A5033857644- Dialysis and Renal Disease Management
- Central Venous Catheters and Hemodialysis
- Renal Diseases and Glomerulopathies
- Health Systems, Economic Evaluations, Quality of Life
- Antifungal resistance and susceptibility
- Chronic Kidney Disease and Diabetes
- Muscle and Compartmental Disorders
- Renal Transplantation Outcomes and Treatments
- Vasculitis and related conditions
- Acute Kidney Injury Research
- Kidney Stones and Urolithiasis Treatments
- Fungal Infections and Studies
- Plant Pathogens and Fungal Diseases
- COVID-19 Clinical Research Studies
- Parasitic Diseases Research and Treatment
- Potassium and Related Disorders
- Nutrition and Health in Aging
- Pharmacological Effects and Toxicity Studies
- SARS-CoV-2 detection and testing
- Healthcare cost, quality, practices
- Therapeutic Uses of Natural Elements
- COVID-19 and healthcare impacts
- Iron Metabolism and Disorders
- Blood Pressure and Hypertension Studies
- Heparin-Induced Thrombocytopenia and Thrombosis
Chulalongkorn University
2016-2025
King Chulalongkorn Memorial Hospital
2015-2025
Pediatric Nephrology of Alabama
2024
Bangkok Hospital
2024
Bangkok Metropolitan Administration
2024
ChiangRai Prachanukroh Hospital
2024
Naresuan University
2024
Thai Red Cross Society
2013-2024
University of Phayao
2024
Charoenkrung Pracharak Hospital
2024
Peritoneal dialysis (PD)-associated peritonitis is a serious complication of PD and prevention treatment such important in reducing patient morbidity mortality. The ISPD 2022 updated recommendations have revised clarified definitions for refractory peritonitis, relapsing peritonitis-associated catheter removal, PD-associated haemodialysis transfer, death hospitalisation. New categories outcomes including pre-PD enteric catheter-related medical cure are defined. new targets recommended...
Increased plasminogen activator inhibitor 1 (PAI-1) has been linked to not only thrombosis and fibrosis but also obesity insulin resistance. PAI-1 levels have presumed be consequent obesity. We investigated the interrelationships of PAI-1, obesity, resistance in a high-fat/high-carbohydrate (HF) diet–induced model wild-type (WT) PAI-1–deficient mice (PAI-1−/−). Obesity developing WT on an HF diet were completely prevented lacking PAI-1. PAI-1−/− had increased resting metabolic rates total...
Rationale & ObjectivePeritoneal dialysis (PD)-related peritonitis carries high morbidity for PD patients. Understanding the characteristics and risk factors can guide regional development of prevention strategies. We describe rates associations selected facility practices with among countries participating in Peritoneal Dialysis Outcomes Practice Patterns Study (PDOPPS).Study DesignObservational prospective cohort study.Setting Participants7,051 adult patients 209 facilities across 7...
Home dialysis modalities (home hemodialysis [HD] and peritoneal [PD]) are associated with greater patient autonomy treatment satisfaction compared in-center modalities, yet the level of home-dialysis use worldwide is low. Reasons for limited utilization context-dependent, informed by local resources, costs, access to healthcare, health system policies, provider bias or preferences, cultural beliefs, individual lifestyle concerns, potential care-partner time, financial burdens. In May 2021,...
Individuals with kidney failure undergoing maintenance dialysis frequently report a high symptom burden that can interfere functioning and diminish life satisfaction. Until recently, the focus of nephrology care for patients has been related primarily to numerical targets laboratory measures, outcomes such as cardiovascular disease mortality. Routine assessment is not universal or standardized in care. Even when symptoms are identified, treatment options limited initiated infrequently, part...
