A5015112810- MRI in cancer diagnosis
- Intramuscular injections and effects
- Migraine and Headache Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Radiomics and Machine Learning in Medical Imaging
- Dysphagia Assessment and Management
- Tracheal and airway disorders
- Advanced Radiotherapy Techniques
- Botulinum Toxin and Related Neurological Disorders
- Gastrointestinal Tumor Research and Treatment
- Nosocomial Infections in ICU
- Antioxidant Activity and Oxidative Stress
- Healthcare Decision-Making and Restraints
- Surgical Sutures and Adhesives
- Thermoregulation and physiological responses
- Dupuytren's Contracture and Treatments
- Congenital Anomalies and Fetal Surgery
- Renal cell carcinoma treatment
- Immune cells in cancer
- Trace Elements in Health
- Vitamin C and Antioxidants Research
- Heparin-Induced Thrombocytopenia and Thrombosis
- Diabetes Management and Research
- Thyroid and Parathyroid Surgery
- Management of metastatic bone disease
Humboldt-Universität zu Berlin
2021-2025
Charité - Universitätsmedizin Berlin
2020-2025
Freie Universität Berlin
1989-2025
Max Delbrück Center
2024-2025
Bundeswehrkrankenhaus
2015
Orthopädische Universitätsklinik
2003
Pediatric Nephrology of Alabama
2000
Stable metal isotopes have received increasing attention as medical biomarkers due to their potential detect changes in metabolism related diseases. In particular, copper stable are a powerful tool identify isotopic variation between tumors and healthy tissue, suggesting application cancer diagnosis. However, mechanisms causing isotope fractionation, such redox- or bond-forming reactions interactions of metals during transmembrane import export, less well understood. Here, we established an...
Background/Objectives: The aim of this study was to investigate the prognostic value established response assessment tools for hepatocellular carcinoma (HCC) treated with high-dose-rate interstitial brachytherapy (iBT) alone or transarterial chemoembolization (cTACE). Methods: (Non-)responders were categorized using size-based RECIST 1.1 and WHO criteria, enhancement-based mRECIST EASL LI-RADS Treatment Response Algorithm (LR-TRA). outcomes overall survival (OS), progression-free (PFS), time...
M2-like macrophages promote tumor growth and cancer immune evasion. This study used an in vitro model to investigate how hypoxia metabolism affect macrophage polarization. Liver cells (HepG2 VX2) (THP1) were cultured under hypoxic (0.1% O
Purpose: To identify disease-specific profiles comprising patient characteristics and imaging biomarkers on contrast-enhanced (CE)-computed tomography (CT) that enable the non-invasive prediction of hepatopulmonary shunt fraction (HPSF) in patients with hepatocellular carcinoma (HCC) before resin-based transarterial radioembolization (TARE). Patients Methods: This institutional review board-approved (EA2/071/19) retrospective study included 56 HCC recommended for TARE. All received...
Histological microvascular invasion (MVI) is a risk factor for poor survival and early recurrence in hepatocellular carcinoma (HCC) after surgery. Its prognostic value the setting of locoregional therapies (LRT), where no tissue samples are obtained, remains unknown. This study aims to establish CT-derived indices indicative MVI on liver MRI with superior soft contrast evaluate their association patient ablation via interstitial brachytherapy (iBT) versus iBT combined prior conventional...
Very small superparamagnetic iron oxide nanoparticles (VSOPs) show diagnostic value in multiple diseases as a promising MRI contrast agent. Macrophages predominantly ingest VSOPs, but the mechanism remains unclear. This study identifies differences VSOP uptake between pro-inflammatory M1 and anti-inflammatory M2 macrophages explores role of pericellular glycocalyx. Glycosaminoglycans (GAG) synthesis activities glycocalyx for M1/M2-like were assessed by RT-qPCR, Click-iT reaction, WGA-FITC...
Introduction: Given the metachronous and multifocal occurrence of hepatocellular carcinoma (HCC) colorectal cancer metastases in liver (CRLM), this study aimed to compare intrahepatic progression patterns after computed tomography (CT)-guided high dose-rate brachytherapy. Patients methods: This retrospective analysis included 164 patients (114 HCC, 50 CRLM) treated with brachytherapy between January 2016 2018. received multiparametric magnetic resonance imaging (MRI) before, about 8 weeks...
Wir stellen den Fall eines 60-jährigen Patienten unserer Klinik mit am ehesten kongenitaler Herniation des kompletten rechten Leberlappens mitsamt der Gallenblase nach intrathorakal vor. Eine laparoskopische intrathorakale Cholezystektomie aufgrund einer rechtsseitigen Zwerchfellhernie wurde (medline: „intrathoracic cholecystectomy“) zuvor erst einmal beschrieben (Pullido J et al, JSLS, 2011 Oct-Dec;15(4):546 – 9).
SUMMARY: Patients with renal disease often develop accelerated atherosclerosis resulting in more frequent cardiovascular complications compared to the general population. It has been suggested that peroxidation of low density lipoprotein (LDL) contributes pathogenesis and glomerulosclerosis. The present study aimed investigate phosphatidylcholine hydroperoxide (PC‐OOH) content LDL patients chronic failure (CRF) on haemodialysis (HD). Plasma was obtained from healthy volunteers ( n = 20; age...