A5004595325- Neural dynamics and brain function
- Neuroscience and Neuropharmacology Research
- Retinal Development and Disorders
- Neuroscience and Neural Engineering
- Photoreceptor and optogenetics research
- Visual perception and processing mechanisms
- EEG and Brain-Computer Interfaces
- Cognitive Science and Education Research
- Reading and Literacy Development
- Municipal Solid Waste Management
- Advanced Optical Sensing Technologies
- Neural and Behavioral Psychology Studies
- Neurobiology of Language and Bilingualism
- Medical Imaging Techniques and Applications
- Microplastics and Plastic Pollution
- Zebrafish Biomedical Research Applications
- Advanced Memory and Neural Computing
- Recycling and Waste Management Techniques
- Ocular and Laser Science Research
- Memory and Neural Mechanisms
- Action Observation and Synchronization
Open Ephys Production Site (Portugal)
2023-2024
Synapse (Netherlands)
2016-2024
Netherlands Institute for Neuroscience
2016-2024
Utrecht University
2024
University of Auckland
2023
Royal Netherlands Academy of Arts and Sciences
2022
University of Amsterdam
2014
What are the limits of unconscious language processing? Can circuits process simple grammatical constructions unconsciously and integrate meaning several unseen words? Using behavioural priming electroencephalography (EEG), we studied a specific rule-based linguistic operation traditionally thought to require conscious cognitive control: negation valence. In masked paradigm, two words were successively (Experiment 1) or simultaneously presented 2), modifier ('not'/'very') an adjective (e.g....
Behavioral neuroscience faces two conflicting demands: long-duration recordings from large neural populations and unimpeded animal behavior. To meet this challenge, we developed ONIX, an open-source data acquisition system with high throughput (2GB/sec) low closed-loop latencies (<1ms) that uses a novel 0.3 mm thin tether to minimize behavioral impact. Head position rotation are tracked in 3D used drive active commutation without torque measurements. ONIX can acquire combinations of passive...
During early development, before the eyes open, synaptic refinement of sensory networks depends on activity generated by developing neurons themselves. In mouse visual system, retinal cells spontaneously depolarize and recruit downstream to bursts activity, where number recruited determines resolution retinotopic refinement. Here we show that during second post-natal week in cortex, somatostatin (SST)-expressing interneurons control recruitment retinally driven spontaneous activity....
Synaptic inputs to cortical neurons are highly structured in adult sensory systems, such that neighboring synapses along dendrites activated by similar stimuli. This organization of synaptic inputs, called clustering, is required for high-fidelity signal processing, and clustered can already be observed before eye opening. However, how emerge during development unknown. Here, we employed concurrent vivo whole-cell patch-clamp dendritic calcium imaging map spontaneous layer 2/3 the mouse...
Behavioral neuroscience faces two conflicting demands: long-duration recordings from large neural populations and unimpeded animal behavior. To meet this challenge we developed ONIX, an open-source data acquisition system with high throughput (2 GB s
Abstract Synaptic inputs to cortical neurons are highly structured in adult sensory systems, such that neighboring synapses along dendrites activated by similar stimuli. This organization of synaptic inputs, called clustering, is required for high-fidelity signal processing, and clustered can already be observed before eye opening. However, how emerge during development unknown. Here, we employed concurrent vivo whole-cell patch clamp dendritic calcium imaging map spontaneous layer 2/3 the...
Long-term manipulation of activity in the neonatal rodent brain can help us understand healthy development, but also involves a set challenges unique to animal. As pups are small, cannot be separated from their mother for long periods time, and must housed nest, many traditional techniques unusable during first two postnatal weeks.Here, we describe use magnetic resonance induction allow wireless chronic optogenetic spontaneous mouse second week.Pups were implanted with lightweight receiver...
Summary During early development, even before the senses are active, bursts of activity travel across nervous system. This spontaneously generated drives refinement synaptic connections, preparing young networks for patterned sensory input. Synaptic fine-tuning relies not only on presence spontaneous activity, but also specific characteristics these patterns, such as their frequency, amplitude and synchronicity. Here, we provide evidence that crucial shaped by relative balance excitation...
Synaptic inputs to cortical neurons are highly structured in adult sensory systems, such that neighboring synapses along dendrites activated by similar stimuli. This organization of synaptic inputs, called clustering, is required for high-fidelity signal processing, and clustered can already be observed before eye opening. However, how emerge during development unknown. Here, we employed concurrent vivo whole-cell patch clamp dendritic calcium imaging map spontaneous layer 2/3 the mouse...
Synaptic inputs to cortical neurons are highly structured in adult sensory systems, such that neighboring synapses along dendrites activated by similar stimuli. This organization of synaptic inputs, called clustering, is required for high-fidelity signal processing, and clustered can already be observed before eye opening. However, how emerge during development unknown. Here, we employed concurrent vivo whole-cell patch-clamp dendritic calcium imaging map spontaneous layer 2/3 the mouse...
Event Abstract Back to Qualitatively different neural mechanisms for conscious and subliminal multiple word integration Simon Van Gaal1, 2*, Lionel Naccache3, Julia Meuwese4, Anouk Loon4, Alexandra Leighton4, Laurent Cohen3 Stanislas Dehaene5 1 University of Amsterdam, Department Psychology, The Netherlands 2 Donders Institute Brain, Cognition Behavior, the Netherlands, 3 INSERM, ICM Research Center, UMRS 975, France 4 5 Collège de France, Although great progress has been made in...
Synaptic inputs to cortical neurons are highly structured in adult sensory systems, such that neighboring synapses along dendrites activated by similar stimuli. This organization of synaptic inputs, called clustering, is required for high-fidelity signal processing, and clustered can already be observed before eye opening. However, how emerge during development unknown. Here, we employed concurrent vivo whole-cell patch clamp dendritic calcium imaging map spontaneous layer 2/3 the mouse...