A5029673968- Radiation Dose and Imaging
- Advanced X-ray and CT Imaging
- Medical Imaging Techniques and Applications
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Radiology practices and education
- Liver Disease and Transplantation
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Advanced Radiotherapy Techniques
- Organ Transplantation Techniques and Outcomes
- Infrared Thermography in Medicine
- COVID-19 and healthcare impacts
- Advanced MRI Techniques and Applications
- Ultrasound in Clinical Applications
- Ultrasound Imaging and Elastography
- MRI in cancer diagnosis
- Aortic Disease and Treatment Approaches
- COVID-19 diagnosis using AI
- Aortic aneurysm repair treatments
- Healthcare cost, quality, practices
- Traumatic Ocular and Foreign Body Injuries
- Neuroendocrine Tumor Research Advances
- Renal cell carcinoma treatment
- Lung Cancer Diagnosis and Treatment
Charité - Universitätsmedizin Berlin
2016-2025
Freie Universität Berlin
2018-2024
Humboldt-Universität zu Berlin
2017-2024
University Medical Center Freiburg
2024
Society of Interventional Radiology
2022
Berlin Institute of Health at Charité - Universitätsmedizin Berlin
2022
Ludwig-Maximilians-Universität München
2021
MSB Medical School Berlin
2017-2019
Ihre-Radiologen
2016
Humboldt State University
2015
Patients with increased liver stiffness have a higher risk of developing cancer, however, the role fluid-solid tissue interactions and their contribution to tumor malignancy remains elusive. Tomoelastography is novel imaging method for mapping quantitatively solid-fluid properties soft tissues in vivo. It provides high resolution thus has clear clinical applications. In this work we used tomoelastography 77 participants, total 141 focal lesions different etiologies, investigate contributions...
Abstract This CIRSE Standards of Practice document is aimed at interventional radiologists and provides best practices for performing liver regeneration therapies prior to major hepatectomies, including portal vein embolization, double embolization venous deprivation. It has been developed by an expert writing group under the guidance Committee. encompasses all clinical technical details required perform therapies, revising indications, contra-indications, outcome measures assessed,...
Abstract Background We assessed the safety and efficacy of computed tomography (CT)-guided high-dose-rate (HDR) brachytherapy in treating hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT). Methods From January 2010 to 2022, 56 patients (median age 67.5 years) HCC PVTT underwent 64 procedures. was further classified according Japan liver cancer study group into VP1–VP4. Tumor response evaluated by cross-sectional imaging 6 weeks after CT-guided HDR every 3 months...
Abstract Background To investigate whether liver venous deprivation (LVD) as simultaneous, portal vein (PVE) and right hepatic embolization offers advantages in terms of hypertrophy induction before extended hepatectomy non-cirrhotic liver. Materials Methods Between June 2018 August 2019, 20 patients were recruited for a prospective, non-randomized study to the efficacy LVD. After screening 134 treated using PVE alone from January 2015 14 directly matched pairs regarding tumor entity...
Besides diagnostic imaging devices, in particular computed tomography (CT) and magnetic resonance (MRI), numerous reading workstations contribute to the high energy consumption of radiological departments. It was investigated whether switching off after core working hours can relevantly lower considering both ecological economical aspects. calculating different theoretical scenarios, we measured power 3 our department over a 6-month period under routine conditions another during which users...
Transjugular intrahepatic portosystemic shunt (TIPS) is a catheter-based, minimally invasive procedure to reduce portal hypertension. The aim of the study was investigate dysfunction and mortality after TIPS identify factors associated with these events.
Rising numbers of computed tomography (CT) examinations worldwide have led to a focus on dose reduction in the latest developments CT technology. Iterative reconstruction (IR) models bear potential effectively reduce while maintaining adequate image quality.To assess impact adaptive statistical iterative (ASIR) technique and quality dedicated whole body (WBCT) protocol for trauma patients.A total 122 subjects with multiple was prospectively included our study. Subjects who had undergo WBCT...
