Autonomic dysfunction, including baroreceptor attenuation and sympathetic activation, has been reported in patients with myocardial infarction (MI) associated increased mortality. We tested the hypotheses that exercise training (ET) post-MI would normalize arterial baroreflex sensitivity (BRS) muscle nerve activity (MSNA), long-term ET maintain benefits BRS MSNA. Twenty-eight after 1 month of uncomplicated MI were randomly assigned to 2 groups, (MI-ET) untrained. A normal control group was...

Background Brazil is the world's largest producer of sugarcane. Harvest predominantly manual, exposing workers to health risks: intense physical exertion, heat, pollutants from sugarcane burning. Design Panel study evaluate effects burnt harvesting on blood markers and cardiovascular system. Methods Twenty-eight healthy male workers, living in countryside were submitted markers, pressure, heart rate variability, cardiopulmonary exercise testing, sympathetic nerve activity evaluation forearm...

Summary: Purpose : To analyze the effect of prolonged (daily) electrical vagus nerve stimulation (VNS) on daily amygdaloid kindling (AK) in freely moving cats. Methods Fifteen adult male cats were implanted both temporal lobe amygdalae, lateral geniculate bodies, and prefrontal cortices. A bipolar hook (5‐mm separation) stainless steel electrode also was unsectioned left nerve. AK only performed five as a control. The remaining 10 recorded under following experimental conditions: VNS...

We described recently that systemic hypoxia provokes vasoconstriction in heart failure (HF) patients. hypothesized either the exaggerated muscle sympathetic nerve activity and/or endothelial dysfunction mediate blunted vasodilatation during HF Twenty-seven patients and 23 age-matched controls were studied. Muscle was assessed by microneurography forearm blood flow (FBF) venous occlusion plethysmography. Peripheral chemoreflex control evaluated through inhaling of a hypoxic gas mixture (10%...

A detecção de talentos é um processo dinâmico onde o conhecimento científico e dos treinadores devem interagir. O objetivo do estudo foi criar modelo matemático avaliação potencial esportivo para judô testar as suas propriedades psicométricas. Participaram 3426 escolares ambos os sexos 11 a 17 anos colégio militar. Os alunos realizaram uma bateria testes multidimensional, contendo indicadores antropométricos, físico-motores, psicológicos, sociológicos, maturacionais desempenho. 10...

The attenuation of heart rate recovery after maximal exercise (ΔHRR) is independently impaired by obstructive sleep apnea (OSA) and metabolic syndrome (MetS). Therefore, we tested the hypotheses: (1) MetS + OSA restrains ΔHRR; (2) Sympathetic hyperactivation involved in this impairment. Cross-sectional study. We studied 60 outpatients whom had been newly diagnosed (ATP III), divided according to apnea-hypopnea index (AHI) ≥ 15 events/h (n = 30, 49 ± 1.7 y) AHI < - 46 1.4 y). Normal...

New Findings What is the central question of this study? Water drinking increases muscle sympathetic nerve activity (MSNA), and it arterial blood pressure (ABP) in older populations but not young healthy subjects. Does an increase gain baroreflex control MSNA contribute to maintenance ABP after water subjects? main finding its importance? The was increased remained elevated 60 min (500 ml) unchanged saline intake. An enhancement contributes subjects, probably via osmosensitive mechanisms....

The increased morbidity and mortality in traumatic lower limb amputees can be explained by the development of risk factors, among which high blood pressure plays an important role. However, possible mechanisms underlying levels observed this population remain unclear. Thus, we aimed to test hypothesis that peripheral vascular resistance is at rest patients with amputation.In a cross-sectional study, eight unilateral amputation (amputee group) healthy individuals without (control were...

Previous studies have shown that both sympathetic hyperactivity and enhanced inflammatory responses are associated with poor outcomes in patients acute coronary syndrome (ACS). Whether there is a correlation between these two characteristics remains unclear. Thirty-four uncomplicated ACS were evaluated; their mean age was 51.7±7.0 years, 79.4% male, 94.1% had myocardial infarction (MI). On the fourth day of hospitalization, they underwent muscle nerve activity (MSNA) analysis...

