A5047534298- Nutrition and Health in Aging
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Vitamin D Research Studies
- Lipoproteins and Cardiovascular Health
- Health, Nursing, Elderly Care
- Bone health and osteoporosis research
- Nutritional Studies and Diet
- Body Composition Measurement Techniques
- Adipokines, Inflammation, and Metabolic Diseases
- Healthcare Regulation
- Frailty in Older Adults
- Dementia and Cognitive Impairment Research
- Musculoskeletal pain and rehabilitation
- Parathyroid Disorders and Treatments
- Cardiovascular Health and Disease Prevention
- Blood Pressure and Hypertension Studies
- Health disparities and outcomes
- Physical Education and Gymnastics
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Health and Well-being Studies
- Sleep and related disorders
- Diet and metabolism studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Male Reproductive Health Studies
- Balance, Gait, and Falls Prevention
Universidade Federal de São Paulo
2016-2025
Hospital Israelita Albert Einstein
2003-2018
Hospital São Paulo
2018
Universidade de São Paulo
2018
Fundação de Apoio à Universidade Federal de São Paulo
2009-2017
British Geriatrics Society
2013
Tambov State Technical University
2008
Tufts University
1999-2004
INTRODUCTION: Previous cross-sectional studies have shown a high prevalence of chronic disease and disability among the elderly. Given Brazil’s rapid aging process obvious consequences growing number old people with diseases associated disabilities for provision health services, need was felt study that would overcome limitations data shed some light on main factors determining whether person will live longer free disabling diseases, so-called successful aging. The methodology first...
A ocorrência de fraturas osteoporóticas em idosos está relacionada às concentrações reduzidas vitamina D e conseqüente hiperparatiroidismo secundário, sendo os institucionalizados maior risco. No Brasil, por seu alto grau insolação, infere-se que a quantidade da população seja adequada. Neste estudo, objetivamos avaliar as plasmáticas 25-hidroxivitamina (25OHD), paratormônio (PTH) cálcio ionizado (Cai), assim como analisar prevalência hipovitaminose secundário moradores cidade São Paulo....
Abstract Background Equations to estimate GFR have not been well validated in the elderly and may misclassify persons with chronic kidney disease (CKD). We measured compared performance of Modification Diet Renal Disease (MDRD), Chronic Kidney Disease-Epidemiology Collaboration (CKD-Epi) Berlin Initiative Study (BIS) equations based on creatinine and/or cystatin C octogenarians nonagenarians. Methods Using cross-sectional analysis we assessed 95 very (mean 85 years) living community. was by...
Some individuals are able to successfully reach very old ages, reflecting higher adaptation against age-associated effects. Sleep is one of the processes deeply affected by aging; however few studies evaluating sleep in long-lived (aged over 85) have been reported date. The aim this study was characterize patterns and biochemical profile oldest (N=10, age 85-105 years old) compare them young adults (N=15, 20-30 older (N=13, 60-70 old). All subjects underwent full-night polysomnography,...
Objective: To evaluate the 25-hydroxyvitamin D [25(OH)D] concentrations in individuals city of São Paulo belonging to different age groups and exhibiting specific behavioral characteristics correlate 25(OH)D concentration with level UV radiation (UVR). Patients Methods: A total 591 were included, distributed as follows: 177 living institutions (NURSING, 76.2 ± 9.0 y old), 243 part community elderly (COMMUNITY, 79.6 5.3 99 enrolled a physical activity program targeting (ACTIVE, 67.6 5.4 old)...
Hypovitaminosis D is a common condition among elderly individuals in temperate-climate countries, with clear seasonal variation on 25 hydroxyvitamin [(25(OH)D] levels, increasing after summer and decreasing winter, but there are few data from sunny countries such as Brazil. We aimed to evaluate 25-hydroxyvitamin concentrations its determining factors, the city of São Paulo belonging different age groups presenting sun exposure habits. 591 people were included follows: 177 living institutions...
Chronic kidney disease (CKD) leads to reduced bone mineral density (BMD) in pre-dialysis and dialysis patients. A few studies have used dual-energy x-ray absorptiometry (DEXA) assess BMD CKD patients shown low be highly prevalent. Until now there been no reporting the histological features of patients.To determine prevalence patients.Pre-dialysis (n = 103, 46 females/57 males), median creatinine clearance 29 (10 - 78) ml/min/ 1.73 m2, were evaluated using biochemical analysis DEXA. Bone...
