A5033893286- Dialysis and Renal Disease Management
- Iron Metabolism and Disorders
- Heart Failure Treatment and Management
- Erythropoietin and Anemia Treatment
- Nutrition and Health in Aging
- Parathyroid Disorders and Treatments
- Chronic Kidney Disease and Diabetes
- Hemoglobinopathies and Related Disorders
- Blood Pressure and Hypertension Studies
- Public Health in Brazil
- Renal function and acid-base balance
- Acute Kidney Injury Research
- Leptospirosis research and findings
- Electrolyte and hormonal disorders
- Liver Disease Diagnosis and Treatment
- Acute Ischemic Stroke Management
- Health Systems, Economic Evaluations, Quality of Life
- Renal Diseases and Glomerulopathies
- Health disparities and outcomes
- Peripheral Artery Disease Management
- Sepsis Diagnosis and Treatment
- Potassium and Related Disorders
- Dermatology and Skin Diseases
- Global Health Care Issues
- Membrane-based Ion Separation Techniques
Arbor Research Collaborative for Health
2019-2024
Universidade Federal da Bahia
2001-2024
Complexo Hospitalar Universitário Professor Edgard Santos
2016-2024
Rafael Advanced Defense Systems (Israel)
2024
Hospital São Rafael
2022-2024
D’Or Institute for Research and Education
2022-2024
Hospital Virgen de la Salud
2015
Universidade Federal de São Paulo
2013
Schlumberger (British Virgin Islands)
2009
Hospital Ana Nery
2004
Abstract Background Equations to estimate GFR have not been well validated in the elderly and may misclassify persons with chronic kidney disease (CKD). We measured compared performance of Modification Diet Renal Disease (MDRD), Chronic Kidney Disease-Epidemiology Collaboration (CKD-Epi) Berlin Initiative Study (BIS) equations based on creatinine and/or cystatin C octogenarians nonagenarians. Methods Using cross-sectional analysis we assessed 95 very (mean 85 years) living community. was by...
Serial assessment of phosphorus is currently recommended by the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines, but its additional value versus a single measurement uncertain.We studied data from 17 414 HD patients in Dialysis and Practice Patterns Study, prospective cohort study, calculated area under curve (AUC) multiplying time spent with serum >4.5 mg/dL over 6-month run-in period extent to which this threshold was exceeded. We estimated association between monthly average...
Background: Chronic kidney disease (CKD) elevates the risk of cardiovascular and overall mortality among maintenance hemodialysis (MHD) patients. Although initially designed to predict stroke in cases atrial fibrillation, CHA2DS2-VASc score demonstrates predictive utility, spanning several conditions. This study seeks evaluate if is effective predicting all-cause for MHD Methods: The data are part "Prospective Study Prognosis Patients on Hemodialysis" (PROHEMO) developed Salvador, BA,...
There is evidence that an early start of penicillin reduces the case-fatality rate leptospirosis and chemoprophylaxis efficacious in persons exposed to sources leptospira. The existent data, however, are inconsistent regarding benefit introducing at a late stage leptospirosis. present study was developed assess whether introduction after more than four days symptoms in-hospital A total 253 patients aged 15 76 years with advanced leptospirosis, i.e., symptoms, admitted infectious disease...
Iron deficiency (ID) is a common condition in nondialysis-dependent chronic kidney disease (NDD-CKD) patients that associated with poorer clinical outcomes. However, the effect of ID on health-related quality life (HRQoL) this population unknown. We analyzed data from multinational cohort NDD-CKD Stages 3-5 to test association between transferrin saturation (TSAT) index and ferritin HRQoL.Patients Brazil (n = 205), France 2015) USA 293) Chronic Kidney Disease Outcomes Practice Patterns Study...
Abstract Previously lacking in the literature, we describe longitudinal patterns of anemia prescriptions for non-dialysis-dependent chronic kidney disease (NDD-CKD) patients under nephrologist care. We analyzed data from 2818 Stage 3-5 NDD-CKD Brazil, Germany, and US, naïve to medications (oral iron, intravenous [IV] or erythropoiesis stimulating agent [ESA]) at enrollment CKDopps. report cumulative incidence function (CIF) medication initiation stratified by baseline characteristics. Even...
Rationale & ObjectiveChronic kidney disease-associated pruritus has been linked with poorer mental and physical health-related quality of life (HR-QOL) in patients receiving hemodialysis. We used the Skindex-10 questionnaire a single itch-related question to evaluate their prediction HR-QOL.Study DesignProspective, international cohort.Setting ParticipantsWe analyzed data from 4,940 hemodialysis 17 countries enrolled phase 5 (2013) Dialysis Outcomes Practice Patterns Study.PredictorsThe...
The identification of malnutrition-inflammation-complex (MIC) and functional status (FS) is key to improving patient experience on hemodialysis (HD). We investigate the association MIC FS combinations with mortality in HD patients. analyzed data from 5630 patients 9 countries DOPPS phases 4-5 (2009-2015) a median follow-up 23 [IQR 11, 31] months. was defined as serum albumin < 3.8 g/dL C-reactive protein > 3 mg/L Japan 10 elsewhere. score sum scores Katz Index Independence Activities Daily...
Abstract Aims Cardiac troponin (cTn) and B‐type natriuretic peptide (BNP) are elevated in haemodialysis (HD) patients, this elevation is associated with HD‐induced myocardial stunning/myocardial strain. However, studies using data from the international Dialysis Outcomes Practice Patterns Study (DOPPS) have shown that these cardiac biomarkers measured <2% of HD patients real‐world practice. This study aimed to examine whether routinely N‐terminal pro‐BNP (NT‐proBNP) cTnI (contemporary...
