A5051607904- Sleep and related disorders
- Sleep and Wakefulness Research
- Obstructive Sleep Apnea Research
- Nutrition and Health in Aging
- Restless Legs Syndrome Research
- Dementia and Cognitive Impairment Research
- Obesity, Physical Activity, Diet
- Chronic Disease Management Strategies
- Diet and metabolism studies
- Clinical Reasoning and Diagnostic Skills
- Health disparities and outcomes
- Neuroscience of respiration and sleep
- Nutritional Studies and Diet
- Aging, Elder Care, and Social Issues
- Attention Deficit Hyperactivity Disorder
- Frailty in Older Adults
- Sleep and Work-Related Fatigue
- Muscle metabolism and nutrition
- Neuroscience and Neuropharmacology Research
- Innovations in Medical Education
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Circadian rhythm and melatonin
- Global Maternal and Child Health
- Epilepsy research and treatment
- Patient Safety and Medication Errors
Universidade Federal de São Paulo
2014-2025
The University of Adelaide
2021-2025
Women's and Children's Health Network
2025
Central Adelaide Local Health Network
2021-2024
Queen Elizabeth Hospital
2021-2024
Associação Fundo de Incentivo à Pesquisa
2021
Federal Institute of São Paulo
2020
Instituto do Sono
2019
The fear and uncertainty caused by the coronavirus disease 2019 (COVID-19) pandemic, threats to survival are one of main problems everyday life; however, mental health care must also be considered a priority. During social isolation called self-quarantine, restricted mobility contact, concern about financial resources availability supplies, infection, questions duration cause anxiety, depression, stress, insomnia reduced quality quantity sleep, that may present greater risk general...
While efforts have been made to validate intrinsic capacity (IC) as a multidimensional indicator of healthy aging in high-income countries, we still need evidence from lower-income countries. We examined associations IC with wide ranges activities daily living nationally representative sample Brazilians aged≥50 years.This cross-sectional analysis included 7175 participants the Brazilian Longitudinal Study Aging. domains (cognitive, psychological, sensory, locomotor, and vitality) were...
Objective To evaluate the association between objective short sleep duration in patients with insomnia and changes blood parameters related to hypothalamic-pituitary-adrenal (HPA) axis activity.Method A cross-sectional pilot study was conducted 30 middle-aged adults chronic who were divided into 2 groups according polysomnography (PSG) total time (TST) (TST > 5h < 5h). All underwent subjective analysis of quality, anthropometric measurements, PSG, determination off asting...
Background Studies demonstrate an association between vitamin D (25(OH)D) deficiency and sleep disturbances, such as obstructive apnea (OSA) short duration. However, to date, no studies have concurrently objectively evaluated the effect of these factors on 25(OH)D. Objectives To evaluate whether OSA objective duration are independently associated with reduced 25(OH)D in adult population sample. Methods A cross-sectional study included 657 individuals from city Sao Paulo, Brazil, part ERA...
Abstract Background Evidence suggests anthropometric indicators of obesity are associated with changes in sleep quality and quantity, the presence obstructive apnoea (OSA). Investigations including diverse objective evaluations body composition scarce. We aimed to evaluate associations between impairment states a sample from population‐based study. Methods Participants first follow‐up EPISONO (São Paulo, Brazil) > 50 years were cross‐sectionally evaluated. Sleep was assessed through...
Since the beginning of COVID-19 pandemic, older adults have been found to be a highly vulnerable group, with higher prevalence severe cases and negative outcomes. Research has focused on reasons why are at greater risk; Sleep-related factors suggested as one possible explanation for this. An individual’s sleep pattern undergoes significant changes over course their life. In specific profile can observed, characterized by advanced timing, morningness preference, longer sleep-onset latency,...
Sleep and exercise have an important role in the development of several inflammation-related diseases, including sarcopenia. Objective: To investigate effects 12 weeks resistance training on sleep inflammatory status sarcopenic patients. Methods: A randomized controlled trial comparing (RET) with a control (CTL) was conducted. Outcomes were obtained by physical tests, polysomnography, questionnaires, isokinetic/isometric dynamometry biochemical analysis. Results: Time to onset (sleep...
Muscle mass is associated with physical and functional performance across adulthood. Its reduction plays a crucial role in the development of age-related conditions such as frailty sarcopenia. Genetic variations potentially impact muscle health, particularly an aged population. For this reason, we aimed to evaluate association between genetic biomarkers appendicular lean index (ALMI), marker identify possible risk factors for sarcopenia population-based study. We cross-sectionally analyzed...
Summary Although drugs with sedative properties may increase the risk of airway collapse during sleep, their acute effects on apnea–hypopnea index in older adults are under‐reported. We investigated gabapentin ( GABA ) sleep breathing men without apnea. A double‐blind, randomized, placebo‐controlled cross‐over pilot study using a bedtime dose 300 mg was conducted eight non‐obese men. Polysomnography measured intervention. The higher arm than placebo (22.4 ± 6.1 versus 12.2 4.3, P ≤ 0.05, d :...
Background: Dementia is the main cause of disability in older people living low-and middle-income countries (LMIC).Monitoring mortality rates and risk factors with dementia (PwD) may contribute to improving care provision.Objective: We aimed estimate predictors PwD from eight LMICs.Methods: This 3-5-year prospective cohort study involved a sample 1,488 LMIC.Total, age-and gender-specific per 1,000 person-years at risk, as well total, gender-adjusted were estimated for each country's...
Aging is accompanied by changes in the quantity and quality of sleep. Obstructive sleep apnea (OSA) also more prevalent older population. Although severe OSA has been linked to a higher risk cardiovascular disease regardless adult age, clinical consequences mild-to-moderate adults are still uncertain.To investigate relationships between severity metabolic, cognitive, functional characteristics community-dwelling from representative sample city São Paulo.In total, 199 participants first...
A challenging aspect of geriatric practice is that it often requires decision‐making under conditions uncertainty. The S cript C oncordance T est ( SCT ) an assessment tool designed to measure clinical data interpretation, important element reasoning purpose this study was develop and analyze the validity results administered undergraduate students in medicine. An consisting 13 cases 104 items covering a spectrum common problems 41 medical at school ão P aulo, B razil. reference panel 21...
Pharmacist-led medication regimen simplification using a structured approach can reduce unnecessary complexity in residential aged care facilities (RACFs), but no studies have investigated by different health professionals, nor the extent to which is recommended during comprehensive reviews. To compare opportunities identified pharmacists, general medical practitioners (GPs), and geriatricians determine if pharmacists routinely conducted reviews RACFs for these same residents. Three three...
Objective: People with Alzheimer's disease (AD) dementia have impaired sleep. However, the characteristics of sleep in early stages AD are not well known, and studies aid biomarkers lacking. We assessed subjective non-demented older adults compared their amyloid profiles. Methods: enrolled 30 participants aged ≥ 60 years, no or major clinical psychiatric diseases. They underwent [11C]PiB-PET-CT, neuropsychological evaluations, completed two standardized assessments (Pittsburgh Sleep Quality...
A avaliação do raciocínio clínico em situações de incerteza é pouco pesquisada na educação médica. Os testes escritos mais aplicados são múltipla escolha, capazes avaliar como se lida com problemas bem definidos. Porém, a maioria das contém incertezas. Um método contextos foi desenvolvido partir da teoria scripts, geriatria. grupo especialistas e um estudantes graduação resolveram o teste. Acomparação entre os resultados trouxe indícios validade instrumento, capaz diferenciar relacionado ao...