A5073507924- Pituitary Gland Disorders and Treatments
- Pancreatic and Hepatic Oncology Research
- Neuroscience and Neuropharmacology Research
- Alzheimer's disease research and treatments
- RNA modifications and cancer
- Neuroinflammation and Neurodegeneration Mechanisms
- Meningioma and schwannoma management
- Sarcoma Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Thyroid Disorders and Treatments
- Spinal Cord Injury Research
- Retinal Development and Disorders
- Hydrogen's biological and therapeutic effects
- Neuroblastoma Research and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Viral-associated cancers and disorders
- Ion Channels and Receptors
- Inflammatory Biomarkers in Disease Prognosis
- Neuroendocrine regulation and behavior
- Bone Tumor Diagnosis and Treatments
- Adrenal and Paraganglionic Tumors
- Organ and Tissue Transplantation Research
- Cellular transport and secretion
- Phagocytosis and Immune Regulation
- Mycobacterium research and diagnosis
Kunming Institute of Zoology
2023
South China Normal University
2016-2020
Inner Mongolia People's Hospital
2020
Xiamen University
2020
Tianjin Medical University Cancer Institute and Hospital
2020
The Affiliated Yongchuan Hospital of Chongqing Medical University
2015-2019
Chongqing Medical University
2015-2019
Jilin University
2017
First Hospital of Jilin University
2017
Wenzhou Medical University
2006
Ample evidence has suggested the stress etiology of depression, but underlying mechanism is not fully understood yet. Here, we report that chronic social defeat (CSDS) attenuates excitatory output claustrum (CLA) to prelimbic cortex (PL) through dynorphin/κ-opioid receptor (KOR) signaling, being critical for depression-related behaviors in male mice. The CSDS preferentially impairs from CLA onto parvalbumin (PV) PL, leading PL micronetwork dysfunction by disinhibiting pyramidal neurons...
Microglial activation is an essential pathological mechanism of spinal cord ischemia-reperfusion injury (SCIRI). Previous studies showed dexmedetomidine (DEX) could alleviate SCIRI while the was not clear. This study aims to investigate role DEX in microglial and clarify underlying mechanism.The motion function mice quantified using Basso Mouse Scale for Locomotion. The expression long non-coding RNA (lncRNA) small nucleolar host gene 14 (SNHG14) determined by qRT-PCR. high-mobility group...
Genetic and biochemical studies have focused on the role of amyloid β protein in pathogenesis Alzheimer's disease. In comparison, physiological roles its precursor protein, (APP), synaptic network activity is less well studied. Using an APP knockout (APP−/−) mouse model, we show that duration UP state, which a key feature cortical integration occurring predominantly during slow-wave sleep, significantly increased prefrontal cortex (PFC) absence APP. This was accompanied by specific reduction...
Only a few cases of double or multiple pituitary adenomas have previously been reported in the literature; however, isolated adrenocorticotropic hormone (ACTH)-secreting are even more rare. The present study reports rare case 50-year-old female patient who presented with typical clinical features Cushing's disease and was diagnosed ACTH-secreting adenomas. Endocrinological examination revealed an ACTH-producing adenoma, preoperative magnetic resonance imaging (MRI) demonstrated microadenoma...
To identify the subtype of transient receptor potential (TRPs) channel involved in stretch-induced injury human brain microvascular endothelial cells (HBMEC) and to explore mechanism responsible for eNOS expression. TRPs expression was examined by Western blot immunocytofluoresence cultured HBMEC. Mechanical stretch performed mini-type multi-functional bio-impact machine. The levels free calcium ion were flow cytometry. detected blot. mRNA protein TRPV4 HBMEC qRT-PCR, immunocytofluoresence....
Currently, there are few studies on the characteristics of lymph node metastasis in central region patients with preoperative negative (cN0) papillary thyroid carcinoma (PTC) coexistent Hashimoto's thyroiditis (HT). There is still a significant controversy whether to perform prophylactic compartment dissection for T1/T2 cN0 PTC. Therefore, we aimed investigate and risk factors PTC (T1 or T2 stage) coexists HT.From Jun. 2015 Apr. 2019, clinicopathological data 354 stage admitted tumor surgery...
Oropharyngeal squamous cell carcinoma (OPSCC) is a kind of head and neck, its incidence on the rise in recent years. A variety prognostic markers for OPSCC have been reported many studies, but they are expensive or difficult to obtain. So, we retrospectively studied significance cytokeratin 19 soluble fragment (Cyfra21-1) patients with OPSCC, order provide theoretical basis accurate prognosis assessment.A retrospective analysis clinicopathological data 85 concurrent radiotherapy chemotherapy...
Oropharyngeal cancer (OPC) is a type of head and neck squamous cell cancer, the incidence which has increased in recent years. Many studies have reported variety prognostic markers OPC, but they are either expensive or difficult to obtain. Therefore, we retrospectively studied value circulating neutrophil count (CNC) patients with aim providing theoretical basis for further stratification.The clinicopathological data 153 diagnosed OPC from January 2010 June 2017 were analyzed. The CNC each...
Alveolar soft part sarcoma (ASPS) is a kind of extremely rare malignant tissue sarcoma, which was first discovered and defined by American scholars in 1952. Its main manifestation painless slow growth mass, distant metastasis often occurs lung, bone, brain, liver with poor prognosis. In recent years, the accumulation number cases development related technology, diagnosis treatment ASPS have been improved greatly. However, primary intracranial still rare, this paper reviews progress ASPS,...