Ilaria Spalla

ORCID: 0000-0003-0039-1438
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Research Areas
  • Cardiovascular Conditions and Treatments
  • Congenital Heart Disease Studies
  • Cardiac Arrhythmias and Treatments
  • Cardiomyopathy and Myosin Studies
  • Pulmonary Hypertension Research and Treatments
  • Cardiovascular Function and Risk Factors
  • Mechanical Circulatory Support Devices
  • Cardiac pacing and defibrillation studies
  • Cardiovascular Effects of Exercise
  • Cardiovascular Disease and Adiposity
  • Veterinary Medicine and Surgery
  • Cardiac electrophysiology and arrhythmias
  • Congenital heart defects research
  • Vascular anomalies and interventions
  • Respiratory Support and Mechanisms
  • Ultrasound in Clinical Applications
  • Viral Infections and Immunology Research
  • Veterinary Oncology Research
  • Animal Virus Infections Studies
  • Thyroid Disorders and Treatments
  • Wireless Power Transfer Systems
  • Potassium and Related Disorders
  • Platelet Disorders and Treatments
  • Cardiac Structural Anomalies and Repair
  • Hemodynamic Monitoring and Therapy

Ospedale San Paolo
2021-2025

Royal Veterinary College
2016-2023

Stazione Sperimentale del Vetro
2020

University of Milan
2013-2016

Objectives To assess survival and risk factors in dogs with pulmonic stenosis. Methods A retrospective review of medical case records all cases stenosis >50 mmHg , undergoing pulmonary balloon valvuloplasty or not. Survival curves multivariate analysis were calculated the overall population subgroups. Results One hundred seventy‐two included. Factors negatively affecting clinical signs [hazard ratio ( HR ) 3 · 44, P < 0 001], younger age at diagnosis 96, = 001) valve morphology type B...

10.1111/jsap.12113 article EN Journal of Small Animal Practice 2013-07-24

Objective To report the occurrence of transient atrial fibrillation in dogs with degenerative mitral valve disease (DMVD) American College Veterinary Medicine (ACVIM) stage C/D, presenting acute clinical signs. Materials and Methods Retrospective multicentric case series DMVD ACVIM C/D (AF) hospitalised referral centres (2020 to 2024). Signalment, findings, treatments, electrocardiographic echocardiographic data outcomes were recorded. Results Eight included. All presented for deterioration...

10.1111/jsap.13855 article EN Journal of Small Animal Practice 2025-04-03

Background Veterinary literature lacks data about cardiovascular–renal disorders (Cv RD ) and cardiorenal‐anemia syndrome ( CRAS in dogs. Hypothesis A direct correlation exists between ACVIM class IRIS stage; chronic kidney disease CKD complicates mitral valve CMVD more often than does anemia Animals One hundred fifty‐eight client‐owned dogs with . Methods Signalment, physical examination findings, electrocardiography, thoracic radiographs, echocardiography, blood analysis were...

10.1111/jvim.14524 article EN cc-by-nc Journal of Veterinary Internal Medicine 2016-09-01

Thin and hypokinetic myocardial segments (THyMS) represent adverse ventricular (LV) remodeling in human hypertrophic cardiomyopathy. We describe the echocardiographic features outcome cats with THyMS, a subpopulation, phenotype before LV wall thinning was detected (pre-THyMS).Eighty client-owned cats.Retrospective multicenter study. Clinical records were searched for defined as segment(s) end-diastolic thickness (LVWT) <3 mm hypokinesis presence of ≥one LVWT >4 normal motion. When available,...

10.1016/j.jvc.2023.02.002 article EN cc-by Journal of Veterinary Cardiology 2023-02-10

Abstract Background Artificial intelligence (AI) could improve accuracy and reproducibility of echocardiographic measurements in dogs. Hypothesis A neural network can be trained to measure left ventricular (LV) linear dimensions Animals Training dataset: 1398 frames from 461 canine echocardiograms a single specialist center. Validation: 50 additional the same Methods right parasternal 4‐chamber long axis frame each study, labeled by 1 18 echocardiographers, marking anterior posterior points...

10.1111/jvim.17012 article EN cc-by Journal of Veterinary Internal Medicine 2024-02-16

Objectives Feline cardiomyopathies (CMs) represent a heterogeneous group of myocardial diseases. The most common CM is hypertrophic cardiomyopathy (HCM), followed by restrictive (RCM). Studies comparing survival and outcome for different types are scant. Furthermore, little known about the cardiovascular consequences systemic diseases on survival. aim this retrospective study was to compare prognostic factors in cats affected HCM, RCM or secondary referred our institution over 10 year...

10.1177/1098612x15588797 article EN Journal of Feline Medicine and Surgery 2015-06-09

Background Left ventricular ( LV ) systolic dysfunction is associated with increased risk of death in cats hypertrophic cardiomyopathy HCM ). Mitral and tricuspid annular plane excursion MAPSE TAPSE , respectively) are measures longitudinal function reduced human patients . Hypotheses Cats have lower compared to control cats; the presence congestive heart failure CHF survival time. Animals 64 27 healthy cats. Forty‐five were not showing clinical signs, 19 had Methods Retrospective study....

10.1111/jvim.14697 article EN cc-by-nc Journal of Veterinary Internal Medicine 2017-03-30

Abstract Background Cats with hypertrophic cardiomyopathy (HCM) have decreased left ventricular (LV) longitudinal deformation detected by mitral annular plane systolic excursion (MAPSE) and speckle tracking echocardiography. People preclinical HCM LV radial strain (S) rate (SR), preserved circumferential S SR. Hypothesis/Objectives compared to normal cats. Animals Seventy‐three client‐owned cats (n = 37) without 36) HCM. Methods Retrospective echocardiographic study. Left right SR, SR were...

