Joana Domingues

ORCID: 0000-0003-0026-0075
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About
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Research Areas
  • Electrospun Nanofibers in Biomedical Applications
  • Wound Healing and Treatments
  • Education during COVID-19 pandemic
  • Essential Oils and Antimicrobial Activity
  • Diabetic Foot Ulcer Assessment and Management
  • Nanocomposite Films for Food Packaging
  • Retinal Imaging and Analysis
  • Retinal and Optic Conditions
  • Antimicrobial agents and applications
  • Graphene and Nanomaterials Applications
  • Ophthalmology and Visual Health Research
  • Dermatological and COVID-19 studies
  • Surgical Sutures and Adhesives
  • Mycobacterium research and diagnosis
  • Nanoparticles: synthesis and applications
  • Retinal Development and Disorders
  • Education Pedagogy and Practices
  • Healthcare Regulation
  • Visual perception and processing mechanisms
  • Environmental Sustainability and Education
  • RNA Interference and Gene Delivery
  • Advanced biosensing and bioanalysis techniques
  • Biosensors and Analytical Detection
  • Bacterial Genetics and Biotechnology
  • COVID-19 and healthcare impacts

University of Coimbra
2025

University of Minho
2021-2023

CeNTI (Portugal)
2020

Sociedade Portuguesa de Cardiologia
2019

Université de Toulouse
2015

Université Toulouse III - Paul Sabatier
2015

One of the most important measures implemented to reduce SARS-CoV-2 transmission has been use face masks. Yet, mask options available in market display a passive action against virus, not actively compromising its viability. Here, we propose overcome this limitation by incorporating antiviral essential oils (EOs) within polycaprolactone (PCL) electrospun fibrous mats be used as intermediate layers individual protection Twenty EOs selected based on their antimicrobial nature were examined for...

10.3390/pharmaceutics14020303 article EN cc-by Pharmaceutics 2022-01-27

Aims/Purpose: This work aims to assess the performance of an automatic method for segmenting lumen retinal arterioles from adaptive optics (AO) high‐resolution fundus images in comparison manual segmentation and its potential impact on determination neurovascular coupling (NVC) response. Methods: A total 944 (4x4 degrees) within macular region were acquired 30 healthy adults (age (m+/‐sd): 33.7+/‐11.2 yrs.) 15 type 1 Diabetes Mellitus (T1DM) patients (36.3+/‐13.3 yrs.), gender imaged eye...

10.1111/aos.17281 article EN Acta Ophthalmologica 2025-01-01

Aims/Purpose: This work aims to assess the performance of an automatic method for segmenting lumen retinal arterioles from adaptive optics (AO) high‐resolution fundus images in comparison manual segmentation and its potential impact on determination neurovascular coupling (NVC) response. Methods: A total 944 (4x4 degrees) within macular region were acquired 30 healthy adults (age (m+/‐sd): 33.7+/‐11.2 yrs.) 15 type 1 Diabetes Mellitus (T1DM) patients (36.3+/‐13.3 yrs.), gender imaged eye...

10.1111/aos.16978 article EN Acta Ophthalmologica 2025-01-01

Gram positive mycobacteria with a high GC content, such as the etiological agent of tuberculosis Mycobacterium tuberculosis, possess an outer membrane mainly composed mycolic acids (MAs), so-called mycomembrane, which is essential for cell. About thirty genes are involved in biosynthesis MAs, include hadA, hadB and hadC that encode dehydratases Fatty Acid Synthase type II (FAS-II) known to function heterodimers HadA-HadB HadB-HadC. The present study shows M. smegmatis cells remain viable...

10.1371/journal.pone.0145883 article EN cc-by PLoS ONE 2015-12-23

Chronic wounds (CW) have numerous entry ways for pathogen invasion and prosperity, which further damages host tissue hinders remodeling. Essential oils (EOs) exert quick efficient antimicrobial (AM) action, unlikely to induce bacterial resistance. Cinnamon leaf oil (CLO) is a well-studied EO with strong AM properties. In this work, CLO was added chitosan (Ch) polyvinyl alcohol (PVA) solutions. Ch natural cationic polysaccharide antibacterial, anti-inflammatory regenerative PVA adds...

10.3390/ciwc2020-06826 article EN cc-by 2020-05-13

Infected diabetic foot ulcers (DFUs) are a frequent and costly complication of diabetes, with limb amputation being highly prevalent worldwide. Even if treated, recurrence is frequent, pathogen clearance degenerated tissue recovery increasingly more difficult each time. Persistent pathogens such as Staphylococcus aureus Pseudomonas aeruginosa the main microbial inhabitants infected DFUs, often gaining antimicrobial-resistance to treatment [1]. Nanoparticle (NP)-mediated therapies may...

10.3390/ecb2021-10292 article EN cc-by 2021-06-01

In December 2019, a novel strain of coronavirus, SARS-CoV-2, was identified. Infected patients revealed symptoms fever, cough (dry), sore throat, and fatigue, which began manifesting after 5 days incubation. Hoping to prevent transmission, many countries adopted mandatory mask use in closed public spaces. However, most options display passive action against COVID-19. To overcome such restrictions, this work proposes the incorporation anti-viral essential oils (EOs) loaded onto nanofibrous...

10.3390/ecb2021-10253 article EN cc-by 2021-05-31
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