The aim of this study was to investigate if there is a relation among 25(OH)D, aquatic training, and multifunctional fitness on functional performance elderly woman from the community.
The loss of cholinergic transmission is considered to be an important cause Alzheimer’s disease (AD). Treatment with acetyl cholinesterase inhibitors (ChEIs) shows benefits; however, great heterogeneity has been observed in patient responses. We evaluated apolipoprotein E ( APOE) and α7 nicotinic receptor CHRNA7) single-nucleotide polymorphisms (SNPs) associated these SNPs pharmacological responses ChEIs a Brazilian population AD. studied 177 outpatients using ChEIs, they were classified as...
SUMMARY: Background: Nitric oxide (NO) released from endothelial cells is related to the maintenance of physiological vascular tone. The impairment NO generation brought about by gene polymorphism considered one deterioration factors in progressive renal disease. In nitric synthase (eNOS) intron 4 polymorphism, presence aa genotype has been associated with cardiovascular and aim this study was investigate eNOS patients end‐stage disease (ESRD). Methods: A total 114 94 controls were studied....
Introduction APOA1/C3/A4/A5 gene cluster is closely involved in lipid metabolism, and its polymorphisms have been associated with coronary heart disease plasma levels. Here, we aimed to investigate associations of APOC3 (3238C>G, −482C>T, 1100C>T) APOA4 (Gln360His, Thr347Ser) 382 individuals from a cohort Longitudinal Brazilian Elderly Study major age-related morbidities protein serum Materials Methods The whole sample was genotyped by polymerase chain reaction-restriction fragment...
SUMMARY Objective To compare the health-related quality of life (HRQL) indicators between institutionalized and community-dwelling elderly men women. Method This was a cross-sectional study with sample 496 women, surveyed by researchers at private hospital that attends elderly. HRQL (World Health Organization Quality Life), daily living activities (Katz questionnaire), instrumental (Lawton mini-mental state examination, handgrip strength test, function capacity (timed up go test) were...
We evaluated the frequency of fatigue in geriatric patients with and without Parkinson's disease (PD) correlated it depression excessive daytime sleepiness. 100 from Hospital São Paulo, 50 PD Neurologic Outpatient Clinic non-neurologic diseases or oncologic Geriatric (controls). All who scored 28 more on Fatigue Severity Scale (FSS) were considered to have fatigue. Also, all submitted a structured interview diagnose by criteria American Psychiatric Association (DSM-IV, 4th version) Modified...
To evaluate and compare the frequency severity of major depression in patients with Parkinson's disease individuals older than 60 years without neurological, rheumatological and/or oncological comorbidities.We studied 50 geriatric patients. Subjects scores Mini Mental State Examination indicating cognitive impairment were excluded. We used Diagnostic Statistical Manual Diseases-IV criteria to diagnose Hamilton Depression Scale Beck Inventory rate it. The Unified Disease Rating part 3 Hoehn...
A challenging aspect of geriatric practice is that it often requires decision‐making under conditions uncertainty. The S cript C oncordance T est ( SCT ) an assessment tool designed to measure clinical data interpretation, important element reasoning purpose this study was develop and analyze the validity results administered undergraduate students in medicine. An consisting 13 cases 104 items covering a spectrum common problems 41 medical at school ão P aulo, B razil. reference panel 21...
BACKGROUND AND OBJECTIVES: Chronic pain considerably worsens quality of life the elderly, giving relevance to studies addressing it in such individuals, especially those long-lived. Recently, vitamin D deficiency, very prevalent among has been correlated chronic pain. This study aimed at estimating prevalence community long-lived elderly with functional independence, evaluating its characteristics and correlating this serum levels. METHODS: Cross-sectional "Long-Lived Project", aged 80 years...
The levels of electronegative low-density lipoprotein (LDL-), LDL cholesterol oxidability, and plasma molecular antioxidants β2-glycoprotein I (β2 GPI) were studied in a group 10 hypercholesterolemic (HC) normocholesterolemic (NC) elderly subjects. HC subjects showed significantly higher cholesterol, LDL-, β2GPI than NC, whereas high-density α-tocopherol lower as compared with NC Correlations among LDL- levels, oxidation lag time, β2GPI, antioxidant 100 Lag time for vitro positively...