- Congenital Heart Disease Studies
- Aortic Disease and Treatment Approaches
- Cardiac Valve Diseases and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Infective Endocarditis Diagnosis and Management
- Cardiac and Coronary Surgery Techniques
- Coronary Artery Anomalies
- Vascular anomalies and interventions
- Venous Thromboembolism Diagnosis and Management
- Aortic aneurysm repair treatments
- Meningioma and schwannoma management
- Cardiovascular Issues in Pregnancy
- Cardiovascular Conditions and Treatments
- Cardiovascular Syncope and Autonomic Disorders
- Health Systems, Economic Evaluations, Quality of Life
- Connective tissue disorders research
- Cardiac Health and Mental Health
- Tracheal and airway disorders
- Neurofibromatosis and Schwannoma Cases
- Cardiac pacing and defibrillation studies
- Soft tissue tumor case studies
- Brain Metastases and Treatment
University Medical Center Groningen
2018-2024
University of Groningen
2018-2024
University Medical Center
2013-2024
Maastricht University
2005-2024
Dialyse Centrum Groningen
2024
Society of Thoracic Surgeons
2018-2020
University Medical Center Utrecht
2018
Maastricht University Medical Centre
2005-2016
VieCuri Medisch Centrum
2010
Cardiovascular Institute Hospital
2008
Abstract: Some patients in need of hemodynamic support do not respond to intra‐aortic balloon pump (IABP) therapy. Hemodynamic stability can then be obtained by a more potent cardiac assist device, like the Impella catheter pump. Whether additional IABP provide optimal myocardial conditions is examined this study. Seven sheep were implemented with and Impella. An acute infarction was induced. performance assessed during baseline, individually, combined plus support. The provided reduction...
Abstract OBJECTIVES Anomalous aortic origin of a coronary artery (AAOCA) is group rare congenital heart defects with various clinical presentations. The lifetime-risk an individual living AAOCA unknown, and data from multicentre registries are urgently needed to adapt current recommendations guide optimal patient management. European Registry (EURO-AAOCA) aims assess differences regard management between centres. METHODS EURO-AAOCA prospective, registry including 13 Herein, we evaluated in...
This is a multicenter, prospective, randomized controlled trial to determine the effect of add-on arrhythmia surgery on health-related quality life during 1-year follow-up cardiac patients with atrial fibrillation.150 documented fibrillation were randomly assigned undergo or without surgery. Patients completed questionnaires, comprising RAND 36-item Health Survey 1.0 (SF-36), Multidimensional Fatigue Inventory-20 (MFI-20) and EuroQoL (EQ-5D VAS) at baseline 3, 6, 12 months following...
The “hybrid” approach to multivessel coronary artery disease combines surgical left internal thoracic (LITA) anterior descending (LAD) bypass grafting and percutaneous intervention of the remaining lesions. Ideally, LITA LAD graft is performed in a minimally invasive fashion. This review aims clarify place hybrid revascularization (HCR) current therapeutic armamentarium against disease. Eighteen studies including 970 patients were included for analysis. postoperative patency varied between...
Abstract Background Neonates with critical congenital heart disease (CCHD) undergoing cardiac surgery cardiopulmonary bypass (CPB) are at risk of brain injury that may result in adverse neurodevelopment. To date, no therapy is available to improve long-term neurodevelopmental outcomes CCHD neonates. Allopurinol, a xanthine oxidase inhibitor, prevents the formation reactive oxygen and nitrogen species, thereby limiting cell damage during reperfusion reoxygenation heart. Animal neonatal...
Intrapericardial (IPC) delivery of antiarrhythmic agents is an appealing idea to increase the therapeutic width and reduce side effects drugs, particularly in thin atria. The aim this study was determine IPC versus intravenous (IV) d,l-sotalol flecainide infusion on transmural atrial electrophysiology sustained fibrillation (AF) goat.Effects IV sotalol epi- endocardial electrophysiology, ECG, tissue drug concentrations were studied goats without with persistent AF (>24 hours). Epicardial...
Current management guidelines for ascending thoracic aortic aneurysms (aTAA) recommend intervention once or sinus diameter reaches 5-5.5 cm shows a growth rate of >0.5 cm/year estimated from echo/CT/MRI. However, many aTAA dissections (aTAAD) occur in vessels with diameters below the surgical threshold <55 mm. Moreover, during repair surgeons observe and experience considerable variations tissue strength, thickness, stiffness that appear not fully explained by patient risk factors. To...
The number of patients with an arterial switch operation (ASO) for transposition the great arteries (TGA) is steadily growing; limited information available regarding clinical course in current era.
BackgroundThe aim of this study was to evaluate early and mid-term outcomes (mortality prosthetic valve reintervention) after mitral replacement with 15- 17-mm mechanical prostheses.MethodsA multicenter, retrospective cohort performed among patients who underwent a prosthesis at 6 congenital cardiac centers: 5 in The Netherlands 1 the United States. Baseline, operative, follow-up data were evaluated.ResultsMitral 61 infants (15 mm, n = 17 [28%]; 16 18 [29%]; 26 [43%]), whom 27 (47%) admitted...
Conventional open harvest of the great saphenous vein (GSV) during CABG results in approximately 7% donor-site complications. Using endoscopic harvesting (EVH) full GSV length can be harvested through a 3 cm incision. This nonsystematic review discusses several key issues concerning EVH, based on an extensive Pubmed search. Found studies show that EVH reduced number wound complications, less postoperative pain, earlier mobilisation, hospital stay, and is more cost-effective. Initial did not...
This study was performed to assess the cost-effectiveness of concomitant ablation surgery (AS) compared regular cardiac in atrial fibrillation (AF) patients over a one-year follow-up. Cost analysis from societal perspective alongside prospective, randomised, double-blinded, multicentre trial. One hundred and fifty with documented AF were randomly assigned undergo or without AS. thirty-two included study. All costs (medical non-medical) measured during Costs data combined quality adjusted...
Objectives We sought to determine the indications, type, and outcomes of reoperations on aortic root after repair tetralogy Fallot (TOF). Methods Eleven centers belonging European Congenital Heart Surgeons Association contributed data collection process. included 36 patients who underwent surgical procedures root, including surgery valve ascending aorta, between January 1975 December 2017. Original diagnoses TOF-pulmonary stenosis (n = 18) atresia 18). The main indications for reoperation...
Abstract The etiology of nonimmune hydrops fetalis is extensive and includes genetic disorders. We describe a term‐born female neonate with late onset hydrops, that is, polyhydramnios, edema, congenital bilateral chylothorax. This newborn was successfully treated repetitive thoracocentesis, total parenteral feeding, octreotide intravenously finally surgical pleurodesis corticosteroids. A cause seemed plausible as the maternal history revealed fatal fetalis. homozygous truncating variant in...
We investigated the impact and predictive value of sinus rhythm at 12 months (SR12) on subscales three different HrQoL questionnaires: SF-36., EuroQoL MFI 20. Data 125 cardiac surgery patients with pre-operative AF from our previous randomized trial were used. Based their outcome divided in two groups: SR12 or follow up (non-SR12). All questionnaires self-administered pre-operatively 3 months, 6 after surgery. Synus rhytm was improvement SF36- mental score (MS, p = 0.021), Euro-QoL-MS (p...
OBJECTIVESWe investigated real-life oral anticoagulation (OAC) treatment after surgical ablation and examined its adherence to current recommendations. We also explored factors related OAC use preoperatively at follow-up.