A5011933963- Antimicrobial agents and applications
- Antimicrobial Peptides and Activities
- Wound Healing and Treatments
- Essential Oils and Antimicrobial Activity
- Nanocomposite Films for Food Packaging
- Silk-based biomaterials and applications
- Electrospun Nanofibers in Biomedical Applications
- biodegradable polymer synthesis and properties
- Protein Hydrolysis and Bioactive Peptides
- Bee Products Chemical Analysis
- Probiotics and Fermented Foods
- Seed and Plant Biochemistry
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and biological activity
- Cynara cardunculus studies
- Advances in Cucurbitaceae Research
- Periodontal Regeneration and Treatments
- Surgical Sutures and Adhesives
- Advanced Drug Delivery Systems
- Biopolymer Synthesis and Applications
- Advanced Polymer Synthesis and Characterization
- Natural Fiber Reinforced Composites
- Advanced Cellulose Research Studies
- Ionic liquids properties and applications
- Pickering emulsions and particle stabilization
University of Minho
2019-2025
CeNTI (Portugal)
2020-2021
The increased resistance of bacteria against conventional pharmaceutical solutions, the antibiotics, has raised serious health concerns. This stimulated interest in development bio-based therapeutics with limited resistance, namely, essential oils (EOs) or antimicrobial peptides (AMPs). study envisaged evaluation efficacy selected biomolecules, namely LL37, pexiganan, tea tree oil (TTO), cinnamon leaf (CLO) and niaouli (NO), four commonly associated to nosocomial infections: Staphylococcus...
Chronic wounds (CW) create numerous entryways for pathogen invasion and prosperity, further damaging host tissue hindering its remodeling repair. Essential oils (EOs) exert quick efficient antimicrobial (AM) action, unlikely to induce bacterial resistance. Cinnamon leaf clove (CLO CO) display strong AM activity, namely against Staphylococcus aureus Pseudomonas aeruginosa. Chitosan (CS) is a natural biodegradable cationic polysaccharide, also widely known features. CS poly (vinyl alcohol)...
This research aims to explore the potential benefits of natural deep eutectic solvents (NADES) in formulating translucent NADES-in-oil emulsions (TEs) containing essential oils (EOs) for cosmetic applications. The TEs investigated this study are based on previous formulations, consisting 50 wt.% egg phosphatidylcholine (EPC), 20 ethanol, olive oil (OlO), thyme (TO), or oregano (OrO), and 10 NADES made from a 1:1 1:4 ratio lactic acid glycerol (LA). These exhibit high antioxidant activity,...
ABSTRACT Poly(vinyl alcohol)/cellulose acetate (PVA/CA) films were prepared via a new method that combines principles from solvent casting and phase inversion. To guarantee some degree of flexibility, produced with higher percentage PVA compared to CA, 90/10 50/50. The antimicrobial peptide (AMP) LL37 was then anchored using dopamine as binding agent. Films characterized in terms functional groups, thermal stability, tensile strength, porosity, swelling, degradation (stability physiological...
Nisin Z, an amphipathic peptide, with a significant antibacterial activity against Gram-positive bacteria and low toxicity in humans, has been studied for food preservation applications. Thus far, very little research done to explore its potential biomedicine. Here, we report the modification of sodium alginate (SA) gelatin (GN) blended microfibers, produced via wet-spinning technique, purpose eradicating Staphylococcus aureus-induced infections. Wet-spun SAGN microfibers were successfully...
Microbial colonization and development of infections in wounds is a sign chronicity. The prevailing approach to manage treat these involves dressings. However, often fail effectively addressing infections, as they struggle both absorb exudates maintain optimal local moisture. system here presented was conceptualized with three-layer design: the outer layer made fibrous polycaprolactone (PCL) film, act barrier for preventing microorganisms impurities from reaching wound; intermediate formed...
Burn wounds can lead to numerous severe complications including bacterial infections causing patient morbidity and mortality, mostly in low- middle-income countries. The considerable increase microbial resistance against traditional antibiotics is leading towards alternative strategies treat infections. Nisin Z an antimicrobial peptide which exhibits a significant antibacterial activity Gram-positive bacteria. Its efficacy Gram-negative bacteria limited, nonetheless it be improved with the...
Wound care is a growing industry that lately has been facing multiple challenges due to the increasing health costs, aging of population, appearance antibiotic-resistant pathogens, and rise in incidence chronic diseases. Unlike acute wounds which heal predictable amount time following stages healing, (CW) often fail progress past inflammatory phase, costs healing time. Bioactive dressings incorporate drugs/antibiotics or bioactive molecules their formulation have suggested as alternatives...
The incidence of chronic wounds (CW) is growing at an accelerated rate around the world. CW are characterized for failing to progress through orderly phases healing process, stalling inflammatory stage. This disorder often triggered by infections. To address this problem, wound dressings with a nano-architecture and functionalized active biomolecules being engineered. introduction antimicrobial peptides (AMPs), as pexiganan (or MSI-78), which display broad spectrum antibacterial activity...
Chronic wounds (CW) have numerous entry ways for pathogen invasion and prosperity, damaging host tissue hindering remodelling. Essential oils (EOs) exert quick efficient antimicrobial (AM) action, unlikely to induce bacterial resistance. Cajeput oil (CJO) has strong AM properties, namely against Staphylococcus aureus Pseudomonas aeruginosa, as previously established by the team (DOI: 10.3390/antibiotics9060314). Chitosan (CS) is a natural biodegradable cationic polysaccharide, widely known...
The increased resistance of bacteria against conventional pharmaceutical solutions, the antibiotics, has raised serious health concerns. This stimulated interest in development bio-based therapeutics with limited resistance, namely, essential oils (EOs) or antimicrobial peptides (AMPs). study envisaged evaluation efficacy selected biomolecules, namely LL37, pexiganan, tea tree oil (TTO), cinnamon leaf (CLO) and niaouli (NO), four commonly associated to nosocomial infections: Staphylococcus...
Chronic wounds (CW) have numerous entry ways for pathogen invasion and prosperity, damaging host tissue hindering remodeling. Essential oils exert quick efficient antimicrobial (AM) action, unlikely to induce bacterial resistance. Cajeput oil (CJO) has strong AM properties, namely against Staphylococcus aureus Pseudomonas aeruginosa. Chitosan (CS) is a natural biodegradable cationic polysaccharide, also widely known its features. CS poly(vinyl alcohol) (PVA) films were prepared (ratio 30/70;...
Chronic wounds (CW) have numerous entry ways for pathogen invasion and prosperity, damaging host tissue hindering remodeling. Essential oils (EOs) exert quick efficient antimicrobial (AM) action, unlikely to induce bacterial resistance. Cajeput oil (CJO) has strong AM properties, namely against Staphylococcus aureus Pseudomonas aeruginosa, as previously established by the team. Chitosan (CS) is a natural biodegradable cationic polysaccharide, widely known its features. CS (100-300 kDa; DA of...
The high resistance of bacteria against conventional pharmaceutical solutions, the antibiotics, has raised serious global public-health concerns. This stimulated interest in research bio-based therapeutics with limited resistance, namely, antimicrobial peptides (AMPs) or essential oils (EOs). study envisaged evaluation efficacy selected biomolecules, namely LL37, pexiganan, tea tree oil (TTO), cinnamon leaf (CLO) and niaouli (NO), four commonly associated to nosocomial infections:...