Elias Karakas

ORCID: 0000-0001-7202-9142
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About
Contact & Profiles
Research Areas
  • Thyroid and Parathyroid Surgery
  • Parathyroid Disorders and Treatments
  • Head and Neck Anomalies
  • Pancreatic and Hepatic Oncology Research
  • Voice and Speech Disorders
  • Thyroid Cancer Diagnosis and Treatment
  • Sympathectomy and Hyperhidrosis Treatments
  • Genetic Syndromes and Imprinting
  • Pancreatitis Pathology and Treatment
  • Tracheal and airway disorders
  • Thyroid Disorders and Treatments
  • Airway Management and Intubation Techniques
  • Salivary Gland Tumors Diagnosis and Treatment
  • Erythrocyte Function and Pathophysiology
  • Gastric Cancer Management and Outcomes
  • Pancreatic function and diabetes
  • Dysphagia Assessment and Management
  • Cancer Research and Treatments
  • Oropharyngeal Anatomy and Pathologies
  • Minimally Invasive Surgical Techniques
  • Pituitary Gland Disorders and Treatments
  • Cancer Cells and Metastasis
  • Platelet Disorders and Treatments
  • Esophageal and GI Pathology
  • Colorectal Cancer Treatments and Studies

Philipps University of Marburg
2007-2024

Maria Hilf Krankenhaus
2018-2022

Kliniken Essen-Mitte
2014-2017

Helios Dr. Horst Schmidt Kliniken Wiesbaden
2013-2014

Eskişehir Osmangazi University
2014

Universitätsklinikum Aachen
2012

Universitätsklinikum Gießen und Marburg
2006-2010

Justus-Liebig-Universität Gießen
2008

Klinikum Arnsberg
2006

OBJECTIVE Primary hyperparathyroidism (pHPT)-related hypercalcemia is considered to represent a risk factor for the development of pancreatitis. We therefore explored whether mutations in genes that were previously identified increase pancreatitis coexist cohort 826 patients with pHPT prospectively studied between 1987 and 2002. METHODS Among pHPT, 38 (4.6%). DNA was available from 25 (13 women/12 men, 16 acute pancreatitis/9 chronic pancreatitis). These individuals 50 without analyzed...

10.1111/j.1572-0241.2007.01695.x article EN The American Journal of Gastroenterology 2008-02-01

The aim of this study was to evaluate a new surgical technique by the European Transoral Endoscopic Thyroidectomy Vestibular Approach (TOETVA) Study Group. This included 391 patients (47 [(12%]) male and 344 [(88%)] female) who had undergone endoscopic thyroid or parathyroid surgery via vestibular approach between February 2016 May 2022 at nine centers. data were analyzed with regard complications, time specimen retrieval. Overall, 376 (96.2%) TOETVA 15 (3.8%) transoral parathyroidectomy...

10.1007/s00268-023-06932-7 article EN cc-by World Journal of Surgery 2023-02-17

Background Epithelial and mesenchymal transitions (EMT) are essential for embryonic development progression of non-invasive tumor cells into malignant, metastatic carcinomas. During embryogenesis, the parathyroid glands develop from pharyngeal pouches migrate to their final destinations, densely enclosed by neural crest cells. In this study, we examined expression EMT markers Snail, Twist E-cadherin in normal benign malignant diseases. Methods Using immunohistochemistry, compared E-cadherin,...

10.1530/eje-08-0662 article EN European Journal of Endocrinology 2009-01-29

A relationship between primary hyperparathyroidism (pHPT) and pancreatitis has long been debated remains a rare epiphenomenon. In cohort of patients with pHPT mutations in the serine protease inhibitor Kazal type I (SPINK1) cystic fibrosis transmembrane conductance regulator (CFTR) genes, that increase risk for have already detected. Among identification additional pancreatitis-associtated Chymotrypsin C gene (CTRC) it became clear also protective genetic variants exist anionic trypsinogen...

10.1055/s-0030-1255106 article EN Experimental and Clinical Endocrinology & Diabetes 2010-07-12

10.1007/s40618-019-01149-9 article EN Journal of Endocrinological Investigation 2020-01-28

Abstract Transoral endoscopic thyroidectomy vestibular approach (TOETVA) is an upcoming surgical technique with the aim to optimize cosmetic outcome avoiding visible scars in neck. However, transoral access bears risk of contamination and microbial allocation from mouth into thyroid region. Therefore, some authors recommend extended antibiotic therapy up 7 days after surgery. Our was evaluate infection rates parameters before surgery suggest a viable safe routine Prospectively collected data...

10.1007/s13304-021-01191-4 article EN cc-by Updates in Surgery 2021-10-20

After parathyroidectomy (PTX), hungry bone syndrome leads to hypocalcemia due remineralization. The aim of this pilot study was analyze changes in markers metabolism patients with secondary hyperparathyroidism (sHPT) after PTX and correlate these pain measured a validated questionnaire.All who underwent for sHPT between March 2010 February 2012 at out institution were included prospective observational study. At the day before surgery on 3rd thereafter, levels parathyroid hormone (PTH),...

10.1159/000486172 article EN European Surgical Research 2018-01-01

Background: Primary hyperparathyroidism (pHPT) related hypercalcaemia is considered to represent a risk factor for the development of pancreatitis. We therefore explored whether mutations in calcium-sensing receptor gene (CASR) coding (CaR), an essential regulator calcium homeostasis parathyroid chief cells, exist cohort patients with pHPT and

10.1055/s-2007-981455 article EN Experimental and Clinical Endocrinology & Diabetes 2007-09-12
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