Bruno M. Silva

ORCID: 0000-0003-0473-3706
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About
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Research Areas
  • Cardiovascular and exercise physiology
  • Heart Rate Variability and Autonomic Control
  • Cardiac Arrest and Resuscitation
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Blood Pressure and Hypertension Studies
  • Neuroscience of respiration and sleep
  • Cardiac Ischemia and Reperfusion
  • Cardiovascular Health and Disease Prevention
  • High Altitude and Hypoxia
  • Sports Performance and Training
  • Cardiovascular Effects of Exercise
  • Cardiac Health and Mental Health
  • Cardiovascular Syncope and Autonomic Disorders
  • Non-Invasive Vital Sign Monitoring
  • Adipose Tissue and Metabolism
  • Cardiac Imaging and Diagnostics
  • Infective Endocarditis Diagnosis and Management
  • Genetics and Physical Performance
  • Sodium Intake and Health
  • Angiogenesis and VEGF in Cancer
  • Mobile Ad Hoc Networks
  • Opportunistic and Delay-Tolerant Networks
  • Thermoregulation and physiological responses
  • Cardiac Valve Diseases and Treatments
  • Hemodynamic Monitoring and Therapy

Universidade Federal de São Paulo
2016-2025

Hospital Dr. Nélio Mendonça
2019-2024

Fundação de Apoio à Universidade Federal de São Paulo
2019-2024

Fundação Oswaldo Cruz
2023

Universidade Federal de Minas Gerais
2023

TCL (China)
2022

Olympic Medical Center
2017-2020

Brazilian Medical Association
2016-2017

Universidade de Brasília
2017

Universidade Federal de Goiás
2015

Ischemic preconditioning ( IPC ) of one or two limbs improves performance exercise that recruits the same limb(s). However, it is unclear whether application to another limb than in also effective and which mechanisms are involved. We investigated effect remote RIPC on muscle fatigue, time task failure, forearm hemodynamics, deoxygenation during handgrip exercise. Thirteen men underwent lower a control intervention CON ), random order, then performed constant load rhythmic protocol until...

10.1111/sms.12229 article EN Scandinavian Journal of Medicine and Science in Sports 2014-04-15

Purpose Ischemic preconditioning (IPC) has been shown to improve performance of exercises lasting 10–90 s (anaerobic) and more than 90 (aerobic). However, its effect on repeated sprint controversial, placebo not adequately controlled, nocebo avoided. Thus, the IPC was investigated using a swimming task controlling placebo/nocebo effects. Methods Short-distance university swimmers were randomized two groups. One group (n = 15, 24 ± 1 yr [mean SEM]) exposed (ischemia cycles lasted 5 min)...

10.1249/mss.0000000000000977 article EN Medicine & Science in Sports & Exercise 2016-05-17

Purpose Recent studies have reported ischemic preconditioning (IPC) can acutely improve endurance exercise performance in athletes. However, placebo and nocebo effects not been sufficiently controlled, the effect on aerobic metabolism parameters that determine (e.g., oxygen cost of running, lactate threshold, maximal uptake [V˙O2max]) has equivocal. Thus, we circumvented limitations from previous to test IPC well-trained runners. Methods Eighteen runners (14 men/4 women) were submitted three...

10.1249/mss.0000000000001088 article EN Medicine & Science in Sports & Exercise 2016-08-30

Being overweight or obese is associated with a higher rate of survival in patients advanced chronic obstructive pulmonary disease (COPD). This paradoxical relationship indicates that the influence nutritional status on functional parameters should be further investigated.To investigate impact body composition, exercise capacity and respiratory muscle strength severe patients.Thirty-two (nine women) were divided into three groups according to their mass indices (BMI): overweight/obese (25 < =...

10.1590/s1807-59322010000600007 article EN cc-by-nc Clinics 2010-06-01

The purpose of this article was to determine the individual visual perception thresholds certain facial and dental discrepancies for a symmetric face model (SFM). A photograph female subject's smile digitally manipulated into an artificially picture. Modifications were made on SFM shifts in midline, nose, chin (group 1) cants midline incisal plane 2), resulting total 24 different images divided two groups. One-hundred randomly selected laypersons groups used evaluate each image according...

10.11607/prd.1618 article EN The International Journal of Periodontics & Restorative Dentistry 2013-10-24

Sleep and exercise have an important role in the development of several inflammation-related diseases, including sarcopenia. Objective: To investigate effects 12 weeks resistance training on sleep inflammatory status sarcopenic patients. Methods: A randomized controlled trial comparing (RET) with a control (CTL) was conducted. Outcomes were obtained by physical tests, polysomnography, questionnaires, isokinetic/isometric dynamometry biochemical analysis. Results: Time to onset (sleep...

10.3390/ijerph192316322 article EN International Journal of Environmental Research and Public Health 2022-12-06

Males and females differ anatomically functionally in cardiorespiratory regulation, with males tending to experience greater oxygen desaturation under hypoxia. Therefore, sex might moderate responses acute hypoxia exposure. Accordingly, we hypothesized that differences cardiovascular ventilatory would be more pronounced equal duration (iso-time) but less at similar levels (iso-saturation). Twenty-two (12 females) healthy individuals were exposed normoxia (10 min FiO2 = 0.21) 0.115),...