Incidence of cardiovascular events follows a circadian rhythm with peak occurrence during morning. Disturbance autonomic control caused by exercise had raised the question safety in morning and its recovery. Furthermore, we sought to investigate whether light aerobic performed at night would increase HR decrease HRV sleep. Therefore, aim this study was test hypothesis that delay recovery after exercise, additionally, tested impact late on sleep sedentary subjects. Nine healthy men (age 24 ±...

Objective The aim of the study was to compare quality life (QOL) patients undergoing hematopoietic stem cell transplantation who improved their functional capacity during hospitalization (increased group) with that maintained or decreased (decreased group). Design This observational, longitudinal included 27 hospitalized transplantation. Patients were divided into increased group (16 patients) and (11 patients). Functional (6-min step test), peripheral muscle strength (sit-to-stand test...

RESUMO A disfunção do sistema nervoso autônomo tem papel importante na fisiopatologia de diversas doenças. Uma possível maneira melhorar o controle autonômico é treinamento muscular inspiratório (TMI), sendo objetivo deste estudo revisar sistematicamente a literatura disponível sobre os efeitos desta modalidade. Dois revisores buscaram ensaios clínicos controlados e randomizados nas bases dados MEDLINE, PEDro, SciELO LILACS, avaliando também sua qualidade metodológica (escala PEDro). Foram...

Background: A family history of hypertension is associated with vascular and autonomic abnormalities, as well an impaired neurohemodynamic response to exercise. Objective: To test the hypothesis that normotensive individuals a present peripheral resistance Methods: The study included 37 volunteers both sexes who were sedentary, eutrophic, nonsmokers, comprising 23 (FH+; 24 ± 3 years) 14 without (FH-; 27 5 hypertension. Blood pressure, heart rate (DIXTAL®), forearm blood flow (Hokanson®),...

Abstract Offspring of hypertensive parents present autonomic dysfunction at rest and during physiological maneuvers. However, the cardiac modulation exercise remains unknown. This study tested whether would be reduced in offspring exercise. Fourteen 14 normotensive individuals were evaluated. The groups matched by age (24.5±1.0 vs. 26.6±1.5 years; p=0.25) BMI (22.8±0.6 24.2±1.0 kg/m2; p=0.30). Blood pressure heart rate assessed simultaneously 3 min baseline followed 3-min isometric handgrip...

Individuals with a family history of systemic arterial hypertension (FHSAH) and / or prehypertension have higher risk developing this pathology.To evaluate the autonomic vascular functions prehypertensive patients FHSAH.Twenty-five young volunteers FHSAH, 14 normotensive 11 subjects were submitted to function evaluation by forearm conductance(VC) during resting reactive hyperemia (Hokanson®) cardiac peripheral modulation, quantified, respectively, spectral analysis heart rate (ECG) systolic...

Gln27Glu (rs1042714) polymorphism of the β2-adrenergic receptor (ADRB2) has been association with cardiovascular functionality in healthy subjects. However, it is unknown whether presence ADRB2 influences neurovascular responses during exercise patients acute coronary syndromes (ACS). We tested hypothesis that ACS homozygous for Gln allele would have increased muscle sympathetic nerve activity (MSNA) and decreased forearm vascular conductance (FVC) compared carrying Glu (Gln27Glu Glu27Glu)....

Aim: This study tested the hypothesis that: 1- exercise training would improve heart rate recovery (HRR) decline after maximal test in hypertensive patients and; 2- normalize HRR when compared to normotensive individuals. Methods: Sixteen were consecutively allocated into two groups: Exercise-trained (n = 9, 47±2 years) and untrained 7, 42±3 years). An exercise-trained group 11, 41±2 was also studied. Heart evaluated by electrocardiogram. The autonomic function based on changes first second...

Aim: The hypothesis that higher levels of anxiety promote greater blood pressure (BP) responses during physical exercise is tested. metaborreflex response increased in an anxious individual tested as well. Methods: There were 43 volunteers divided by level: 12 with mild, moderate and severe symptoms (anxious-group) 31 a minimum level (control-group). Arterial BP, heart rate, forearm flow measured simultaneously handgrip post-exercise ischemia, vascular resistance (FVR) was calculated....