- Radiation Therapy and Dosimetry
- Cardiac Arrhythmias and Treatments
- Sarcoma Diagnosis and Treatment
- Genetic factors in colorectal cancer
- Atrial Fibrillation Management and Outcomes
- Bone Tumor Diagnosis and Treatments
- Advanced Radiotherapy Techniques
- Parathyroid Disorders and Treatments
- Cardiac electrophysiology and arrhythmias
- Thyroid and Parathyroid Surgery
- Cardiac pacing and defibrillation studies
- Meningioma and schwannoma management
- Glioma Diagnosis and Treatment
- Management of metastatic bone disease
- Boron Compounds in Chemistry
- Pancreatic and Hepatic Oncology Research
- Anorectal Disease Treatments and Outcomes
- Cancer Genomics and Diagnostics
- Ocular Oncology and Treatments
- Head and Neck Surgical Oncology
- Cancer Diagnosis and Treatment
- Pelvic floor disorders treatments
- Neuroendocrine Tumor Research Advances
- Effects of Radiation Exposure
- Multiple and Secondary Primary Cancers
University Hospital Carl Gustav Carus
2006-2024
TU Dresden
2022-2024
University of Basel
2021
University Hospital of Basel
2021
Paul Scherrer Institute
2011-2020
Helios Hospital Schwerin
2019-2020
Helios Kliniken
2020
Kliniken Essen-Mitte
2019-2020
St. Josef-Hospital
2020
Proton (Malaysia)
2014-2020
In the search for endogenous cardiac glycosides, two different inhibitors of sodium pump have been isolated from bovine adrenals. Inhibitor A with a molecular mass 600 Da and UV maximum at 250 nm was purified 16 kg The pure substance (<1 ng) inhibited human red blood cells an affinity similar to that ouabain, yet it cross-reacted antibodies against bufadienolide proscillaridin but not cardenolide ouabain. slightly more hydrophilic than ouabain on RP-C18 high pressure liquid chromatography....
Skull-base chondrosarcoma (ChSa) is a rare disease, and the prognostication of this disease entity ill defined.We assessed long-term local control (LC) results, overall survival (OS), prognostic factors skull-base ChSa patients treated with pencil beam scanning proton therapy (PBS PT). Seventy-seven (male, 35; 46%) histologically confirmed were at Paul Scherrer Institute. Median age was 38.9 years (range, 10.2-70.0y). delivered dose 70.0 GyRBE 64.0-76.0 GyRBE). LC, OS, toxicity-free (TFS)...
The effect of dietary calcium on the cholic acid-induced colon cell proliferative response was investigated with C57BL/6J mice. control diets were formulated basis AIN-76 diet levels set at 0.1, 0.5 or 1.0% by weight and ratio Ca:P approximately 1:1. Cholic acid added 0.1% 0.25% weight. cytokinetic parameters colons evaluated after 2 weeks feeding metaphase arrest technique autoradiography. Mitotic activity found to monotonically decrease increasing level from 0.1 for both groups, acid-fed...
BackgroundThe incidence of atrial fibrillation (AF) after ablation a cavotricuspid isthmus (CTI)–dependent flutter (AFL) is high.ObjectiveThe purpose this study was to test the hypothesis that AFL and AF may be initiated by pulmonary vein triggers. This prospective randomized trial tested efficacy standalone isolation (PVI) in patients with but without AF.MethodsPatients documented were randomly assigned 1 3 treatment groups: (1) antiarrhythmic drugs (AAD), (2) CTI ablation, or (3)...
Pancreatic endocrine tumors (PETs) are characterized by the presence of hormone syndromes. Reports focusing on calcitonin-secreting PET (CTsPETs) very rare. This study aimed to define a CTsPET-associated syndrome in regard chemical, anatomical, and developmental aspects.A computerized MEDLINE search was conducted under items: "pancreatic tumor," "calcitonin," "neuroendocrine pancreatic "pancreas." Results clinical, histopathological, immunohistochemical, biochemical assessments all patients...
Case-control studies report a dose-dependent increased risk of skin cancer in users hydrochlorothiazide (HCTZ) vs. nonusers. The degree to which other thiazides and thiazide-like diuretics (TZs) are associated with is less certain.To assess the new different TZs compared calcium channel blockers (CCBs).We conducted cohort study using UK primary-care database (1998-2017), including 271 154 TZ [87·6% bendroflumethiazide (BFT), 5·8% indapamide 3·6% HCTZ] 275 263 CCB users. outcomes were basal...
The aim of this study was to describe and compare clinical characteristics outcomes in critically ill septic patients with without COVID-19.
Background: Pancreatic cancer is among the most dismal of human malignancies. The 5-year survival rate lower than 5%. identification precursor lesions would be main step to improve this fatal outcome. One are called pancreatic intraepithelial neoplasia (PanIN) and graduated in grade 1 3, whereas 3 classified as carcinoma situ. Currently, no reliable, noninvasive imaging technique (e.g., ultrasound, computed tomography, magnet resonance imaging) exists verify PanINs. Methods: Recently, a...