While high serum phosphorus levels have been related to adverse outcomes in hemodialysis patients, further investigation is warranted persons receiving peritoneal dialysis (PD).Longitudinal data (2014-17) from the Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS), a prospective cohort study, were used examine associations of with all-cause mortality major cardiovascular events via Cox regression adjusted for confounders. Serum parameterized by four methods: (i) baseline...
Some studies on maintenance hemodialysis (MHD) patients report a longer survival, albeit with poorer health-related quality of life (HRQoL), and more depression symptoms in women than men. Whether these gender differences vary age is uncertain. We tested the associations mortality, symptoms, HRQoL MHD different groups.We used data from 1504 adult enrolled PROHEMO, prospective cohort Salvador, Brazil. The KDQOL-SF was for component summaries mental (MCS) physical (PCS) scales. Depression were...
The main objective was to compare the in-hospital case-fatality rate of leptospirosis between pediatric (< 19 years) and adult (>19 patients, taking into account gender, renal function, duration symptoms jaundice. Medical records 1016 patients were reviewed. Comparative analysis restricted 840 (100 pediatric, 740 adults) with recorded information on variables included in analysis. Among these 81.7% male 91.5% icteric. 14.4%. odds death adjusted for jaundice, symptoms, serum urea...
Abstract Social distancing measures have emerged as the predominant intervention for containing spread of COVID-19, but evaluating adherence and effectiveness remains a challenge. We assessed relationship between aggregated mobility data collected from mobile phone users time-dependent reproduction number R(t), using severe acute respiratory illness (SARI) cases reported by São Paulo Rio de Janeiro. found that proportion individuals staying home all day (isolation index) had strong inverse...
Objective: To investigate associations of sex-age-specific handgrip strength by a dynamometer with all-cause mortality and the percent excess risk explained (%ERE) comorbidities nutritional indicators in incident maintenance hemodialysis patients. Methods: Prospective cohort 413 adult patients (165 women, 248 men, 299 <60 years 114 ⩾60 years) <6 months (82% <3 months) on dialysis enrolled PROHEMO Salvador, Brazil. Low high groups were based cutoffs (17.8 kg for women years, 13.8...
Abstract Background Functional dependence is highly prevalent in maintenance hemodialysis (MHD) settings. Also, poor health-related quality of life (HRQoL) and high levels depressive symptoms have been reported by MHD patients. We investigated associations between functional status mental aspects Brazilian Methods Cross sectional study 235 patients enrolled two the four participating clinics Prospective Study Prognosis Chronic Hemodialysis Patients (PROHEMO) Salvador, BA, Brazil. Data were...
Background/objective: A high prevalence of fatigue and a positive association between post-hemodialysis recovery have been reported in predominantly white populations maintenance hemodialysis (MHD) patients. The present study evaluates associations self-reported by the 11-item Chalder Fatigue Questionnaire (CFQ-11) need for African-descent MHD population. Methods: total 233 patients (94% Black or Mixed-Race) participating “Prospective Study Prognosis Patients on Maintenance Hemodialysis”...
To assess the association between sex and left ventricular hypertrophy, stroke, renal failure in hypertensive patients a referral outpatient care unit.This study assessed 622 diagnosed with hypertrophy based on electrocardiography, serum creatinine level > or = 1.4 mg/dL, stroke previous history physical examination. Logistic regression was used to estimate odds ratio of target-organ lesions hypertension adjusted for race, age, duration disease.The mean age 48.4 +/- 13.8 years; 74.1% were...
To assess whether a patient's race is associated with the presence of left ventricular hypertrophy, stroke, and renal failure in hypertensive patients from an outpatient care referral clinic city Salvador state Bahia. We assessed data 622 collected during their first visit to hypertension between 1982 1986, identifying those previous history or sequela (serum creatinine > 1.4 mg/dL). Logistic regression models were used estimate odds ratio (OR) association (mulattos black vs white...
Early diagnosis is essential for the appropriate management of acute kidney injury (AKI). We evaluated impact an electronic AKI alert together with a care bundle on progression and mortality AKI. This was single-center prospective study that included patients aged ≥ 18 years, whereas those in palliative care, nephrology, transplantation departments were excluded. An issued medical records suggested. A series classes administered to multidisciplinary teams by nephrologists, clinical...
This study was designed to estimate the prevalence of pulmonary radiograph abnormalities and describe distribution patterns radiographic alterations among patients hospitalized with leptospirosis. Chest radiographs 139 leptospirosis in Couto Maia Hospital, Salvador, Bahia, Brazil, between July, 1997, 1999, were analyzed. The requested soon after hospital admission, independent clinical manifestations patients. Only first considered. Pulmonary recorded 35/139 (25.2%); 95% mid-point confidence...
OBJETIVO: Avaliar se existe evidência que apóie diferentes intervenções para tratar insuficiência cardíaca baseada na raça ou etnia. MÉTODOS: Revisão sistemática de ensaios clínicos randomizados permitiram comparar negros e brancos com sistólica crônica quanto à eficácia inibidores da enzima conversora angiotensina (ECA), betabloqueadores combinação hidralazina/nitrato redução dos riscos morte hospitalização. A pesquisa foi em artigos publicados entre 1980 dezembro 2006, citados no Medline...
BACKGROUND: In the absence of vaccines and effective pharmacological interventions to reduce with COVID-19 transmission, social distancing measures have been implemented mitigate impact on healthcare systems secure time prepare public health response. METHODS: We assessed relationship between mobility data collected by mobile phone time-dependent reproduction number R(t) using severe acute respiratory illness cases reported 102 Brazilian cities confirmed until April 15, grouped demographic...