A5103224636- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Colorectal Cancer Treatments and Studies
- Cancer Immunotherapy and Biomarkers
- Hepatitis B Virus Studies
- Ferroptosis and cancer prognosis
- Genetic factors in colorectal cancer
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cancer-related molecular mechanisms research
- Asthma and respiratory diseases
- Cancer Genomics and Diagnostics
- Cardiovascular Disease and Adiposity
- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Congenital Diaphragmatic Hernia Studies
- Cancer, Lipids, and Metabolism
- Cardiac Imaging and Diagnostics
- interferon and immune responses
- Non-Invasive Vital Sign Monitoring
- Gastric Cancer Management and Outcomes
- IL-33, ST2, and ILC Pathways
- MicroRNA in disease regulation
- Allergic Rhinitis and Sensitization
- Gallbladder and Bile Duct Disorders
The University of Texas Southwestern Medical Center
2021-2025
Southwestern Medical Center
2021-2025
Imperial College London
2017-2021
Stanley Medical College
2018
552 Background: HIMALAYA showed that D+T and D are effective options for unresectable hepatocellular carcinoma (uHCC). However, data on outcomes according to the adherence inclusion criteria in routine clinical practice lacking. Methods: In context of a prospectively maintained database including 1293 patients (pts) with uHCC treated immunotherapy, we analysed pts or across 8 centres USA, Asia Europe. Pts who met >1 key exclusion criterion (prior systemic therapy, Child-Pugh class B-C,...
INTRODUCTION: Indeterminate liver nodules (ILNs) are frequently encountered on diagnostic imaging after positive hepatocellular carcinoma (HCC) surveillance results, but their natural history remains unclear. METHODS: We conducted a multicenter retrospective cohort study among patients with ≥1 newly detected LI-RADS 3 (LR-3) lesion cm or 4 (LR-4) of any size (per v2018) between January 2018 and December 2019. Patients were followed repeat at each site per institutional standard care....
Abstract Background Incidental gallbladder cancer is relatively rare, with an incidence ranging between 0.19 and 5.5% of all the cholecystectomies for benign disease, carries a poor prognosis. Currently, in literature, there appears to be some controversy about whether specimens should sent routine histopathology. The aim this study was investigate need either or selective histopathological evaluation following cholecystectomy our institution. Methods records patients who underwent...
501 Background: HIMALAYA trial showed that durvalumab plus tremelimumab (Single Tremelimumab Regular Interval Durvalumab; STRIDE) significantly improved overall survival (OS) and (DUR) was non-inferior compared to sorafenib in patients with hepatocellular carcinoma (HCC). However, real world outcomes on this regimen have not been described. Methods: In the context of a prospectively maintained database including 953 (pts) unresectable HCC treated immunotherapy, we analysed subgroup pts...
One of the important aspect in dealing with coronary artery disease (CAD) is ability to identify individuals early stage CAD, before development any adverse clinical event, chronic disability or death. The Epicardial Adipose Tissue Thickness (EATT) and Carotid Intima Media (CIMT) predict presence severity CAD. To try establish a reliable cut-off for detecting disease. It single centre, retrospective case-control study. 244 patients who underwent angiogram were enrolled Echocardiographic...
Background & Aims: Locoregional therapies, including transarterial chemoembolization (TACE), are recommended for the treatment of HCC; however, clinical trials evaluating their effectiveness have been complicated by a lack validated surrogate outcomes. We aimed to evaluate if stage migration could serve as potential overall survival in patients undergoing TACE. Approach: conducted retrospective cohort study adult with HCC who underwent TACE initial therapy from 3 centers US 2008 2019....
Hiatal hernia is frequently encountered by gastroenterologists, typically as an incidental finding. Associated gastroesophageal reflux disease may be managed with proton pump inhibitor therapy, although resistant cases require fundoplication repair of the hernia. We present unusual case a patient paraesophageal hiatal presenting recurrent NSTEMI and cardiac tamponade secondary to extrinsic compression Following comprehensive clinical radiologic evaluation, she underwent nasogastric tube...