Background. Currently, estimated glomerular filtration rate (eGFR) equations have been validated only in Caucasians and African-Americans is not applicable to people of other races/ethnicities as shown studies conducted two Asian populations: Chinese Japanese. Because this, it important that eGFR are its prospective population before applying the clinical setting epidemiologic studies. Therefore, we examined all available: reexpressed isotope dilution mass spectroscopy (IDMS)-traceable...
Repurposed drugs with host-directed antiviral and immunomodulatory properties have shown promise in the treatment of COVID-19, but few trials studied combinations these agents. The aim this trial was to assess effectiveness affordable, widely available, repurposed used combination for which may be particularly relevant low-resource countries.
Increased plasminogen activator inhibitor-1 (PAI-1) is linked to obesity and insulin resistance. However, the functional role of PAI-1 in adipocytes unknown. This study was designed investigate effects underlying mechanisms on glucose uptake adipocyte differentiation. Using primary cultured from PAI-1(+/+) PAI-1(-/-) mice, we found that deficiency promoted differentiation, enhanced basal insulin-stimulated uptake, protected against tumor necrosis factor-alpha-induced dedifferentiation These...
Peritoneal dialysis (PD)-related infections lead to significant morbidity. The International Society for Dialysis (ISPD) guidelines the prevention and treatment of PD-related are based on variable evidence. We describe practice patterns across facilities participating in Outcomes Practice Patterns Study (PDOPPS).PDOPPS, a prospective cohort study, enrolled nationally representative samples PD patients Australia/New Zealand (ANZ), Canada, Thailand, Japan, UK USA. Data infection practices were...
Introduction The number of patients with CKD has been increasing worldwide. In Thailand, 11.6 million (17.5%) people currently have CKD, 5.7 (8.6%) advanced (stages 3–5), and over 0.1 require dialysis (1). Every year, >20,000 ESKD need treatment hemodialysis (HD) or peritoneal (PD) (2). Since the first HD performed in 1964 PD 1982, Thai treated only gradually increased three decades because limited access arising from prohibitive costs, which precipitated catastrophic health expenditure for...
The monkeypox virus is excreted in the feces of infected individuals. Therefore, there an interest using viral load detection wastewater for sentinel early surveillance at a community level and as complementary approach to syndromic surveillance. We collected from 63 sewered non-sewered locations Bangkok city center between May August 2022. Monkeypox DNA copy numbers were quantified real-time polymerase chain reaction (PCR) confirmed positive by Sanger sequencing. was first detected second...
Quantifying contemporary peritoneal dialysis time on therapy is important for patients and providers. We describe in the context of outcomes hemodialysis transfer, death, kidney transplantation basis multinational, observational Peritoneal Dialysis Outcomes Practice Patterns Study (PDOPPS) from 2014 to 2017.Among 218 randomly selected facilities (7121 patients) PDOPPS Australia/New Zealand, Canada, Japan, Thailand, United Kingdom, States, we calculated cumulative incidence start or over 5...
Discover the shifting landscape of SARS-CoV-2 variants from October to December 2023, with JN.1 dominating South and Southeast Asia wastewater samples, increasing <10% >90%. Experience dynamic evolution viral strains in this period.
Background: We describe peritoneal dialysis (PD) prescription variations among Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS) participants on continuous ambulatory PD (CAPD) automated (APD; n = 4657) from Australia/New Zealand (A/NZ), Canada, Japan, Thailand, United Kingdom (UK), States (US). Results: CAPD was more commonly used in Thailand while APD predominated over A/NZ, the US, UK. Total prescribed volume normalized to surface area highest lowest Japan (for both CAPD)...
As the worst global pandemic of past century, coronavirus disease 2019 (COVID-19) has had a disproportionate effect on maintenance dialysis patients and their health care providers. At virtual roundtable June 12, 2020, Dialysis Outcomes Practice Patterns Study (DOPPS) investigators from 15 countries in Asia, Europe, Americas described compared effects COVID-19 care, with recent updates added. Most striking is huge difference risk to staff across world. Per-population cases deaths among vary...