A5042929945- Electrospun Nanofibers in Biomedical Applications
- Wound Healing and Treatments
- Silk-based biomaterials and applications
- Essential Oils and Antimicrobial Activity
- Antimicrobial agents and applications
- Wine Industry and Tourism
- Horticultural and Viticultural Research
- Nanocomposite Films for Food Packaging
- Advanced Cellulose Research Studies
- Natural Fiber Reinforced Composites
- Antimicrobial Peptides and Activities
- Protein Hydrolysis and Bioactive Peptides
- Innovations in Concrete and Construction Materials
- Biopolymer Synthesis and Applications
- Nanoparticles: synthesis and applications
- Graphene and Nanomaterials Applications
- Tissue Engineering and Regenerative Medicine
- Enzyme-mediated dye degradation
- Infection Control and Ventilation
- Forest Insect Ecology and Management
- Probiotics and Fermented Foods
- Carbon and Quantum Dots Applications
- Natural Compound Pharmacology Studies
- Medical research and treatments
- Mechanical Engineering and Vibrations Research
University of Minho
2019-2024
Sogrape Vinhos (Portugal)
2021-2024
Heriot-Watt University
1998-2011
Chronic wounds (CW) create numerous entryways for pathogen invasion and prosperity, further damaging host tissue hindering its remodeling repair. Essential oils (EOs) exert quick efficient antimicrobial (AM) action, unlikely to induce bacterial resistance. Cinnamon leaf clove (CLO CO) display strong AM activity, namely against Staphylococcus aureus Pseudomonas aeruginosa. Chitosan (CS) is a natural biodegradable cationic polysaccharide, also widely known features. CS poly (vinyl alcohol)...
Quercus suber cork generates bioactive components, such as phenolic acids, terpenoids, and tannins, with excellent biological properties, including antioxidant, anti-inflammatory, antiaging activities. Aiming to design environmentally benign processes eliminate, or reduce, the use of toxic chemicals, we propose green extraction bioactives from using natural deep eutectic solvents (NADES). Several mixtures were developed, through mixture compounds, namely, lactic acid, glycerol, ethylene...
New approaches to deal with the growing concern associated antibiotic-resistant bacteria are emerging daily. Essential oils (EOs) natural antimicrobial substances great potential mitigate this situation. However, their volatile nature, in liquid-free form, has restricted generalized application biomedicine. Here, we propose use of cellulose acetate (CA)/polycaprolactone (PCL) wet-spun fibers as delivery platforms selected EOs fight infections caused by Staphylococcus aureus (S. aureus) and...
One of the most important measures implemented to reduce SARS-CoV-2 transmission has been use face masks. Yet, mask options available in market display a passive action against virus, not actively compromising its viability. Here, we propose overcome this limitation by incorporating antiviral essential oils (EOs) within polycaprolactone (PCL) electrospun fibrous mats be used as intermediate layers individual protection Twenty EOs selected based on their antimicrobial nature were examined for...
In this research, we propose to engineer a nanostructured mat that can simultaneously kill bacteria and promote an environment conducive healing for prospective wound care. Polyvinyl alcohol (PVA) cellulose acetate (CA) were combined at different polymer ratios (100/0, 90/10, 80/20% v/v), electrospun crosslinked with glutaraldehyde vapor. Crosslinked fibers increased in diameter (from 194 278 nm), retaining their uniform structure. Fourier-transform infrared spectroscopy thermal analyses...
ABSTRACT Poly(vinyl alcohol)/cellulose acetate (PVA/CA) films were prepared via a new method that combines principles from solvent casting and phase inversion. To guarantee some degree of flexibility, produced with higher percentage PVA compared to CA, 90/10 50/50. The antimicrobial peptide (AMP) LL37 was then anchored using dopamine as binding agent. Films characterized in terms functional groups, thermal stability, tensile strength, porosity, swelling, degradation (stability physiological...
