production viability. were orally infected with...
Most organisms feature an endogenous circadian clock capable of synchronization with their environment. The most well-known synchronizing agents are light and temperature. mosquitoes, vectors many pathogens, drives important behaviors related to vectoral capacity, including oviposition, host seeking, hematophagy. Main gene expression, as well locomotor activity patterns, has been identified in Aedes aegypti Culex quinquefasciatus under artificial light-dark cycles. Given that these mosquito...
In canine leishmaniosis caused by the protozoan Leishmania infantum, little is known about how co-infections with or co-seropositivities for other pathogens can influence aggravation of this disease. Therefore, objectives study were to evaluate frequency certain in dogs seropositive L. infantum and their relationship clinical signs, histological changes load. Sixty-six infantum-seropositive submitted examination, collection blood bone marrow, culling, necropsy. Antibodies against Anaplasma...
Mosquitoes exhibit activity rhythms, crucial for the transmission of pathogens, under control a circadian clock. Aedes aegypti is one world’s leading vectors. For decades, several studies have linked rise in ambient temperature with increase their activity. Here, we identify candidate genes whose expression influenced by cycles and may affect locomotor We observed that timeless completely lost its rhythmic light/dark, out-of-phase cycles, RNAi mediated knockdown nocte , an important gene...
Circadian oscillators (i.e., circadian clocks) are essential to producing the rhythms observed in virtually all multicellular organisms. In arthropods, many rhythmic behaviors generated by oscillations of central pacemaker, specific groups neurons protocerebrum which oscillator molecular machinery is expressed and works; however, located other tissues peripheral could also contribute certain rhythms, but not well known non-model Here, we investigated whether eight clock genes that likely...
The circadian clock of mosquitoes can influence physiological and behavioral processes linked to disease transmission. Currently, we know how genes are expressed in the head Aedes aegypti different light temperature regimens, but still do not anything about expression these body. present work aims contribute this understanding. We observed that body be from head. Additionally, found cycles have greater on than light/dark cycles.
In canine visceral leishmaniasis, coinfections can aggravate the disease. Our aim was to investigate Brucella canis in dogs infected with Leishmania infantum. One hundred and six L. infantum-seropositive were submitted serology for B. canis, PCR infantum, histopathological analysis of genital tract. Anti-B. antibodies detected seven whose clinical signs, infantum load histological alterations similar those seronegative animals. The circulation anti-B. low but demonstrates exposure this...
Abstract Phlebotomine sand flies are of global significance as important vectors human disease, transmitting bacterial, viral, and protozoan pathogens, including the devastating kinetoplastid parasites genus Leishmania , causative agents diseases collectively termed leishmaniasis. More than 40 pathogenic species transmitted to humans by approximately 35 fly in 98 countries with hundreds millions people at risk around world. As no approved efficacious vaccine exists, available drugs expensive...