Background/Aim: Thermal-ablative therapies are limited to tumors of 3-4 cm diameter. The purpose this study was evaluate the local tumor control (LTC) CT-guided High-Dose-Rate-Brachytherapy (CT-HDRBT) for ablation cholangiocarcinomas (CCA) ≥4 compared smaller tumors. Patients and Methods: Sixty-one patients (tumors: 142, interventions: 91) were treated from March 2008 January 2017. LTC, progression-free survival (PFS) overall (OS) after first CT-HDRBT identified two subgroups (A:<4 cm,...
Abstract Objectives Data from radiological departments provide important information on overall quantities of medical care provided. With this study we used a comprehensive analysis examinations as surrogate marker to quantify the effect different COVID-19 waves Methods Radiological examination volumes during infection were compared among each other well time-matched control periods pre-pandemic years using locally weighted scatterplot smoothing negative binominal regression models. Results...
Background During transarterial chemoembolization (TACE), cone-beam computed tomography (CBCT) can be used for tumor and feeding vessel detection as well postembolization CT imaging. However, there will additional radiation exposure from CBCT. Purpose To evaluate the dose raised through CBCT-assisted guidance in comparison to TACE procedures guided with pulsed digital subtraction angiography (DSA) alone. Material Methods In 70 of 140 consecutive patients undergoing liver cancer, CBCT was...
Tumour response in lung cancer treatment is monitored by measuring lesion size computed tomography (CT). Spectral CT (SCT) offers additional information on tumour tissue besides morphology. We evaluated SCT iodine content (IC) and performed spectral slope analysis to assess the of non-small-cell (NSCLC) chemoradiotherapy (CRT).Eighty-three patients with advanced NSCLC treated CRT prospectively underwent single-phase, contrast-enhanced SCT. Evaluation all included (RECIST 1.1), quantitative...
<b>Purpose:</b> To assess how ASIR (adaptive statistical iterative reconstruction) contributes to dose reduction and affects image quality of non-contrast cranial computed tomography (cCT). <b>Materials Methods:</b> Non-contrast emergency CT scans the head acquired in 177 patients were evaluated. The processed using four different protocols: Group A (control): 120 kV, FBP (filtered back projection) n = 71; group B1: scan reconstruction performed with 20 % (blending 80 FBP), 86; B2: raw data...
This study aims to better characterize potential responders of Y-90-radioembolization at baseline through analysis clinical variables and contrast enhanced (CE) MRI tumor volumetry in order adjust therapeutic regimens early on improve treatment outcomes.Fifty-eight HCC patients who underwent our center between 10/2008 02/2017 were retrospectively included. Pre- post-treatment target lesion volumes measured as total volume (TTV) enhancing (ETV). Survival was performed with Cox regression...
Background Virtual monochromatic images (VMI) generated using spectral computed tomography (CT) are promising recently available tools to improve diagnostic performance in oncologic patients. Purpose To investigate if virtual datasets suitable for clinical routine use patients with hypervascularized abdominal tumors. Material and Methods A total of 41 hepatocellular carcinoma (HCC), renal cell (RCC), or neuroendocrine tumors (NET) were enrolled the study; 451 CT series analyzed. In an...
Abstract Metal artifacts notoriously pose significant challenge in computed tomography (CT), leading to inaccuracies image formation and interpretation. Artifact reduction tools have been designed improve cone beam (CBCT) quality by reducing caused certain high-density materials. artifact (MAR) are specific algorithms that applied during reconstruction minimize or eliminate degrading CBCT images. The purpose of the study is evaluate effect a MAR algorithm on performed for evaluating patients...
Purpose As a supra-regional level-I trauma center, we evaluated computed tomography (CT) acquisitions of polytraumatized patients for quality and dose optimization purposes. Adapted statistical iterative reconstruction [(AS)IR] levels, tube voltage reduction as well split-bolus contrast agent (CA) protocol were applied. Materials Methods 61 split into 3 different groups that differed with respect to (120 – 140 kVp) level applied ASIR (ASIR 20 50 %). The CT included native acquisition the...
Background Endovascular aneurysm repair (EVAR) requires lifelong surveillance by computed tomography angiography (CTA). This is attended a substantial accumulation of radiation exposure. Iterative reconstruction (IR) has been introduced to approach dose reduction. Purpose To evaluate adaptive statistical iterative (ASIR) at different levels tube voltage concerning image quality and reduction potential in follow-up post EVAR. Material Methods One hundred CTAs 67 patients with EVAR were...