Infection is a major issue in chronic wound care. Different dressings have been developed to prevent microbial propagation, but an effective, all-in-one (cytocompatible, antimicrobial and promoter of healing) solution still be uncovered. In this research, polyvinyl alcohol (PVA) nanofibrous mats reinforced with cellulose nanocrystal (CNC), at 10 20% v/v ratios, were produced by electrospinning, crosslinked glutaraldehyde vapor doped specialized peptides. Crosslinking increased the mats'...
Conductive and colored bacterial cellulose (BC) was developed by entrapment of polyaniline (PANi) onto dry BC membranes. The produced in situ green polymerization aniline Myceliophthora thermophila laccase at pH = 4, 25°C, the presence a mediator, 1-hydroxybenzotriazol (HBT), using two different reactors, water bath (WB) an ultrasonic (US). MALDI-TOF 1H NMR characterization experiment solutions confirmed efficient laccase. dried membranes with entrapped showed electrical conductive behavior...
The purpose of this research was to analyze the morphology, thermal and mechanical properties poly(vinyl alcohol) (PVA)-based electrospun mats reinforced with cellulose acetate (CA) or nanocrystalline (CNC) for potential applications in wound dressings. Bead-free water-stable nanofibers made blends PVA CA CNC were successfully produced crosslinked glutaraldehyde vapor. Crosslinking slightly increased nanofibers' diameters order 43 13% 80/20 PVA/CA PVA/CNC mats, respectively, while...
In the last years, chronic wounds have become more prevalent, leading to a huge burden on healthcare and social systems by requiring specialized protection. Indeed, wound dressings capable of assisting in healing process are urgent need. To that effect, nanofibrous with structure resembling extracellular matrix been engineered electrospinning from combinations poly(vinyl alcohol) (PVA) cellulose acetate (CA) optimized endure physiological media contact mechanical stress after crosslinking....
Understanding peptide adsorption kinetics onto biomaterial surfaces is crucial for developing wound treatments. This study aims to explore the influence of cellulose acetate (CA) and nanocrystals (CNC) on via quartz crystal microbalance with dissipation monitoring (QCM-D), using a cyclic peptide, Tiger 17, linear, Pexiganan. PVA was reinforced 10 20% w/v CA CNC, spin-coated QCM-D sensors, crosslinked glutaraldehyde. Films containing higher percentages cellulosic compounds promoted highest...
Climate change can significantly affect and influence, both positively negatively, the wine sector. In this context, adoption of timely, cost-effective adaptation strategies may contribute to reduce such risks, maximise opportunities, enhancing sector's resilience changing climatic conditions. services involve production use climate information support decision-makers adapting variability change. Assessing value benefits using constitutes a critical area research help service providers...
Abstract Recently, the electrospinning technique has been explored as a natural and synthetic polymer processing tool due to its versatility potential generate complex structures at nanoscale. In this work, non-woven nanofibrous mats were electrospun, with structure resembling extracellular matrix, for prospective biomedical uses. Poly (vinyl alcohol) (PVA) cellulose acetate (CA) based electrospun meshes prepared different ratios 100/0, 90/10, 80/20 70/30 characterized in terms of fiber...
The aim of this study was to undergo a comprehensive analysis the thermo-mechanical properties nasal cartilages for future design composite polymeric material be used in human nose reconstruction surgery. A thermal and dynamic mechanical (DMA) tension compression modes within ranges 1 20 Hz 30 °C 250 performed on cartilage. Differential scanning calorimetry (DSC), as well characterization septum (NS), upper lateral (ULC), lower (LLC) reveals different nature binding water inside studied...
Abstract Wet-spinning is a non-solvent induced phase inversion technique that allows the production of continuous polymeric microfibers, with uniform morphology, based on principle precipitation. It 3D fibrous constructs an intricated architecture facilitates cell infiltration, something very limited in electrospun nanofibrous mats, thus increasing its interest biomedicine. Wet-spun scaffolds are also more easily processed and can be loaded variety biomolecules interest. Antimicrobial agents...