10.1111/jvim.15495 article EN cc-by-nc Journal of Veterinary Internal Medicine 2019-04-16

Background Quantitative and semiquantitative methods have been proposed for the assessment of MR severity, though all are associated with limitations. Measurement vena contracta width ( VCW ) has used in clinical practice. Objective To measure dogs different levels severity. Animals Two hundred seventy‐nine were classified according to 5 Methods This was a retrospective study. EROA regurgitant volume calculated by PISA method, measured indexed BSA . Descriptive statistics index categories...

10.1111/jvim.12380 article EN other-oa Journal of Veterinary Internal Medicine 2014-06-16

Background Patent ductus arteriosus ( PDA ) is one of the most common congenital heart defects in dogs. Advanced echocardiographic techniques such as speckle‐tracking echocardiography STE have not been extensively used to evaluate cardiac function affected Hypothesis are more sensitive than standard analyzing systolic dogs with . Animals Forty‐four client‐owned dogs: 34 (preoperative evaluation) and 10 healthy sex‐ weight‐matched controls. Methods Prospective study. Dogs were recruited over...

10.1111/jvim.13938 article EN cc-by-nc Journal of Veterinary Internal Medicine 2016-05-01

Myxomatous mitral valve disease (MVD) is the most common acquired heart in dogs, and Cavalier King Charles Spaniel (CKCS) studied breed because of high prevalence, early onset hereditary component evidenced breed. MVD has different severity levels, there are many practical limitations identifying its asymptomatic stages. Proteomic techniques valuable for studying proteins peptides involved cardiovascular diseases, including period prior to clinical disease. The aim this study was identify...

10.1186/s12917-017-0951-5 article EN cc-by BMC Veterinary Research 2016-12-01

A 5-year-old, neutered male domestic shorthair cat was referred for evaluation of suspected hypothyroidism. In the previous 2 months, owner reported mild lethargy, weight gain with decreased appetite, unkempt hair coat, and an episode bilateral external otitis that temporarily improved after a 10-day treatment ear medications containing gentamicin, betamethasone, clotrimazole1; completed 50 days before presentation. The had been slightly overweight several months referring veterinarian...

10.1111/jvim.12283 article EN other-oa Journal of Veterinary Internal Medicine 2014-01-13

Patent ductus arteriosus (PDA) is 1 of the most common congenital heart defects in dogs and percutaneous closure effective achieving ductal closure; PDA associated with abrupt hemodynamic changes.A marked decrease standard parameters systolic function as assessed by M- or B-mode echocardiography after was identified previous studies. Speckle tracking can provide further insight into effect on cardiac mechanics affected PDA.Twenty-five client-owned PDA.Prospective study. Dogs were recruited...

10.1111/jvim.13919 article EN cc-by-nc Journal of Veterinary Internal Medicine 2016-05-01

Abstract Background Impairment of left ventricular (LV) longitudinal function is an early marker systolic dysfunction in hypertrophic cardiomyopathy (HCM). Aortic annular plane excursion (AAPSE) a measure LV people that has not been evaluated cats. Hypothesis lower cats with HCM compared to control cats, and stage C have the lowest AAPSE. Animals One hundred seventy‐five cats: 60 normal, 61 B 54 Materials Multicenter retrospective case‐control study. Electronic medical records from 4...

10.1111/jvim.16962 article EN cc-by Journal of Veterinary Internal Medicine 2023-12-01

Background: Quantitative assessment of mitral regurgitation (MR) severity has become increasingly important as surgical and catheter-based therapies for MR reduction available.Hypothesis/Objectives: Obtain quantitative measures across stages degenerative valve disease (DMVD) evaluate agreement between two methods.Animals: 51 client-owned dogs stratified three DMVD (ACVIM B1, B2, C).Methods: Regurgitant volume (RVol) fraction (RF) were measured on echocardiograms prospectively acquired by a...

10.1111/jvim.16913 article EN cc-by Journal of Veterinary Internal Medicine 2023-11-10

10.2460/javma.244.1.45 article EN Journal of the American Veterinary Medical Association 2013-12-17

10.2460/javma.243.6.787 article EN Journal of the American Veterinary Medical Association 2013-09-04

Pregnancy is associated with adaptation of the left ventricular (LV) function. Due to differences between breeds in baseline echocardiographic values and specific predispositions for myocardial diseases, breed-specific parameters may be helpful evaluate whether systolic function varies during pregnancy. This study enrolled nine healthy Great Dane bitches uncomplicated Echocardiographic M-mode B-mode data were collected before ovulation within 7 days predicted parturition term. Evaluated...

10.3390/ani10111992 article EN cc-by Animals 2020-10-29

This report describes the diagnostic findings, natural history and genetic analysis of candidate gene

10.1177/20551169241249003 article EN cc-by-nc Journal of Feline Medicine and Surgery Open Reports 2024-01-01

Abstract Bronchial and upper respiratory diseases have been associated with hypoxia subsequent development of pulmonary arterial hypertension (PAH). However, there are no known studies assessing the prevalence PAH in dogs these conditions. The aim this study was to assess frequency bronchial diseases. Medical records confirmed diagnosis (by endoscopic examination) and/or referred for cardiovascular investigation (January 2009 - May 2013) were retrospectively reviewed. Diagnosis made by...

10.1515/macvetrev-2016-0075 article EN cc-by Macedonian Veterinary Review 2016-02-10
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