10.3389/fcvm.2025.1473910 article EN cc-by Frontiers in Cardiovascular Medicine 2025-01-31

<title>Abstract</title> <bold>Purpose</bold> Investigate the prevalence, subtypes (initial, delayed recovery, classic), and hemodynamic mechanisms of orthostatic hypotension in patients with pulmonary arterial hypertension or chronic thromboembolic hypertension.<bold>Methods</bold> Orthostatic was assessed using a 10-min active standing maneuver from supine baseline, heart rate (HR; electrocardiogram) pressure (volume clamp finger photoplethysmography) measured beat-by-beat. Stroke volume...

10.21203/rs.3.rs-6404070/v1 preprint EN Research Square (Research Square) 2025-04-17

ABSTRACT Purpose Some evidence suggests that sedentary women may be more vulnerable to cognitive task-induced mental fatigue. Mental fatigue, in turn, worse aerobic exercise performance, presumably via increased perceived effort. However, it remains unclear whether acute fatigue induction increases effort and worsens endurance performance high-level professional athletes such effects are influenced by sex. Methods We studied 30 (15 16 men) a single-blinded, randomized, controlled crossover...

10.1249/mss.0000000000002346 article EN Medicine & Science in Sports & Exercise 2020-04-03

Abstract The Asian bush mosquito Aedes japonicus is rapidly invading North America and Europe. Due to its potential transmit multiple pathogenic arthropod–borne (arbo)viruses including Zika virus, West Nile chikungunya it important understand the biology of this vector in more detail. In addition arboviruses, mosquitoes can also carry insect-specific viruses that are receiving increasing attention due their effects on host physiology arbovirus transmission. study, we characterized collection...

10.1093/ve/vead041 article EN cc-by Virus Evolution 2023-06-30

Abstract Exercise augments the hypoxia‐induced ventilatory response in an exercise intensity‐dependent manner. A mutual influence of peripheral chemoreflex activation and exercise‐induced muscle metaboreflex might mediate augmentation phenomenon. However, nature these reflexes' integration (i.e., hyperadditive, additive or hypoadditive) remains unclear, coactivation effect on breathing‐related sensations emotions has not been explored. Accordingly, we investigated variables during exercise....

10.1113/ep091094 article EN cc-by Experimental Physiology 2023-04-10

This study’s integrative physiology approach provides evidence for a specific alteration in locomotor muscle metaboreflex control of ventilation patients with COPD. Furthermore, molecular analyses skeletal biopsy suggest that the amount metaboreceptor stimuli derived from type II myocytes and redox imbalance overcame downregulation metabolically sensitive afferents.

10.1152/japplphysiol.00560.2023 article EN Journal of Applied Physiology 2024-01-04

As análises da concentração sanguínea de lactato e das trocas gasosas respiratórias são métodos tradicionalmente empregados para identificar a transição produção energia pelo metabolismo muscular. No entanto, mais recentemente, vem sendo sugerido método alternativo mediante análise variabilidade freqüência cardíaca. Pretendeu-se, com o presente estudo, estabelecer comparações entre limiar cardíaca (LiVFC) primeiro ventilatório (LV1), em uma amostra adolescentes. Para tanto, foram submetidos...

10.1590/s1517-86922005000100003 article PT Revista Brasileira de Medicina do Esporte 2005-02-01

Mental stress induces transient endothelial dysfunction, which is an important finding for subjects at cardiometabolic risk. Thus, we tested whether aerobic exercise prevents this dysfunction among with metabolic syndrome (MetS) and increase in shear rate during plays a role phenomenon. Subjects MetS participated two protocols. In protocol 1 (n = 16), function was assessed using brachial artery flow-mediated dilation (FMD). then underwent mental test followed by either 40 min of leg cycling...

10.1152/ajpheart.00811.2013 article EN AJP Heart and Circulatory Physiology 2014-02-15

Summary Introduction Inconsistent evidences of the metabolic syndrome (MetS) impact on vascular reactivity raise questions flow‐mediated dilation ( FMD ) discriminatory power for disturbances induced by this clustering risk factors. Previous reports, however, suggest that covariates such as follow‐up artery diameter changes, arterial size and shear stress affect responses consequently its distinctive clinical profiles. Objective To determine M et S traditional, size‐ shear‐rate‐adjusted ,...

10.1111/cpf.12092 article EN Clinical Physiology and Functional Imaging 2013-10-10

Physical exercise potentiates the carotid chemoreflex control of ventilation (VE). Hyperadditive neural interactions may partially mediate potentiation. However, some remain incompletely explored. As potentiation occurs even during low-intensity exercise, we tested hypothesis that and muscle mechanoreflex could interact in a hyperadditive fashion. Fourteen young healthy subjects inhaled randomly, separate visits, 12% O2 to stimulate 21% as control. A rebreathing circuit maintained isocapnia....

10.1152/japplphysiol.00009.2018 article EN Journal of Applied Physiology 2018-03-22

Endothelial dysfunction caused by defective nitric oxide (NO) signaling plays a pivotal role in the pathogenesis of intermittent claudication (IC). In present study, we evaluated acute effects sildenafil, phosphodiesterase type 5 inhibitor that acts prolonging NO-mediated cGMP vascular smooth muscle, on blood pressure (BP), skeletal muscle oxygenation, and walking tolerance patients with IC. A randomized, double-blind, crossover study was conducted which 12 men stable IC received two...

10.1152/ajpregu.00183.2014 article EN AJP Regulatory Integrative and Comparative Physiology 2014-06-19
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